Class II PI3K lipid kinase: Structure of novel antithrombotic drug target resolved
Phosphatidylinositol 3-kinase, or PI3K for short, is a family of lipid kinases that plays a key role in the human body, performing functions such as cell division, metabolism, and cell growth......»»
Scientists propose drug-free method to combat antibiotic-resistant bacteria
Recent estimates indicate that deadly antibiotic-resistant infections will rapidly escalate over the next quarter century. More than 1 million people died from drug-resistant infections each year from 1990 to 2021, a recent study reported, with new p.....»»
Topological defects can trigger a transformation from insulating to conductive behavior in Mott materials
Researchers at Università Cattolica, Brescia campus, have discovered that the transition from insulating to conductive behavior in certain materials is driven by topological defects in the structure......»»
Gladiator II features a naval battle held in the Colosseum. These brutal spectacles really happened
It's one of the most thrilling sequences in Ridley Scott's new film Gladiator II, the long-awaited sequel to the 2000 Oscar-winning blockbuster......»»
Mathematical approach can predict crystal structure in hours instead of months
Researchers at New York University have devised a mathematical approach to predict the structures of crystals—a critical step in developing many medicines and electronic devices—in a matter of hours using only a laptop, a process that previously.....»»
Study finds private equity targets firms with earnings myopia
What makes private equity firms target a publicly traded company for takeover? A new study from the University of Iowa published in the journal Review of Accounting Studies finds that private equity is often likely to target firms that more aggressiv.....»»
Rue Valley puts a time loop spin on Disco Elysium
Rue Valley is the latest video game to utilize a time loop hook, applying that structure to a Disco Elysium-like RPG......»»
Child-centered research shows how schools can provide support for domestic abuse situations
While no official source collects data on children affected by domestic abuse, research suggests as many as 1 in 5 children experience domestic abuse in their lives. This equates to around six children in an average U.K. class size of 30 pupils. Educ.....»»
Metal-organic framework materials to remove dye contaminants for cleaner water
The future of MOFs, metal-organic framework materials, looks bright. A review in the International Journal of Environment and Waste Management has looked at how a specific class of these sponge-like materials might find increasing use in removing dye.....»»
Is a Xumo TV worth it?
Last week, Xumo announced that it’s bringing a 55- and 65-inch TV to Target for $250 and $360, respectively, both from manufacturer Hisense. While neither of these TVs are new to the world (Hisense Xumo TVs have been exclusively available at Best B.....»»
M4 Mac mini review: The first redesign in years hides incredible computing power
Apple's long-overdue overhaul of the Mac mini shrinks an already great package even more, yet it still punches far above its weight class.M4 Mac miniI've owned a Mac mini since the very first G4 model. In an era of bulky towers and a G4 Cube just yea.....»»
Trump says Elon Musk will lead “DOGE,” a new Department of Government Efficiency
Musk's Department of Government Efficiency to target "massive waste and fraud." President-elect Donald Trump today announced that a new Department of Government Efficiency—or "D.....»»
AirPods Pro crackling issue target of new class-action lawsuit
A class-action lawsuit is accusing Apple of false advertising, claiming the crackling issue of the first-gen AirPods Pro go against Apple's marketing promises.AirPods ProFiled on November 1 in the United States District Court for the Northern Distric.....»»
Fine-tuning ion exchange membranes for better energy storage
Researchers at Imperial College London, supported by colleagues at a range of other institutions, have published a study in Nature that will help fine-tune a new class of ion exchange membranes. The results should make it possible to build longer las.....»»
Improved lipid-polymer nanoparticle could advance inhalable mRNA medications and vaccines
Most people don't enjoy getting shots for treatments or vaccines. So, researchers are working to create more medicines, such as those made from messenger RNA (mRNA), that can be sprayed and inhaled......»»
Most US book bans target children"s literature featuring diverse characters and authors of color
Book bans in U.S. schools and libraries during the 2021-22 school year disproportionately targeted children's books written by people of color—especially women of color—according to a peer-reviewed study we published. They also tended to feature.....»»
From pets to pests: Researchers explore new tool to fight disease-carrying insects
Arkansas researchers are testing a product commonly used to treat ticks and fleas on pets to target fly and mosquito larvae with the goal of helping reduce the spread of diseases carried by these insects......»»
EU sustainable finance framework must go further to meet Paris Climate Goals—research shows how
New research shows that the EU's sustainable finance framework urgently needs to expand and that, in its current form, the taxonomy will not meet the Paris Climate Agreement target of limiting global temperature rise to 1.5°C......»»
BeReal: The attention war on social media
During a vocational training class one morning, the teacher was discussing the possible solutions to a problem with her students when a notification signal suddenly rang out from a mobile phone. A student took his device out of his backpack, and aske.....»»
North Korean hackers use infected crypto apps to target Macs
North Korean hackers have disguised malware in seemingly harmless macOS apps using sophisticated code to bypass security checks and target unsuspecting users.Malware apps continue to target Mac usersIn a recent discovery, researchers at Jamf Threat L.....»»
New greenhouse gas projections show Colorado moving in right direction to reduce pollution
Colorado is projected to fall short of its benchmarks for reducing greenhouse gas emissions in the next five years, but a new look at progress shows that, like a person trying to lose weight for a class reunion, the state has shaved off a few more po.....»»