Here’s What’s Next for Pig Organ Transplants
2022 was a breakthrough year for xenotransplantation, a procedure that could be a lifeline for patients in desperate need of a donor......»»
Organ transplant recipients remain vulnerable to COVID-19 even after second vaccine dose
In a new study, researchers show that although two doses of a vaccine against SARS-CoV-2 -- the virus that causes COVID 19 -- confers some protection for people who have received solid organ transplants, it's still not enough to enable them to dispen.....»»
Human organ chips enable COVID-19 drug repurposing
Emulating the human lung airway in vitro identified the SARS-CoV2-inhibiting effects of the antimalarial drug amodiaquine, which is now in COVID-19 clinical trials......»»
Scientists identify networks for spikelet formation in barley
Organ development in plants mostly occurs through combinatorial activity of so-called meristems. Meristems are plant cells or tissues that give rise to new organs, similar to stem cells in human—including spikelets. Spikelets are components of the.....»»
Genome editing in farm animals: Chickens and pigs with integrated genetic scissors
Researchers at the TUM have demonstrated a way to efficiently study molecular mechanisms of disease resistance or biomedical issues in farm animals. Researchers are now able to introduce specific gene mutations into a desired organ or even correct ex.....»»
Robust cell junctions are critical for maintaining stem cell function
The skin is the largest organ in the human body, and its outermost part, called the epidermis, is replenished every three weeks. The cells fueling this renewal of the epidermal stem cells are found in specialized areas or niches, within a region of t.....»»
A little squid and its glowing bacteria yield new clues to symbiotic relationships
The relationship between the Hawaiian bobtail squid and the bioluminescent bacteria living in its light organ has been studied for decades as a model of symbiosis. Now researchers have used a powerful chemical analysis tool to identify a small molecu.....»»
Sound-frequency map for inner ear created with advanced X-ray technology
Researchers have created the first 3D map of the hearing nerve showing where the various sound frequencies are captured. Using what is known as synchrotron X-ray imaging, they were able to trace the fine nerve threads and the vibrating auditory organ.....»»
Human lung and brain organoids respond differently to SARS-CoV-2 infection in lab tests
Researchers are using stem cell-derived organoids to study how SARS-CoV-2 interacts with various organ systems. Their findings may help explain the wide variety in COVID-19 symptoms and aid the search for therapies......»»
Bioengineered hybrid muscle fiber for regenerative medicine
Muscle constitutes the largest organ in humans, accounting for 40% of body mass, and it plays an essential role in maintaining life. Muscle tissue is notable for its unique ability for spontaneous regeneration. However, in serious injuries such as th.....»»
An inner sensor of body movement revealed in zebrafish
Researchers at Karolinska Institutet have revealed a central proprioceptive organ built directly into the central nervous system that acts as an inner movement sensor. The article was recently published in the journal Neuron......»»
The force to shape an organ
Carnegie Mellon University professor of biomedical engineering and materials science and engineering Adam Feinberg, along with postdoctoral fellow Dan Shiwarski and graduate student Joshua Tashman, have created a novel biosensor that reveals the mech.....»»
U.S. must unify atmospheric biology research or risk national security, scientists say
Global circulating winds can carry bacteria, fungal spores, viruses and pollen over long distances and across national borders, but the United States is ill-prepared to confront future disease outbreaks or food-supply threats caused by airborne organ.....»»
Lasers and molecular tethers create perfectly patterned platforms for tissue engineering
Imagine going to a surgeon to have a diseased or injured organ switched out for a fully functional, laboratory-grown replacement. This remains science fiction and not reality because researchers today struggle to organize cells into the complex 3-D a.....»»
How Will America"s Investigators Identify Capitol Hill Protesters?
"Both local police and the FBI are seeking information about individuals who were 'actively instigating violence' in Washington, DC, on January 6," writes Ars Technica. Then they speculate on which tools will be used to find them: While media organ.....»»
The First Pig-to-Human Organ Transplants Could Happen This Year
Every day in the United States, 17 people die waiting for a lifesaving organ transplant. To address this crisis, one biotech company is turning to an unlikely source: pigs. Maryland-based United Therapeutics says it plans to begin transplanting organ.....»»
FDA Approves Genetically Engineered Pigs
The Food and Drug Administration has approved genetically engineered pigs for use in food and medical products. The pigs, developed by medical company Revivicor, could be used in the production of drugs, to provide organs and tissues for transplants,.....»»
A genetic control of stem cell differentiation and organ maintenance by induction of fat metabolism
Fat metabolism (lipid metabolism) is the term used to describe the synthesis and degradation of lipids in cells. This is increasingly recognized as an important key process that could also influence the maintenance and differentiation of stem cells......»»