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Glycans can regulate their own biosynthesis by modifying enzyme activity

Glycans are chains of sugars that attach to cells through proteins or lipids, changing their chemical characteristics. Glycans can be incredibly complex and branched in structure, contributing to the stability of the extracellular domain of cells and.....»»

Category: topSource:  physorgOct 29th, 2024

Enzyme-powered "snot bots" help deliver drugs in sticky situations

Snot might not be the first place you'd expect nanobots to be swimming around. But this slimy secretion exists in more places than just your nose and piles of dirty tissues—it also lines and helps protect the lungs, stomach, intestines and eyes. An.....»»

Category: topSource:  physorgRelated NewsJul 17th, 2024

New analysis of Cassini data yields insights into Titan"s seas

A new study of radar experiment data from the Cassini-Huygens mission to Saturn has yielded fresh insights related to the makeup and activity of the liquid hydrocarbon seas near the north pole of Titan, the largest of Saturn's 146 known moons......»»

Category: topSource:  physorgRelated NewsJul 16th, 2024

Close your rings…but in watchOS 11, it’s okay if you don’t

Ever since the Apple Watch first debuted nearly a decade ago, its signature feature has been the three Activity rings: move, exercise, and stand. “Close your rings” has been the motivational mantra of the device. But what about when you’re i.....»»

Category: topSource:  informationweekRelated NewsJul 16th, 2024

Research team develops light-activated compounds to treat neuropathic pain

Light can be used to activate drugs in specific parts of the body through photopharmacology. This innovative approach involves modifying the chemical structure of a drug by adding a light-activated molecular switch, such as azobenzene. This allows th.....»»

Category: topSource:  physorgRelated NewsJul 12th, 2024

Social contagion research explores how ant colonies regulate group behaviors

In the world of social creatures, from humans to ants, the spread of behaviors through a group—known as social contagion—is a well-documented phenomenon. This process, driven by social imitation and pressure, causes individuals to adopt behaviors.....»»

Category: topSource:  physorgRelated NewsJul 12th, 2024

Research team models connection between enzyme activity and yields for the first time

A team from the University of Illinois has developed a modeling framework connecting enzyme activity related to photosynthesis to yield. This is the first time a model has tied the dynamic photosynthetic pathways directly to crop growth......»»

Category: topSource:  physorgRelated NewsJul 12th, 2024

New research reveals how galaxies avoid early death

Galaxies avoid an early death because they have a "heart and lungs" which effectively regulate their "breathing" and prevent them from growing out of control, a new study suggests......»»

Category: topSource:  physorgRelated NewsJul 12th, 2024

Biologists determine the liver is the source of free glycans in the bloodstream

In a rat study, RIKEN biologists have solved the mystery of where glycan molecules in the blood come from, tracking them down to the liver. This finding could lead to new biomarkers for liver-related diseases......»»

Category: topSource:  physorgRelated NewsJul 11th, 2024

Novel protein found to inhibit activity of CRISPR-Cas system

In a study published in Nature on July 3, researchers from the Institute of Biophysics of the Chinese Academy of Sciences and the University of Toronto, Canada, discovered a novel anti-CRISPR protein called AcrIF25, which inhibits the activity of the.....»»

Category: topSource:  physorgRelated NewsJul 11th, 2024

Team investigates chemical modifications to gain deeper insights into genetic regulation mechanisms

University of North Carolina at Chapel Hill researchers have determined whether a specific chemical modification of a protein that packages the genome called a histone affects gene activity and cell proliferation, according to the paper, "Drosophila.....»»

Category: topSource:  physorgRelated NewsJul 10th, 2024

Phage-derived enzyme targets E. faecalis biofilms to mitigate acute graft-versus-host disease

Allogenic hematopoietic cell transplantation (allo-HCT) involves transferring healthy donor stem cells to recipients with conditions such as blood cancer, bone marrow failure, or certain genetic blood disorders. Acute graft-versus-host disease (aGVHD.....»»

Category: topSource:  physorgRelated NewsJul 10th, 2024

Newly identified enzyme helps pathogenic fungus build protective cell wall

Researchers at the School of Medicine have identified a novel enzyme involved in building the cell wall of Cryptococcus neoformans, a fungus that causes lung infections and potentially deadly cases of meningitis, primarily in people with AIDS. About.....»»

Category: topSource:  informationweekRelated NewsJul 9th, 2024

Study finds ways to enhance transcription factor activity

Transcription factors regulate gene expression by binding specific sequences on DNA, which is an essential step to producing messenger RNAs from protein-coding genes. Denes Hnisz's lab, in collaboration with Martin Vingron's lab at the MPIMG, has dis.....»»

Category: topSource:  physorgRelated NewsJul 5th, 2024

How 36,000 buried tea bags help explain global decomposition

Co-developed by Umeå university, a method to measure the decay of plant material with the help of simple tea bags has quickly become the standard in scientific research as well as a favorite teaching activity throughout the world......»»

Category: topSource:  physorgRelated NewsJul 3rd, 2024

Discovering new anti-aging secrets from the world"s longest-living vertebrate

New experimental research shows that muscle metabolic activity may be an important factor in the incredible longevity of the world's oldest living vertebrate species—the Greenland shark. These findings may have applications for conservation of this.....»»

Category: topSource:  physorgRelated NewsJul 3rd, 2024

Researchers capture never-before-seen view of gene transcription

Every living cell transcribes DNA into RNA. This process begins when an enzyme called RNA polymerase (RNAP) clamps onto DNA. Within a few hundred milliseconds, the DNA double helix unwinds to form a node known as the transcription bubble, so that one.....»»

Category: topSource:  physorgRelated NewsJul 3rd, 2024

Q&A: How to make sustainable products faster with artificial intelligence and automation

By modifying the genomes of plants and microorganisms, synthetic biologists can design biological systems that meet a specification, such as producing valuable chemical compounds, making bacteria sensitive to light, or programming bacterial cells to.....»»

Category: topSource:  physorgRelated NewsMay 30th, 2024

Lava continues to flow from Iceland volcano but not at powerful level as eruption

Lava continued to spurt from a volcano in southwestern Iceland on Thursday but the activity had calmed significantly from when it erupted a day earlier......»»

Category: topSource:  physorgRelated NewsMay 30th, 2024

New modified CRISPR protein can fit inside virus used for gene therapy

Researchers have developed a novel version of a key CRISPR gene-editing protein that shows efficient editing activity and is small enough to be packaged within a non-pathogenic virus that can deliver it to target cells. Hongjian Wang and colleagues a.....»»

Category: topSource:  physorgRelated NewsMay 30th, 2024

The death of Vulcan: Study reveals planet is actually an astronomical illusion caused by stellar activity

A planet thought to orbit the star 40 Eridani A—host to Mr. Spock's fictional home planet, Vulcan, in the "Star Trek" universe—is really a kind of astronomical illusion caused by the pulses and jitters of the star itself, a new study shows......»»

Category: topSource:  physorgRelated NewsMay 28th, 2024