Glucagon receptor structures uncover new arrestin interaction mechanism
G protein-coupled receptors (GPCRs) are essential for cell signal transduction and constitute the largest drug target protein family. Upon agonist stimulation, these receptors activate multiple downstream transducers, including G proteins and arresti.....»»
Scientists make COVID receptor protein in mouse cells
A team of scientists at the U.S. Department of Energy's (DOE) Brookhaven National Laboratory and Columbia University has demonstrated a way to produce large quantities of the receptor that SARS-CoV-2, the virus that causes COVID-19, binds to on the s.....»»
Energy supply in human cells is subject to quality control, researchers discover
Researchers at the University Medical Center Göttingen (UMG) have discovered a new quality control mechanism that regulates energy production in human cells. This process takes place in mitochondria, the power plants of the cell......»»
New material opens up possibility of converting water pollutants into hydrogen gas
WPI Researchers have developed a material to remove urea from water and potentially convert it into hydrogen gas. By building these materials of nickel and cobalt atoms with carefully tailored electronic structures, the group has unlocked the potenti.....»»
Chilled-out tadpoles defy climate odds
University of Queensland researchers have discovered a previously unknown mechanism that allows tadpoles in cold environments to mitigate the detrimental effects of ultraviolet (UV) radiation......»»
New method for integrating electro-optic heterointerfaces in MIS structures for plasmonic waveguide modulation
Researchers at the University of Toronto, led by Dr. Amr S. Helmy, have developed a new method for integrating electro-optic SiO2/ITO heterointerfaces into metal–insulator–semiconductor (MIS) structures. This breakthrough is expected to lead to t.....»»
Research reveals gas-phase migration route for formation of strong metal-support interaction state
Strong metal-support interaction (SMSI) is one of the most important concepts in heterogeneous catalysis. Triggered by pretreatment or reaction processes, the supported metal nanoparticles may be partially or completely encapsulated by support-derive.....»»
New tomographic reconstruction algorithm sets world record
Advanced synchrotron tomography is a critical research tool, allowing scientists to explore the intricate structures of objects in extremely high resolution. Because this technique enables researchers to capture dynamics in real-time, it can capture.....»»
DNA construction leads to unexpected discovery of important cell function
Researchers at Karolinska Institutet in Sweden have used DNA origami, the art of folding DNA into desired structures, to show how an important cell receptor can be activated in a previously unknown way. The result opens new avenues for understanding.....»»
Citizen scientists needed to discover elusive black holes
Could you help scientists uncover the mysterious world of invisible black holes? Become a Black Hole Hunter and you'll be taking part in scientific research that has the potential to reveal more about one of space's most intriguing aspects......»»
Study delivers detailed photos of galaxies" inner structures
For the first time, high-resolution images captured by the James Webb Space Telescope are offering powerful insights into the complex dust patterns of nearby star-forming galaxies......»»
Discovery of low-lying isomeric states in cesium-136 has applications in particle astrophysics
Large, low-background detectors using xenon as a target medium are widely used in fundamental physics, particularly in experiments searching for dark matter or studying rare decays of atomic nuclei. In these detectors, the weak interaction of a neutr.....»»
Elucidating the biosynthetic mechanism for protoberberine alkaloids from Coptis chinensis
Protoberberine alkaloids are a group of tetracyclic isoquinoline compounds known for their well-established antimicrobial and anti-inflammatory properties. Although protoberberine alkaloids are broadly found in various plant families such as Ranuncul.....»»
Innovations in 2D root phenotyping uncover genetic keys to enhanced agricultural productivity
Root system architecture (RSA) plays a pivotal role in plant yield, shaped by evolution and ecological adaptations for effective nutrient and water uptake and abiotic stress resistance......»»
Concrete made stronger and more durable with resin
Engineering structures made of concrete, steel, or other materials are subject to vibrations and stress. Because of this, small cracks appear, which grow and eventually lead to destruction. This phenomenon is called "fatigue failure.".....»»
Climate change threatens fish supply: Tiny phytoplankton, big consequences
A research team that includes Dr. Angus Atkinson of the Plymouth Marine Laboratory and Dr. Axel Rossberg from Queen Mary University of London has discovered a hidden amplifying mechanism within the ocean's food web. Their findings, published in Natur.....»»
Light-matter interaction: Broken symmetry drives polaritons
An international team of scientists provide an overview of the latest research on light-matter interactions. A team of scientists from the Fritz Haber Institute, the City University of New York, and the Universidad de Oviedo has published a comprehen.....»»
New research deciphers biomineralization mechanism
Many organisms can produce minerals or mineralized tissue. A well-known example is nacre, which is used in jewelry because of its iridescent colors. Chemically speaking, its formation begins with a mollusk extracting calcium and carbonate ions from w.....»»
Critical GitLab flaw allows account takeover without user interaction, patch quickly! (CVE-2023-7028)
A critical vulnerability in GitLab CE/EE (CVE-2023-7028) can be easily exploited by attackers to reset GitLab user account passwords. While also vulnerable, users who have two-factor authentication enabled on their account are safe from account takeo.....»»
Scientists uncover ocean"s intricate web of microbial interactions across different depths
An international team of scientists led by researchers from the Institut de Ciències del Mar (ICM-CSIC) in Barcelona has uncovered the ocean's intricate web of microbial interactions across different depths. The research, which provides crucial insi.....»»
A three-step mechanism explaining ultraviolet-induced CO desorption from CO ice
The desorption of CO ice induced by ultraviolet (UV) radiation is a phenomenon that occurs in some cold parts of the universe, which has often also been replicated in laboratory settings. While this phenomenon is now well-documented, the molecular me.....»»