Glucagon receptor structures uncover new arrestin interaction mechanism
G protein-coupled receptors (GPCRs) are essential for cell signal transduction and constitute the largest drug target protein family. Upon agonist stimulation, these receptors activate multiple downstream transducers, including G proteins and arresti.....»»
Human odorant receptor for characteristic petrol note of Riesling wines identified
Climate change does not stop at grapevines. Too much sun means that the bouquet of German Riesling wines becomes dominated by a petrol note (some) customers do not appreciate. A research team from the Leibniz Institute for Food Systems Biology at the.....»»
Illuminating the path to hearing recovery: Structural insights into a receptor protein"s role in auditory function
Researchers have worked to uncover the mysteries surrounding a specific receptor protein associated with hearing. Professor Yunje Cho's research team from the Department of Life Sciences at Pohang University of Science and Technology (POSTECH, Republ.....»»
New time-resolved ultraviolet photodissociation mass spectrometry strategy for target protein stability analysis
How mutations impact protein stability and structure dynamics is crucial for understanding the molecular mechanism of the disease and the targeted drug design. However, probing the molecular details of mutation-induced subtle structure dynamics is st.....»»
IDnow VideoIdent Flex blends AI technology with human interaction
IDnow has unveiled VideoIdent Flex, a new version of its expert-led video verification service that blends advanced AI technology with human interaction. The human-based video call solution, supported by AI, has been designed and built to boost custo.....»»
Nanovials method for immune cell screening uncovers receptors that target prostate cancer
A recent UCLA study demonstrates a new process for screening T cells, part of the body's natural defenses, for characteristics vital to the success of cell-based treatments. The method filters T cells based on the receptor proteins found on their sur.....»»
Chemists devise easier new method for making a common type of building block for drugs
Ring-shaped chemical structures called saturated heterocycles are found in most FDA-approved drugs but are often difficult to create. Scripps Research chemists have just developed a surprisingly easy method for making many of these sought-after compo.....»»
Researchers discover the secret of how termites build their giant nests
Termites are the architects of the natural world. The nests that they build can reach meters of height, with complex and elaborate structures, galleries that ensure efficient communication and that automatically ventilate the nest interior in a way t.....»»
Laser-patterned thin films that swell into kirigami-like structures offer new opportunities in hydrogel technology
New options for making finely structured soft, flexible and expandable materials called hydrogels have been developed by researchers at Tokyo University of Agriculture and Technology (TUAT)......»»
Ocean currents threaten to collapse Antarctic ice shelves, study finds
A new study published in Nature Communications has revealed that the interplay between meandering ocean currents and the ocean floor induces upwelling velocity, transporting warm water to shallower depths. This mechanism contributes substantially to.....»»
Scientists reconstruct assembly of the human centriole, image by image, for the first time
Cells contain various specialized structures—such as the nucleus, mitochondria or peroxisomes—known as "organelles." Tracing their genesis and determining their structure is fundamental to understanding cell function and the pathologies linked to.....»»
Researchers develop mechanism of electrical 180° switching of Néel vector in spin-splitting antiferromagnet
A research team led by The Hong Kong University of Science and Technology (HKUST) and Tsinghua University has theoretically proposed a new mechanism of electrical 180° switching of Néel vector and experimentally realized it in antiferromagnetic mat.....»»
Scientists discover new phage resistance mechanism in phage-bacterial arms race
One of the most abundant and deadliest organisms on Earth is a virus called a bacteriophage (phage). These predators have lethal precision against their targets—not humans, but bacteria. Different phages have evolved to target different bacteria an.....»»
FASER measures high-energy neutrino interaction strength
Operating at CERN's Large Hadron Collider (LHC) since 2022, the FASER experiment is designed to search for extremely weakly interacting particles. Such particles are predicted by many theories beyond the Standard Model that are attempting to solve ou.....»»
Team develops portable swept-source Raman spectrometer for chemical and biomedical applications
In 1928, Indian physicist Sir C. V. Raman and his colleague K. S. Krishnan discovered that when light interacts with matter, parts of the scattered light undergo changes in energy due to interaction with molecular vibrations, resulting in what is kno.....»»
Chinese scientists reveal the spinning mechanism of the silkworm
Mulberry silk is a natural protein fiber that is light, soft and fine in nature, known as the "second skin of the human body" and "Queen of fibers." China is the origin of the world's sericulture industry......»»
Cybersecurity jobs available right now: April 3, 2024
Cyber Security Manager Charterhouse Middle East | UAE | On-site – View job details The Cyber Security Manager will identify and address potential security issues, define access privileges, implement control structures, and conduct per.....»»
Catkins are flowering at different times, threatening their pollination and the wildlife that feed on them
As the days grow longer and the air warms up, nature is bursting back to life. Even before their leaves return, trees produce delicate, fuzzy structures known as catkins. These tiny, downy threads, often described as kitten tails (thanks to a fun tra.....»»
Researchers discover corn reduces arsenic toxicity in soil
When crops grow in arsenic-contaminated soil, this toxic element accumulates in the food chain. A study involving the University of Basel has now discovered a mechanism used by corn plants to reduce arsenic uptake: the key factor is a special substan.....»»
Team demonstrates an ultra-broadband tunable terahertz absorber of graphene and hierarchical plasmonic metamaterials
Perfect absorption arises from the strong interaction of valence electrons with light in a conducting material. Optical metamaterial is an effective approach to exploit the superior photon capture capability. Thus, the perfect absorbers could be achi.....»»
Closer to Earth: A new technique for examining ultralow velocity zones at Earth"s core-mantle boundary
The core-mantle boundary (CMB) is crucial for the Earth's magnetic field and rotation. It is known that this boundary harbors complex structures, including ultralow velocity zones (ULVZs), characterized by significantly slowed seismic wave velocities.....»»