Chemists synthesize an antimicrobial compound from harmless chitin and selenium
RUDN chemists obtained substances with high antibacterial activity based on chitosan and selenium. One of them even outperformed common antibiotics. The results are published in Applied Biochemistry and Microbiology......»»
Chemists devise easier new method for making a common type of building block for drugs
Ring-shaped chemical structures called saturated heterocycles are found in most FDA-approved drugs but are often difficult to create. Scripps Research chemists have just developed a surprisingly easy method for making many of these sought-after compo.....»»
New strategy for assessing the applicability of reactions
Chemists often develop and optimize new chemical reactions using so-called model systems, i.e., simple, easily accessible substrates. They then use up to around 100 other substrates as examples to show that the reaction works. This demonstration of v.....»»
When an antibiotic fails: Scientists are using AI to target "sleeper" bacteria
Since the 1970s, modern antibiotic discovery has been experiencing a lull. Now the World Health Organization has declared the antimicrobial resistance crisis as one of the top 10 global public health threats......»»
Meta relaxes “incoherent” policy requiring removal of AI videos
Meta will stop removing harmless AI videos in July. Enlarge (credit: Francesco Carta fotografo | Moment) On Friday, Meta announced policy updates to stop censoring harmless AI-generated content and instead begin "labelin.....»»
Click chemistry: Research team creates 150 new compounds
Cold Spring Harbor Laboratory (CSHL) chemists have created a new collection of molecular compounds and begun testing them as potential leads in the search for new drugs. Among these molecules, they found several that show promise for development as a.....»»
Computational chemistry needs to be sustainable too, say researchers
A diverse group of computational chemists is encouraging the research community to embrace a sustainable software ecosystem. That's the message behind a perspective article published in the Journal of Chemical Theory and Computation. The authors disc.....»»
Regulatory hurdles for updating breakpoints for antimicrobial susceptibility test devices: What to know
The unique regulatory environment for the clearance and use of antimicrobial susceptibility test (AST) systems is complex in the U.S. While members of the medical microbiology community recognize the importance of updating breakpoints for clinical an.....»»
Chemists discover a key protein in how lysosomes work
Lysosomes, often reductively referred to as the "garbage disposals" of cells, play a pivotal role in our cells' digestive systems by getting rid of unwanted materials......»»
Chemists develop method to confirm mRNA vaccine stability
University at Albany researchers at the RNA Institute have developed a new method to test COVID-19 vaccine integrity that could allow anyone with basic skills in vaccine handling to detect expired vaccines quickly and effectively, without specialized.....»»
New study reveals influencers of global biogenic volatile organic compound emission trends over the last 20 years
Biogenic volatile organic compounds (BVOCs) emitted by vegetation are important precursors of ozone and secondary organic aerosols in the atmosphere, affecting air quality, clouds, and climate. However, BVOC emissions remain highly uncertain because.....»»
A closer look into cryptococcal fungal infections in pets
Allowing pets to roam outdoors can seem like harmless fun, providing them with exercise, mental stimulation, and a chance to explore......»»
New method uses enantioselective nickel catalysis to synthesize multifunctional chiral alkylboron compounds
National University of Singapore (NUS) chemists have conceived a strategy using chiral nickel catalysts to facilitate the carboboration of alkenes, generating high-value enantioenriched alkylboronic esters......»»
Not just a lodger: Novel host-guest assembly provides enhanced reactivity
By design, synthetic molecules typically have specific jobs to prevent or accelerate reactions between other molecules. To help control more complicated reactions, researchers may harness spare space in one molecule to synthesize another chemical str.....»»
Advances and challenges in understanding compound weather and climate extremes
In the context of global warming, many extremes, such as heat waves, heavy precipitation, and droughts, have become increasingly frequent and intense, as expected theoretically. Somewhat unexpectedly, these extremes have also exhibited tightened link.....»»
Shrimp waste revolution: Unlocking potent antioxidants for health and sustainability
Shrimp are renowned for their high nutritional value, offering a rich source of proteins, amino acids, omega-3 fatty acids, minerals, and vitamins, as well as chitin and carotenoids. The increasing consumption of shrimp has led to a significant rise.....»»
New computational strategy boosts the ability of drug designers to target proteins inside the membrane
Hitting targets embedded within the cell membrane has long been difficult for drug developers due to the membrane's challenging biochemical properties. Now, Scripps Research chemists have demonstrated new custom-designed proteins that can efficiently.....»»
A faster, cheaper way to synthesize diabetes and weight loss drugs like semaglutide
Semaglutide is part of the glucagon-like peptide-1 (GLP-1) receptor targeting family of peptide drugs which are mainly used to treat diabetes but are difficult and expensive to make......»»
Study reveals "considerable farmer knowledge" on aspects of antibiotics risk
A study published in CABI Agriculture and Bioscience has revealed "considerable farmer knowledge" on different aspects of antibiotics risks—including antimicrobial resistance—associated with their use on livestock in Kenya......»»
Blighia sapida: A tropical fruit with antimicrobial properties
Antimicrobial resistance (AMR) remains 1 of the top 3 global public health challenges facing humanity. Every year, 70,000 people die globally from AMR, and the threat is exacerbated by the fact that we have moved from the era of excess antibiotics to.....»»
Aroma compound found to reduce the effects of drought, improve productivity of tomato plants
Tomato plants emit a scent to resist bacterial attacks. This aroma—or volatile compound—is hexenyl butanoate (HB). A team from the Research Institute for Plant Molecular and Cellular Biology (IBMCP), a joint center of the Universitat Politècnica.....»»