Can the three-dimensional organization of the T cell genome regulate (auto)immunity?
The research team of Associate Professor Charalampos G. Spilianakis, an affiliated Professor at the Institute of Molecular Biology and Biotechnology of FORTH, has been working on determining whether the three-dimensional organization of the T cell ge.....»»
Silencing in action: How cells "repress" genomic remnants of ancient viruses
Researchers have identified key cellular control sites that regulate gene expression and prevent the activation of "cryptic" genomic regions, including ancient viral sequences......»»
Meet the Advocates and Researchers Revolutionizing Sickle Cell Care
These sickle cell researchers and advocates are driving change from labs to global stages, transforming lives in the process......»»
New Sickle Cell Treatments Reach Patients after Years of Effort
The FDA recently approved three sickle cell drugs, and dozens more are in development.....»»
Researchers Seek New Solutions to Ease Sickle Cell’s Extreme Pain
Sickle cell disease causes severe pain that’s hard to treat, but researchers are finding new ways to offer relief.....»»
A Global Initiative to Advance Sickle Cell Research Could Benefit Millions
Increased funding and new public health policies for sickle cell research are needed to ease the burden on low-income nations and improve patient care.....»»
People Living with Sickle Cell Disease Share Their Experiences
Life expectancy for people with sickle cell in the U.S. has increased to about 50 years, but some people with the disease still face stigma and other barriers in health care.....»»
New Hope for Treating People with Sickle Cell Disease
Improving sickle cell care by expanding treatment options, advancing new therapies and amplifying the voices of people with the disease.....»»
New Sickle Cell Treatments Highlight the Power of Patient Perspectives
Illuminating the experience of people living with sickle cell could improve patients’ lives and enhance all of medicine.....»»
Going Back to the Moon, Researching Chickadee Hybrids and Understanding Addiction
This month’s issue covers the reasons it’s so hard to go back to the moon, the science of empathy and new advances in treating sickle cell disease.....»»
What Is Sickle Cell Disease?
You have around 35 trillion red blood cells moving around your body at all times. Typically they are rounded and flexible. What happens when they aren’t?.....»»
Tiny robots and AI algorithms could help to craft material solutions for cleaner environments
Many human activities release pollutants into the air, water and soil. These harmful chemicals threaten the health of both people and the ecosystem. According to the World Health Organization, air pollution causes an estimated 4.2 million deaths annu.....»»
Scientists decipher the energy patterns in our cells
Our cells harness energy for essential functions such as division, wound healing, and our immune response to diseases including cancer. But until now, the mechanics of how that energy affects cell behavior—and how this relates to health outcomes—.....»»
Scientists from 33 European countries join forces to generate reference genomes for the continent"s biological diversity
In a new publication, the European Reference Genome Atlas (ERGA) announces the success of its pilot project. This initiative assembled a large collaborative network of scientists and institutions across 33 countries to produce high-quality reference.....»»
Volkswagen dropping in-house U.S. auto loans, giving business to Wells Fargo
Volkswagen will cease to write U.S. Audi and VW auto loans through its in-house captive finance company and instead refer that business to Wells Fargo starting in April. It will also start to refer U.S. Ducati motorcycle loans to Wells Fargo at some.....»»
Optogenetic control reveals collective cell behavior
New research led by the Institute for Bioengineering of Catalonia (IBEC) has studied the migratory movement of groups of cells using light control. The results show that there is no leader cell that directs the collective movement, as previously thou.....»»
Scientists discover how TGF-Beta sends its message even while tethered to the cell membrane
For years, scientists have thought that TGF-Beta, a signaling protein that holds sway over an astonishing array of cellular processes from embryonic development to cancer, could only do its work once it escaped a lasso-like "straitjacket.".....»»
Modified nano-sized cell particles found to boost cancer immunotherapy, reduce side effects
Immunotherapy is a type of cancer treatment that uses the body's own immune system to help fight cancer. This is by stimulating the immune response to recognize and attack cancer cells more effectively. The treatment involves using substances that bo.....»»
Beyond displays: Liquid crystals in motion mimic biological systems
Liquid crystals are all around us, from cell phone screens and video game consoles to car dashboards and medical devices. Run an electric current through liquid crystal displays (LCDs) and they generate colors, thanks to the unique properties of thes.....»»
Ethics of biobanking for conservation: Researchers adjust ethical assessment tool for the use of genome research banks
In the face of the global biodiversity crisis, more and more biobanks are being set up to safeguard and potentially restore genetic diversity. Preserved tissue or cells allow scientists and conservationists to overcome spatial and even temporal fragm.....»»
Researchers simulate novel metal-filtered VCSEL modal control
A study led by researchers from the Changchun Institute of Optics, Fine Mechanics and Physics of the Chinese Academy of Sciences revealed a novel metal-dielectric film mode filter structure that can flexibly regulate transverse modes in vertical-cavi.....»»