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Flexibility may be the key to potent peptides for treating diabetes

A little wiggle room might be just what the doctor ordered......»»

Category: topSource:  physorgDec 22nd, 2021

Discovery of new plant protein fold may be seed for anti-cancer drugs

University of Michigan researchers are celebrating their discovery of a new plant biochemistry and its unusual ability to form cyclic peptides—molecules that hold promise in pharmaceuticals as they can bind to challenging drug targets......»»

Category: topSource:  physorgRelated NewsFeb 14th, 2024

Asbury gives itself flexibility with relaxed 2025 revenue goal

Asbury CEO David Hult told the more flexible goals are meant to avoid the company focusing on too specific a target to the point of detrimental business decision-making......»»

Category: topSource:  autonewsRelated NewsFeb 9th, 2024

Comparing Different Hosting Platforms: WordPress vs. Wix vs. Squarespace

In the dynamic world of web hosting, finding the appropriate platform is a pivotal resolution that drastically influences your website’s performance, design flexibility, and ease of use. Among the myriad internet hosting alternatives available,.....»»

Category: topSource:  tapscapeRelated NewsFeb 7th, 2024

Unlocking artemisinin production secrets in Artemisia annua: The role of DBR2-like gene variations

Artemisia annua is the only known plant source of potent antimalarial artemisinins, and its chemotypes are classified as low- and high-artemisinin producing (LAP and HAP). However, the different mechanisms of artemisinin production by these two chemo.....»»

Category: topSource:  physorgRelated NewsFeb 6th, 2024

Uganda pesticide risk rises after AGOA expulsion

Ugandans are at increased risk of diabetes and cancer in the wake of the country's expulsion from a trade pact with the U.S., nutritionists say......»»

Category: topSource:  theglobeandmailRelated NewsFeb 1st, 2024

GM"s revived PHEV plans offer flexibility in North America

CEO Mary Barra did not say which segments GM will target with plug-in hybrids or when they would arrive, though they are not expected this year......»»

Category: topSource:  autonewsRelated NewsFeb 1st, 2024

Endangered seabird shows surprising individual flexibility to adapt to climate change

How individual animals respond to climate change is key to whether populations will persist or go extinct. Many species are shifting their ranges as the environment warms, but up to now the mechanisms underlying this have been unclear. For Europe's m.....»»

Category: topSource:  theglobeandmailRelated NewsJan 29th, 2024

Study tracks how wetland tree stem emissions vary by season, location, and hydrological conditions

The recent rise in atmospheric methane (CH4) has drawn increased attention to the potent greenhouse gas, which is approximately 45 times more powerful than carbon dioxide at trapping heat in the atmosphere. About 60% of global methane emissions are a.....»»

Category: topSource:  physorgRelated NewsJan 26th, 2024

Snake venom research has broad implications for bite treatment

Studying how rattlesnakes regulate their venom gives us important insight into how their genes are controlled. It also highlights the challenges in treating snakebites, according to new research in the journal Genome Biology and Evolution......»»

Category: topSource:  informationweekRelated NewsJan 26th, 2024

Researchers uncover molecular mechanisms behind effects of MXene nanoparticles on muscle regeneration

Tissue engineering, which involves the use of grafts or scaffolds to aid cell regeneration, is emerging as a key medical practice for treating volumetric muscle loss (VML), a condition where a significant amount of muscle tissue is lost beyond the bo.....»»

Category: topSource:  physorgRelated NewsJan 24th, 2024

Researchers develop nanofiber-based drug delivery system for skin cancer

Treating complex diseases such as skin cancer often requires simultaneous administration of multiple anticancer drugs. The delivery of such life-saving therapeutic drugs has evolved with the rise of nanotechnology-based drug carriers. Nanoplatforms o.....»»

Category: topSource:  physorgRelated NewsJan 24th, 2024

Fingerprinting biomolecules with the help of sound

A team of researchers from the Institute for Optoelectronic Systems and Microtechnology at Universidad Politécnica de Madrid (UPM) has designed a biosensor capable of identifying proteins and peptides in quantities as low as a single monolayer. For.....»»

Category: topSource:  physorgRelated NewsJan 22nd, 2024

Pay, flexibility, career growth keys to auto retail retention

Changes to pay and work schedules are two ways to retain auto retail employees who are considering leaving the job, according to the Automotive News Dealership Salary Survey and Hireology CEO Adam Robinson......»»

Category: topSource:  autonewsRelated NewsJan 22nd, 2024

Researchers observe how the flexibility of a protein hinge is crucial to the transfer of cell proteins

Ubiquitination—the addition of the protein ubiquitin—is a key stage in many cell processes, such as protein degradation, DNA repairs, and signal transduction. Using high-speed atomic force microscopy (HS-AFM) and molecular modeling, researchers l.....»»

Category: topSource:  physorgRelated NewsJan 18th, 2024

Researchers address formulation, manufacturing challenges in obesity, diabetes drugs

Medications such as Ozempic and Mounjaro are composed of molecules called acylated peptides that are designed to circulate in the body and regulate insulin production. This enables adults with type 2 diabetes to take a weekly injection instead of mon.....»»

Category: topSource:  physorgRelated NewsJan 17th, 2024

Meet pAblo·pCasso: A new leap in CRISPR technologies for next-gen genome engineering

A new CRISPR-Cas toolkit, dubbed "pAblo·pCasso," is set to transform the landscape of bacterial genome editing, offering unprecedented precision and flexibility in genetic engineering. The new technology, developed by researchers at The Novo Nordisk.....»»

Category: topSource:  physorgRelated NewsJan 16th, 2024

Scientists open door to achieving high-precision "slippery structural hydrogel"

Hydrogels inevitably undergo dehydration, structural collapse, and shrinkage deformation due to the uninterrupted evaporation in the atmosphere, thereby losing their flexibility, slipperyness, and manufacturing precision......»»

Category: topSource:  physorgRelated NewsJan 16th, 2024

How fruit bats evolved to consume so much sugar may have implications for diabetes research

A high-sugar diet is bad news for humans, leading to diabetes, obesity and even cancer. Yet fruit bats survive and even thrive by eating up to twice their body weight in sugary fruit every day......»»

Category: topSource:  informationweekRelated NewsJan 9th, 2024

Q&A: Researchers highlight the potential for microrobots in diagnosing and treating infectious diseases

Biofilms—structured communities of microorganisms that create a protective matrix shielding them from external threats, including antibiotics—are responsible for about 80% of human infections and present a significant challenge in medical treatme.....»»

Category: topSource:  physorgRelated NewsJan 8th, 2024

Exploring dimensions of justice in climate science

How can climate policy be made more just and fair? IIASA researchers have synthesized different dimensions of justice into a framework that can be used by climate scientists and policymakers, explaining how previous research has neglected many potent.....»»

Category: topSource:  physorgRelated NewsJan 8th, 2024