Converting P450 peroxygenase into peroxidase via mechanism-guided protein engineering
Enzyme catalysis is a promising green solution for producing pharmaceuticals, fine chemicals, and biofuels. However, exploring their catalytic promiscuity to expand and enhance the capabilities of enzymes remains challenging......»»
Mathematical method for spectral density estimation set to unlock ocean mysteries
Researchers at The University of Western Australia's ARC Industrial Transformation Research Hub for Transforming Energy Infrastructure through Digital Engineering (TIDE) have made a significant mathematical breakthrough that could help transform ocea.....»»
Pear-derived discovery: A genetic mechanism to fortify crops against drought
A recent study has shed light on a critical genetic mechanism that boosts plants' ability to withstand drought. The research uncovers the role of the transcription factor PbERF3, native to wild pears, which works in concert with the protein PbHsfC1a.....»»
Scientists uncover conserved mechanism of pericentric heterochromatin initiation in vertebrates
A study published in Nature on July 4 by Prof. Zhu Bing from the Institute of Biophysics of the Chinese Academy of Sciences has shed light on the conserved mechanism responsible for the initiation of pericentric heterochromatin in vertebrates......»»
Study reveals human degradation of tropical forests is greater than previously estimated
Tropical forests are essential to sustain high biodiversity and mitigate climate change. They suffer from deforestation, the cutting and converting of forests for agriculture, mining, or infrastructure purposes. However, significant human impacts on.....»»
Study finds ways to enhance transcription factor activity
Transcription factors regulate gene expression by binding specific sequences on DNA, which is an essential step to producing messenger RNAs from protein-coding genes. Denes Hnisz's lab, in collaboration with Martin Vingron's lab at the MPIMG, has dis.....»»
New theory reveals fracture mechanism in soft materials
A new theory has finally deciphered the physical mechanisms of fracture in soft materials. This discovery could soon lead to new, defect-free materials that are more resistant and durable as well as environmentally friendly. The article "Elastic inst.....»»
Study highlights tension between Canada"s climate and housing goals
Canada cannot simultaneously meet its targets for emission reductions and new housing unless there's a drastic change in construction practices, according to research from the University of Toronto's Faculty of Applied Science & Engineering......»»
Veteran Apple hardware engineer departs to join Rivian
A long-time Apple hardware engineer is departing the company. As first spotted by RivianTrackr, Jeff Alves is leaving Apple after more than a decade to join Rivian, where he will join the automaker’s battery engineering team. more….....»»
Shear genius: Researchers find way to scale up wonder material, which could do wonders for the Earth
Researchers at the University of Virginia School of Engineering and Applied Science have figured out how to take a miracle material, one capable of extracting value from captured carbon dioxide, and do what no one else has: make it practical to fabri.....»»
Researchers uncover protein SRSF1"s uncommon ability to bind and unfold RNA G-quadruplexes
RNA transcription is the genomic process in which a cell produces a duplicate of a gene's DNA sequence. In a study published in Nucleic Acids Research, University of Alabama at Birmingham Department of Chemistry Professor Jun Zhang, Ph.D., and his te.....»»
New modified CRISPR protein can fit inside virus used for gene therapy
Researchers have developed a novel version of a key CRISPR gene-editing protein that shows efficient editing activity and is small enough to be packaged within a non-pathogenic virus that can deliver it to target cells. Hongjian Wang and colleagues a.....»»
Simulations demonstrate potential mechanisms of intermediate-mass black hole formation in globular clusters
Joint research led by Michiko Fujii of the University of Tokyo demonstrates a possible formation mechanism of intermediate-mass black holes in globular clusters, star clusters that could contain tens of thousands or even millions of tightly packed st.....»»
Nanoscale engineering brings light-twisting materials to more extreme settings
Imaging the hot turbulence of aircraft propulsion systems may now be possible with sturdy sheets of composite materials that twist light beams, according to research led by the University of Michigan and Air Force Research Laboratory......»»
Understanding how zwitterionic polymers can lead to safer drugs and disease prevention
Proteins are vital biomolecules responsible for performing various functions in the human body and are thus regarded as the workhorses of a cell. The primary structure of a protein is composed of different amino acids coming together. The structure s.....»»
Researchers apply quantum computing methods to protein structure prediction
Researchers from Cleveland Clinic and IBM have recently published findings in the Journal of Chemical Theory and Computation that could lay the groundwork for applying quantum computing methods to protein structure prediction......»»
Insect frass becomes food for protein-rich microalgae
As the demand for protein-rich food increases with population growth and rising awareness of nutrition and health, traditional animal and plant-based protein sources that require arable land or freshwater put significant pressure on land and resource.....»»
A new Hungarian method may aid protein research
In a paper recently published in Nature Communications, the HUN-REN-ELTE Protein Modeling Research Group (Institute of Chemistry) has laid the foundations for a mathematical method, allowing the computer-assisted comparison of the three-dimensional s.....»»
How fraudsters stole $37 million from Coinbase Pro users
A convincing phishing page and some over-the-phone social engineering allowed a group of crooks to steal over $37 million from unlucky Coinbase Pro users. One of them – Chirag Tomar, a 30-year-old citizen of the Republic of India – has be.....»»
Scientists elucidate substrate recognition and proton coupling mechanism of transporter protein VMAT2
Vesicular monoamine transporter 2 (VMAT2) is the only transporter protein in the central nervous system that mediates the storage of monoamine neurotransmitters. It plays a critical role in mediating nerve impulse transmission and neuroprotection......»»
DNA repair mechanism further elucidated in cryo-electron microscopy experiment
Researchers have discovered how the protein XPD detects severe DNA damage and controls its repair......»»