Drug is promising against pancreatic and breast cancers
The drug is effective at treating pancreatic cancer and prolonging survival in mice, according to a new study. A second study shows the drug is also effective against triple-negative breast cancer, a fast-growing and hard-to-treat type of breast canc.....»»
Multi-drug resistant bacteria found on International Space Station mutate to become functionally distinct
Principal Investigator Dr. Kasthuri Venkateswaran of NASA's Jet Propulsion Laboratory led a team that studied 13 strains of the bacterial species Enterobacter bugandensis that were isolated from the International Space Station (ISS). E. bugandensis i.....»»
New time-resolved ultraviolet photodissociation mass spectrometry strategy for target protein stability analysis
How mutations impact protein stability and structure dynamics is crucial for understanding the molecular mechanism of the disease and the targeted drug design. However, probing the molecular details of mutation-induced subtle structure dynamics is st.....»»
US citizen who was arrested in Moscow on drug charges appears in court
US citizen who was arrested in Moscow on drug charges appears in court.....»»
Scientists develop maleic acid-treated bacterial cellulose gel for enhancing bone repair
The field of bone tissue engineering (BTE) is a promising avenue for addressing bone injuries and defects by constructing artificial scaffolds with bionic functionalities. Due to its unique 3D network structure, impressive mechanical properties, and.....»»
US drug shortages reach record high with 323 meds now in short supply
The shortages affect everything from generic cancer drugs to ADHD medication. Enlarge / Takeda Pharmaceutical Co. Adderall XR brand medication arranged at a pharmacy in Provo, Utah, in November 2023. (credit: Getty | George Frey).....»»
Scientists find new ways to convert inhibitors into degraders, paving the way for future drug discoveries
Researchers have discovered ways to convert inhibitor-style targeted cancer drugs into small molecules known as degraders, which help destroy cancer-promoting proteins in cells......»»
A new coating method in mRNA engineering points the way to advanced therapies
Medicine can help to treat certain illnesses; for example, antibiotics can help overcome infections, but a new, promising field of medicine involves providing our body with the "blueprint" for how to defeat illnesses on its own......»»
US announces tough tap water standards for "forever chemicals"
US President Joe Biden's administration on Wednesday announced the first nationwide tap water standards to protect the public from toxic "forever chemicals" linked to serious health harms ranging from cancers to developmental damage in children......»»
Global collaboration discovers drug target to combat chronic lung infection
Scientists have discovered a target for the development of a drug to combat a bacterium that can cause chronic lung infection in hospitalized patients, immunocompromised individuals and people with cystic fibrosis......»»
A promising target for new RNA therapeutics now accessible
Only recently, a new era in medicine began with the first RNA vaccines. These active substances are modified RNAs that trigger immune responses of the human immune system. Another approach in RNA medicine targets the body's own RNA and its protein mo.....»»
New molecular device unlocks potential for targeted drug delivery and self-healing materials
In a new breakthrough that could revolutionize medical and material engineering, scientists have developed a first-of-its-kind molecular device that controls the release of multiple small molecules using force......»»
Drug delivery innovation: Multifunctional system based on switchable peptide-stabilized emulsions
A new study led by Prof. Meital Reches of the Hebrew University with Mr. Daniel Boas, a Ph.D. student in her group and team of collaborators, has pioneered a new drug delivery system centered on switchable peptide-stabilized emulsions......»»
New statistical-modeling workflow may help advance drug discovery and synthetic chemistry
A new automated workflow developed by scientists at Lawrence Berkeley National Laboratory (Berkeley Lab) has the potential to allow researchers to analyze the products of their reaction experiments in real time, a key capability needed for future aut.....»»
Novel tech captures disease markers in a snap: The future of early diagnosis
Extracellular vesicles (EVs) have emerged as promising biomarkers for non-invasive disease diagnostics, offering an alternative to conventional biopsies. However, the challenge has been the efficient and pure isolation of EVs from biological fluids,.....»»
Advancing real-time 3D holographic display: A new method for computer-generated holography
Holographic displays offer a promising avenue for achieving lifelike 3D reproductions with continuous depth sensation, holding potential applications in fields such as entertainment, medical imaging, and virtual reality. However, the conventional met.....»»
$158,000 ALS drug pulled from market after failing in large clinical trial
The drug is now unavailable to new patients; its maker to lay off 70% of employees. Enlarge (credit: Amlyx) Amylyx, the maker of a new drug to treat ALS, is pulling that drug from the market and laying off 70 percent of.....»»
He Got a Pig Kidney Transplant. Now Doctors Need to Keep It Working
Researchers think a combination of genetic edits and an experimental immunosuppressive drug could make the first pig kidney transplant a long-term success......»»
New method reveals secrets of protein interactions with potential for drug discovery
Scientists from the University of Oulu (Finland) and Texas A&M University (U.S.), have developed a new method to study how proteins interact with small ligand molecules, paving the way, for example, for faster and more efficient drug discovery......»»
New study paves the way for precision drugs to treat blood cancers
The Janus kinase 2 (JAK2) protein mediates signaling from several cytokine receptors in the regulation of hematopoiesis and immune responses. Somatic mutations in human JAK2 lead to constitutive activation and cytokine-independent signaling and under.....»»
You should keep your eye on these promising Xbox indies
Xbox showed us 8 upcoming indie games under its ID@Xbox banner, and each one is worth keeping an eye on......»»