CRISPR now possible in cockroaches
Researchers have developed a CRISPR-Cas9 approach to enable gene editing in cockroaches, according to a study published by Cell Press on May 16th in the journal Cell Reports Methods. The simple and efficient technique, named "direct parental" CRISPR.....»»
Scientists boost gene knockdown in human cells with CRISPR-Cas13 using chemically modified guide RNAs
In the latest of ongoing efforts to expand technologies for modifying genes and their expression, researchers in the lab of Neville Sanjana at New York University (NYU) and the New York Genome Center (NYGC) have developed chemically modified guide RN.....»»
Scientists harness the naturally abundant CRISPR-Cas system to edit superbugs
A research team led by Dr. Aixin Yan, Associate Professor from the Research Division for Molecular & Cell Biology, Faculty of Science, in collaboration with Honorary Clinical Professor Patrick Cy Woo from the Department of Microbiology, Li Ka Shing F.....»»
Gene editing "blocks virus transmission" in human cells
Scientists have used CRISPR gene-editing technology to successfully block the transmission of the SARS-CoV-2 virus in infected human cells, according to research released Tuesday that could pave the way for COVID-19 treatments......»»
Sweet success: First precision breeding of sugarcane with CRISPR-Cas9
Sugarcane is one of the most productive plants on Earth, providing 80 percent of the sugar and 30 percent of the bioethanol produced worldwide. Its size and efficient use of water and light give it tremendous potential for the production of renewable.....»»
NASA Astronauts Used CRISPR Gene Editing Technology For the First Time in Space
India's CNN-News18 reports: [P]revious research has found that how cells pick a particular repair strategy can be influenced by the microgravity conditions in space. Scientists are concerned that DNA repairs influenced by microgravity conditions may.....»»
Three-in-one approach boosts the silencing power of CRISPR
Originally discovered as a bacterial mode of defense against invading viruses, the remarkable ability of CRISPR-Cas9 to modify specific locations of DNA has made it a researcher favorite among gene editing tools. The ongoing effort to explore further.....»»
Astronauts demonstrate CRISPR/Cas9 genome editing in space
Researchers have developed and successfully demonstrated a novel method for studying how cells repair damaged DNA in space. Sarah Stahl-Rommel of Genes in Space and colleagues present the new technique in the open-access journal PLOS ONE on June 30,.....»»
Researcher introduces new CRISPR 3.0 system for highly efficient gene activation in plants
In a study in Nature Plants, Yiping Qi, associate professor of Plant Science at the University of Maryland (UMD), introduces a new and improved CRISPR 3.0 system in plants, focusing on gene activation instead of traditional gene editing. This third g.....»»
An algorithm to make CRISPR gene editing more precise
Researchers from Aarhus University and University of Copenhagen have developed a new method, which makes CRISPR gene editing more precise than conventional methods. The method selects the molecules best suited for helping the CRISPR-Cas9 protein with.....»»
Researchers improve efficiency and accessibility of CRISPR
One of the most powerful tools available to biologists these days is CRISPR-Cas9, a combination of specialized RNA and protein that acts like a molecular scalpel, allowing researchers to precisely slice and dice pieces of an organism's genetic code......»»
Synthetic SPECIES developed for use as a confinable gene drive
CRISPR-based technologies offer enormous potential to benefit human health and safety, from disease eradication to fortified food supplies. As one example, CRISPR-based gene drives, which are engineered to spread specific traits through targeted popu.....»»
CRISPR-Cas components work together to enhance protection from viruses
Researchers from Skoltech and their colleagues from Russia and the U.S. have shown that the two components of the bacterial CRISPR-Cas immunity system, one that destroys foreign genetic elements such as viruses and another that creates "memories" of.....»»
Sterilizing skeeters using CRISPR/Cas9
Mosquitoes are one of humanity's greatest nemeses, estimated to spread infections to nearly 700 million people per year and cause more than one million deaths......»»
Using CRISPR to lower cholesterol levels in monkeys
A team of researchers from Verve Therapeutics and the Perelman School of Medicine at the University of Pennsylvania has developed a CRISPR gene-editing technique that lowered the levels of cholesterol in the blood of test monkeys. In their paper publ.....»»
New genetic copycatchers detect efficient and precise CRISPR editing in a living organism
Scientists have developed a novel genetic sensor called a 'CopyCatcher,' which capitalizes on CRISPR-based gene drive technology, to detect instances in which a genetic element is copied precisely from one chromosome to another throughout cells in th.....»»
New genetic "CopyCatchers" detect efficient and precise CRISPR editing in a living organism
Researchers at the University of California San Diego have laid the groundwork for a potential new type of gene therapy using novel CRISPR-based techniques......»»
CRISPR tech could enable early diagnosis of devastating citrus disease
Penn State and U.S. Department of Agriculture scientists have used cutting-edge CRISPR/Cas technology to develop a diagnostic test that could enable early diagnosis of citrus greening, or Huanglongbing, a serious disease that threatens worldwide citr.....»»
New, rapid CRISPR/Cas9 method identifies key genes in zebrafish spinal cord regeneration
A new, rapid screening approach uses CRISPR/Cas9 technology to identify immune system-related genes that play a crucial role in repairing zebrafish spinal cord injuries......»»
Single-cell CRISPR technology deciphers role of chromatin accessibility in cancer
Researchers have developed CRISPR-sciATAC, a novel integrative genetic screening platform that jointly captures CRISPR gene perturbations and single-cell chromatin accessibility genome-wide. The new method harnesses the programmability of the gene ed.....»»
Move over CRISPR, the Retrons are coming
Researchers have created a new gene editing tool called Retron Library Recombineering (RLR) that can generate up to millions of mutations simultaneously, and 'barcodes' mutant bacterial cells so that the entire pool can be screened at once. It can be.....»»