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Biogen dumps dubious Alzheimer’s drug after profit-killing FDA scandal

The move ends a long saga that "ended up doing a lot of actual damage." Enlarge / The exterior of the headquarters of biotechnology company Biogen in Cambridge, Massachusetts. (credit: Getty | Boston Globe) Biotechnolog.....»»

Category: topSource:  arstechnicaFeb 1st, 2024

A shortcut for drug discovery: Novel method predicts on a large scale how small molecules interact with proteins

For most human proteins, there are no small molecules known to bind them chemically (so-called "ligands"). Ligands frequently represent important starting points for drug development but this knowledge gap critically hampers the development of novel.....»»

Category: topSource:  physorgRelated NewsApr 25th, 2024

Study presents strategy to stamp out illicit market for cannabis amid wave of policy shifts in North America

It's been five years since Canada stepped into the forefront of cannabis legalization, setting a significant precedent in the realm of drug policy. With Canada and 24 US states now embracing recreational cannabis, the battle against the illegal marke.....»»

Category: topSource:  physorgRelated NewsApr 25th, 2024

Asbury Q1 net income slips 19%; $4.2 billion in revenue sets record

Asbury Automotive Group produced $147.1 million in net income during the first quarter, down 19 percent from a year earlier as falling profit margins offset rising vehicle sales and revenue......»»

Category: topSource:  autonewsRelated NewsApr 25th, 2024

Hyundai doubles down on hybrids after Q1 profit slips 2.4%

After posting a 2.4 percent drop in quarterly profit, Hyundai said it will continue to expand its electrified model lineups globally by introducing more hybrids and new Ioniq models......»»

Category: topSource:  theglobeandmailRelated NewsApr 25th, 2024

Lithia Q1 net income down 28% as "normalization" returns to profit per vehicle

Lithia Motors said it sold 188,119 new and used vehicles, with gross profit per vehicle dropping 22% to $4,346 in the first quarter......»»

Category: topSource:  autonewsRelated NewsApr 24th, 2024

New method could cut waste from drug production

Scientists have developed a sustainable new way of making complex molecules, which could greatly reduce waste produced during drug manufacturing, a study suggests......»»

Category: topSource:  physorgRelated NewsApr 24th, 2024

Study recommends ending use of drug dogs, reducing police presence at future Mardi Gras

A study of policing at WorldPride and Mardi Gras events in 2023 found it was heavy-handed and damaging to its relationship with the LGBTQIA+ community......»»

Category: topSource:  physorgRelated NewsApr 24th, 2024

Imaging technique shows new details of peptide structures

A new imaging technique developed by engineers at Washington University in St. Louis can give scientists a much closer look at fibril assemblies—stacks of peptides that include amyloid beta, most notably associated with Alzheimer's disease......»»

Category: topSource:  physorgRelated NewsApr 24th, 2024

Tesla profits drop 55% as Elon Musk dodges cheap car questions

Tesla spent $1 billion on GPUs even as its profit margins shrank by half. Enlarge / Tesla shares rose by almost 11 percent in premarket trading despite the disastrous financial results. (credit: CFOTO/Future Publishing via Getty.....»»

Category: topSource:  arstechnicaRelated NewsApr 24th, 2024

Lithia Q1 net income down 28% as margins slip

Lithia Motors said it sold 188,119 new and used vehicles with a gross profit of $4,346 in the first quarter......»»

Category: topSource:  autonewsRelated NewsApr 24th, 2024

Fragments of bird flu virus genome found in pasteurized milk, FDA says

The test cannot tell if the virus is live. The FDA still assess milk supply as safe. Enlarge / Cows being milked (credit: Getty | Edwin Remsberg) The Food and Drug Administration on Tuesday announced that genetic fragmen.....»»

Category: topSource:  arstechnicaRelated NewsApr 24th, 2024

New toolkit makes molecular dynamics simulations more accessible

Molecular dynamics (MD) simulations have become a powerful tool in the ever-growing fields of molecular biology and drug development. While many MD simulation techniques exist, parallel cascade selection MD (PaCS-MD) is a particularly useful one when.....»»

Category: topSource:  physorgRelated NewsApr 23rd, 2024

Apple Arcade is about fun, not profit, says exec in charge

Apple executive Alex Rofman says Apple Arcade was not set up to make the company money, but also insists that game developers are getting an income.Apple ArcadeApple Arcade launched in 2019, and was then included in the Apple One bundle in 2020. Toda.....»»

Category: appleSource:  appleinsiderRelated NewsApr 23rd, 2024

GM posts higher Q1 profit, ups 2024 financial guidance

GM said it raised its full-year earnings guidance and set a first-quarter record for North American revenue......»»

Category: topSource:  autonewsRelated NewsApr 23rd, 2024

Home Assistant has a new foundation and a goal to become a consumer brand

Can a non-profit foundation get Home Assistant to the point of Home Depot boxes? Enlarge (credit: Open Home Foundation) Home Assistant, until recently, has been a wide-ranging and hard-to-define project. The open smart h.....»»

Category: topSource:  arstechnicaRelated NewsApr 22nd, 2024

After 48 years, Zilog is killing the classic standalone Z80 microprocessor chip

Z80 powered Game Boy, ZX Spectrum, Pac-Man, and a 1970s PC standard based on CP/M. Enlarge / A cropped portion of a ca. 1980 ad for the Microsoft Z80 SoftCard, which allowed Apple II users to run the CP/M operating system. (credi.....»»

Category: topSource:  arstechnicaRelated NewsApr 22nd, 2024

Home Assistant’s new foundation focused on “privacy, choice, and sustainability”

Can a non-profit foundation get Home Assistant to the point of Home Depot boxes? Enlarge (credit: Open Home Foundation) Home Assistant, until recently, has been a wide-ranging and hard-to-define project. The open smart h.....»»

Category: topSource:  arstechnicaRelated NewsApr 22nd, 2024

Nissan cuts profit and sales outlook on sliding volume, overly optimistic plans

Nissan issues a profit warning, cutting profit and sales forecasts, as volume misses expectations and the automaker compensates suppliers for its over-optimistic plans.....»»

Category: topSource:  autonewsRelated NewsApr 19th, 2024

Struggling Nissan cuts profit and sales outlook on sliding volume, over-optimistic plans

Nissan issues a profit warning, cutting profit and sales forecasts, as volume misses expectations and the automaker compensates suppliers for its over-optimistic plans.....»»

Category: topSource:  autonewsRelated NewsApr 19th, 2024

The 31 best Netflix drama shows right now (April 2024)

The best Netflix drama shows include Black Sails, Killing Eve, One Day, The Resident, The Gentlemen, Madam Secretary, The Blacklist, and many others......»»

Category: topSource:  digitaltrendsRelated NewsApr 18th, 2024