Droplets in cells found to determine the accumulation of proteins in age-related diseases
Tiny droplets in cells can accelerate the accumulation of protein deposits in diseases such as Alzheimer's and Parkinson's disease, but they can also hinder this accumulation. While they will worsen the accumulation if the proteins stick to the edge.....»»
Imaging-based biomarker set to quantify aging at a cellular level
An international team of scientists has developed a method to measure biological aging with unparalleled precision that has the potential to change the way we approach aging and age-related diseases......»»
Experimental nanomedicine delivers chemo drugs directly to tumors in mice
Researchers at the University of Chicago Medicine Comprehensive Cancer Center have developed a nanomedicine that increases the penetration and accumulation of chemotherapy drugs in tumor tissues and effectively kills cancer cells in mice......»»
Social media interviews uncover New Yorkers" frustrations with high energy costs and reliability
Researchers at Columbia University Mailman School of Public Health are using a novel interview method to assess New Yorkers' perceptions and feelings related to their difficulties paying for and controlling heating and cooling in their homes. Inspire.....»»
With AI, extreme microbe reveals how life"s building blocks adapt to high pressure
An assist from a Google Artificial Intelligence tool has helped scientists discover how the proteins of a heat-loving microbe respond to the crushing conditions of the planet's deepest ocean trenches, offering new insights into how these building blo.....»»
Pausing biological clock could give boost to lab-produced blood stem cells
A decade ago, Raquel Espin Palazon discovered that inflammatory signaling pathways must switch on for embryos to produce blood stem cells. The latest work from her lab shows the potential value of keeping those same signals switched off after their i.....»»
Silver nanoparticles and a new sensing method can fight back against antibiotic-resistant biofilms
From safeguarding our food supply to preventing hospital infections, the battle against antibiotic-resistant bacteria is a growing challenge. Some bacteria can form biofilms, thick aggregates of millions of individual cells surrounded by protective m.....»»
How to merge and unmerge cells in Microsoft Excel
Microsoft Excel has numerous powerful data analysis functions, but sometimes you need to do something simple like merge some cells. Here's how......»»
Biomolecules inside living cells can now be seen with infrared light thanks to new method
To accelerate biotechnology innovations, such as the development of lifesaving drug therapies, scientists strive to develop faster, more quantitative and more widely available ways to observe biomolecules in living cells......»»
Scientists learn how to drug wily class of disease-causing enzymes
UCSF scientists have discovered how to target a class of molecular switches called GTPases that are involved in a myriad of diseases from Parkinson's to cancer and have long been thought to be "undruggable.".....»»
Uncovering the unique roles of Exportin-5 in RNA export within Drosophila cells
Eukaryotic cells are complex biological units, each with multiple membrane-bound compartments. These cells use specialized mechanisms to export biomolecules from their synthesis site to where they function......»»
Glitch in protein synthesis could affect tumor growth
During protein synthesis, or translation, genetic information transcribed in the cell's mRNA directs the stringing together of amino acids—the building blocks of proteins. As the translation machinery carouses along the string of nucleotides that m.....»»
How context-specific factors control gene activity
Every cell in our body contains the same DNA, yet liver cells are different from brain cells, and skin cells differ from muscle cells. What determines these differences? It all comes down to gene regulation; essentially how and when genes are turned.....»»
Leaving behind its crew, Starliner departs space station and returns to Earth
"We will review the data and determine the next steps for the program," says Boeing's Starliner manager. Enlarge / Boeing's Starliner spacecraft after landing Friday night at White Sands Space Harbor, New Mexico. (credit: Boeing.....»»
Scientists Destroy 99% of Cancer Cells in Lab With Vibrating Molecules
Scientists Destroy 99% of Cancer Cells in Lab With Vibrating Molecules.....»»
Harnessing the power of AI for climate change impact assessment
As climate change continues to intensify, the world is seeing an increase in the number and intensity of climate- and weather-related disasters. The UN member states need to develop urgent mitigation and adaptation actions based on reliable climate c.....»»
Solving the side effect problem of siRNA drugs for genetic disease treatment
Small interfering RNA (siRNA) drugs are a class of therapeutic agents that silence specific genes associated with inherited diseases. However, siRNA drugs have challenges because siRNAs often silence genes other than the target ones, causing side eff.....»»
Hijacking the command center of the cell: Nuclear parasites in deep-sea mussels
Most animals live in intimate relationships with bacteria. Some of these bacteria live inside the cells of their hosts, but only very few are able to live inside cell organelles (structures inside the cell, like organs in the body). One group of bact.....»»
Global experts present early-stage recommendations for nanomedicine development
They're tiny drug-delivery systems 1,000 times smaller than a human hair, but while nanomedicines have long been hailed as the future for treating debilitating and life-threatening diseases, their journey from lab to patient has many challenges......»»
NASA sets Europa Clipper launch date, despite Jupiter’s radiation concerns
Following a series of tests to determine the Europa Clipper’s ability to withstand radiation, NASA has finally approved a launch date: October 10. Though an … The post NASA sets Europa Clipper launch date, despite Jupiter’s radiation co.....»»
Decoding the language of cells with the power of proteomics
Hundreds of millions of years ago, single cells joined forces to become multicellular organisms. At the foundation of this multicellular world is the cell surface: the plasma membrane surrounding each cell, where individual units meet and communicate.....»»