Freeze! Executioner protein caught in the act
A new molecular 'freeze frame' technique has allowed WEHI researchers to see key steps in how the protein MLKL kills cells......»»
A powerful technique for tracking a protein"s fleeting shape changes
Researchers at Weill Cornell Medicine have developed a powerful, new technique to generate "movies" of changing protein structures and speeds of up to 50 frames per second......»»
New class of antimicrobials discovered in soil bacteria
Researchers have discovered toxic protein particles, shaped like umbrellas, that soil bacteria known as Streptomyces secrete to squelch competitors, especially others of their own species......»»
Illuminating the path to hearing recovery: Structural insights into a receptor protein"s role in auditory function
Researchers have worked to uncover the mysteries surrounding a specific receptor protein associated with hearing. Professor Yunje Cho's research team from the Department of Life Sciences at Pohang University of Science and Technology (POSTECH, Republ.....»»
New time-resolved ultraviolet photodissociation mass spectrometry strategy for target protein stability analysis
How mutations impact protein stability and structure dynamics is crucial for understanding the molecular mechanism of the disease and the targeted drug design. However, probing the molecular details of mutation-induced subtle structure dynamics is st.....»»
See what the solar eclipse looked like from space
The astronauts on board the International Space Station caught a stunning glimpse of this week's solar eclipse, and NASA has shared some images......»»
New study details how starving cells hijack protein transport stations
A new study details how nutrient-starved cells divert protein transport stations to cellular recycling centers to be broken down, highlighting a novel approach cells use to deal with stressful conditions......»»
Researchers develop method to extract useful proteins from beer-brewing leftovers
Researchers from Nanyang Technological University, Singapore (NTU Singapore), have created a method that extracts more than 80% of the available protein in grain leftovers from brewing beer, commonly known as brewers' spent grain......»»
A promising target for new RNA therapeutics now accessible
Only recently, a new era in medicine began with the first RNA vaccines. These active substances are modified RNAs that trigger immune responses of the human immune system. Another approach in RNA medicine targets the body's own RNA and its protein mo.....»»
New protein imaging method supports the design of innovative new cancer drugs
Scientists have successfully used a new imaging technique to determine the structure and interactions of a protein complex that plays a significant part in the initiation and progression of cancer. They showed that it was possible to use a high-resol.....»»
Scientists report that buffer and pH strongly affect the phase separation of SARS-CoV-2 N protein
In a new paper published in Molecular Biology of the Cell, the Allain lab (IBC) reported that the phase separation of the SARS-CoV-2 N protein strongly depends on the chosen buffer and pH. For example, the protonation of a single histidine side chain.....»»
Ford cuts EV plans even as it becomes nation’s second-largest EV brand
Ford is selling more EVs than ever, but it wants to build more hybrids instead. Enlarge / Electric F-150 sales are up 80 percent year over year. (credit: Ford) Ford has caught a case of electric vehicle pessimism and is.....»»
New method reveals secrets of protein interactions with potential for drug discovery
Scientists from the University of Oulu (Finland) and Texas A&M University (U.S.), have developed a new method to study how proteins interact with small ligand molecules, paving the way, for example, for faster and more efficient drug discovery......»»
New study paves the way for precision drugs to treat blood cancers
The Janus kinase 2 (JAK2) protein mediates signaling from several cytokine receptors in the regulation of hematopoiesis and immune responses. Somatic mutations in human JAK2 lead to constitutive activation and cytokine-independent signaling and under.....»»
Chinese scientists reveal the spinning mechanism of the silkworm
Mulberry silk is a natural protein fiber that is light, soft and fine in nature, known as the "second skin of the human body" and "Queen of fibers." China is the origin of the world's sericulture industry......»»
Salmon populations are struggling, bringing economic woes for California"s fishing fleet
On the docks at Pillar Point Harbor, fishing crews have been arriving with loads of freshly caught Dungeness crab......»»
Texas man busted with over two dozen counterfeit Apple devices
A Texas man has been charged with trademark counterfeiting after he was caught with more than $20,000 worth of counterfeit Apple products.Image Credit: KPRC Click2HoustonOn March 29, Conelle Davis was stopped by the Houston police while driving a sto.....»»
Hundreds of animals were rescued after the Black Summer bushfires, but how many actually survived?
The horrific Black Summer bushfires of 2019–20 burned more than 8 million hectares of vegetation across southeastern Australia. An estimated 3 billion animals were caught in the fire zone......»»
Chemists discover a key protein in how lysosomes work
Lysosomes, often reductively referred to as the "garbage disposals" of cells, play a pivotal role in our cells' digestive systems by getting rid of unwanted materials......»»
Study identifies protein responsible for gas vesicle clustering in bacteria
Gas vesicles are hollow structures made of protein found in the cells of certain microorganisms, and researchers at Rice University believe they can be programmed for use in biomedical applications......»»
Researcher creates algorithm to aid in discovery of new medicines
Ph.D. candidate Jeroen Methorst has developed a computer system that helps researchers find the protein they need to create new medicines. "Our whole group is now using this program," says Methorst. He will defend his Ph.D. thesis on April 2......»»