Cells use concentration gradients as a compass
Biophysicists at Ludwig-Maximilians-Universitaet (LMU) in Munch have developed a new theory, which accounts for the observation that cells can perceive their own shapes, and use this information to direct the distribution of proteins inside the cell......»»
Integrating AI with super-resolution microscopy for advancements in cellular biology
In 2014, the Nobel Prize in Chemistry celebrated the breakthroughs in super-resolution microscopy, a technology that allows us to capture highly detailed images of small parts of cells using fluorescent microscopy. Despite its success, the resolution.....»»
Researchers transform captured greenhouse gases into cyclic carbonates with biomass derivatives
Carbon dioxide is the main contributor to greenhouse gas emissions, which are responsible for global warming and climate change. Direct capture of CO2 in the air is one of the solutions proposed to reduce its concentration in the atmosphere, but comb.....»»
Creating a C4-like vein pattern in rice by manipulating SHORT ROOT and auxin levels
C4 plants are distinguished by a unique leaf structure known as Kranz anatomy, characterized by inner vascular bundle sheath cells and outer mesophyll cells. This specialized arrangement confers C4 plants with several advantages over C3 plants, inclu.....»»
Researchers discover a mechanism that controls the identity of stem cells
Researchers at the University of California, Irvine, discovered a mechanism that controls the identity of stem cells. When this mechanism fails, embryonic stem cells revert back in time and become totipotent......»»
Novel insights into antibody aggregation expected to open up new avenues for research and therapeutic applications
Antibodies (immunoglobulins) are Y-shaped proteins that recognize and neutralize specific pathogens. Their ability to target specific molecules or cells has made them promising candidates for future drug development. However, their light chains—par.....»»
A mathematical model connects the evolution of chickens, fish and frogs
One of the most enduring, basic questions of life is: How does it happen? For instance, in human development, how do cells self-organize into skin, muscles or bones? How do they form a brain, a finger, a spine?.....»»
Novel stem cell culture system could lead to future therapies for a variety of disorders
A new study led by UT Southwestern Medical Center molecular biologists presents a novel culture system to grow both embryonic and extraembryonic stem cells, potentially providing important insights into the genesis of congenital malformations and ear.....»»
Study identifies key ingredient for affordable fuel cell catalysts
To make fuel cells more affordable, researchers have spent decades searching for low-cost catalysts to replace platinum and other expensive metals......»»
Jeep Renegade leaving U.S., Canada
U.S. sales of the Renegade, Jeep's least expensive vehicle, have declined every year since 2016. The Compass, which starts at $29,995, will become the brand's new entry-level nameplate......»»
Q&A: Unveiling a new era of imaging—engineers lead breakthrough microscopy techniques
When microscopes struggle to pick up faint signals, it's like trying to spot subtle details in a painting or photograph without your glasses. For researchers, this makes it difficult to catch the small things happening in cells or other materials. In.....»»
Counteracting bone and muscle loss in microgravity
In microgravity, without the continuous load of Earth's gravity, the tissues that make up bones reshape themselves. Bone cells readjust their behaviors—the cells that build new bone slow down, while the cells that break down old or damaged bone tis.....»»
Tiny worms are helping scientists better understand fertility
Studying sex from just the male perspective misses half the experience. But much of what we know about the origins of reproductive cells comes from looking at sperm and egg formation separately—or only focusing on sperm......»»
Research reveals clever dosage control mechanism of biallelic genes
Have you ever wondered why we carry two copies of each chromosome in all of our cells? During reproduction, we receive one from each of our parents. This means that we also receive two copies, or alleles, of each gene—one allele per chromosome or p.....»»
Nanodiamonds can block tumor metastasis in mice, study shows
Nanodiamonds are 2–8 nm carbon nanoparticles, which can be easily functionalized with various chemical groups like carboxylic groups or drugs. Previous research has shown that actively dividing cells are more likely to absorb nanodiamonds and that.....»»
LIBRA: An adaptative integrative tool for paired single-cell multi-omics data
Single-cell multi-omics technologies allow a profound system-level biology understanding of cells and tissues. However, an integrative and possibly systems-based analysis capturing the different modalities is challenging. In response, bioinformatics.....»»
Cell fate choice during adult regeneration is highly disorganized, study finds
A team of scientists at the Whitehead Institute for Biomedical Research and MIT has spatially mapped the choices stem cells make during tissue regeneration in flatworms, revealing an unexpected finding: Rather than being organized into homogeneous ne.....»»
Reprogramming tissue mechanically to promote wound healing
Researchers at PSI and ETH Zurich have taken connective tissue cells that have been mechanically reprogrammed to resemble stem cells and transplanted them into damaged skin. In their laboratory experiment, they were able to show that this can promote.....»»
Malfunction in spermatogenesis: Researchers uncover contribution of cylicin proteins to male fertility
For successful fertilization, sperm should move forward rapidly and be shaped correctly. The unique structure of the sperm cells forms during spermiogenesis. Now, researchers from the University Hospital Bonn (UKB) and the Transdisciplinary Research.....»»
Unlocking the secrets of peptide sequences in cells with AI
Machine learning is now helping researchers analyze the makeup of unfamiliar cells, which could lead to more personalized medicine in the treatment of cancer and other serious diseases......»»
Researchers triple carbon nanotube yield for LEDs, solar cells, flexible and transparent electronics
Skoltech scientists have found a way to improve the most widely used technology for producing single-walled carbon nanotube films—a promising material for solar cells, LEDs, flexible and transparent electronics, smart textiles, medical imaging, tox.....»»