All wound up: A reversible molecular whirligig
Over the last few decades, researchers have built minuscule molecular machines that rotate or shuttle other molecules. However, it's difficult to determine the mechanical work and forces that these tiny contraptions produce, which is important when u.....»»
Molecular medicine review reveals the role of IGF in cancer, other proliferative diseases
Studies suggest that Insulin-Like Growth Factor (IGF) plays a central role in pathological growth of proliferative conditions like cancer, and may function as a resistance mechanism adopted by the majority of solid cancers following therapeutic targe.....»»
Hyundai dealership customer shot by employee in Ohio, police say
Police said the customer was found with a gunshot wound to the upper leg in the parking lot of Hyundai of Bedford in Ohio......»»
Customer shot by employee at Ohio Hyundai dealership
Police said the customer was found with a gunshot wound to the upper leg in the parking lot of Hyundai of Bedford in Ohio......»»
Small molecules, giant (surface) potential
In a molecular feat akin to getting pedestrians in a scramble crosswalk to spontaneously start walking in step, researchers at Kyushu University have created a series of molecules that tend to face the same direction to form a "giant surface potentia.....»»
Researchers reveal structure and function of a molecular motor
Molecular motors are complex devices composed of many different parts that consume energy to perform various cellular activities. In short, molecular machines transform energy into useful work. Understanding the mechanistical aspects underlying these.....»»
Using molecular simulations to study self-assembling "associating polymers"
When plastic materials are processed or recycled, their fundamental properties can degrade due to damage caused by deformation. Recycling processes tend to break molecular bonds inside the materials, making them weaker and less durable. One way that.....»»
Exploring how cells can be strong at the right place and time
Researchers from TU Delft and NWO institute AMOLF discovered how certain molecular bonds make living cells both flexible, in order to move, as well as strong, in order to withstand forces. Paradoxically, it turns out that these force-sensitive catch.....»»
Bioinspired molecular dyes for biomedical fluorescent imaging
Fluorescence imaging can be conducted with long Stokes shift dyes that minimize crosstalk between the excitation source and fluorescent emission to improve the signal-to-background ratio. Regardless, researchers still form simple, small molecule dyes.....»»
New machine-learning approach facilitates molecular conformer search in complex molecules
CEST researchers developed a new machine learning approach based on a low-energy latent space (LOLS) and density functional theory (DFT) to search for molecular conformers......»»
Amplifying the radiation of molecules after excitation to improve molecular laser spectroscopy
Sensitive animal noses can sniff out trace particles, such as volatile organic compounds, in the ambient air. Humans, on the other hand, are developing innovative technologies for this purpose, such as optical spectroscopy. This uses laser light to d.....»»
Scientists unravel molecular mechanism of PIN-mediated polar auxin transport
Auxin is the most important hormone in plants. It is mainly synthesized in cotyledons, young leaves and other growing tissues, and is transported to targeted issues via polar transport to regulate plant development and growth. How is this polar auxin.....»»
The complex origins of Apiaceae and the current state of research
Recently, scientists from Nanjing Agricultural University summarized the current state of Apiaceae research, including traditional and molecular breeding practices, bioactive compounds, medicinal applications, nanotechnology, and omics research. Curr.....»»
Plant molecular geneticists discover, and begin to crack, the epigenetic code
When plants sense environmental challenges such as drought or extended periods of extreme temperatures, they instinctively reprogram their genetic material to survive and even thrive. The chemical code that triggers those changes can be deciphered an.....»»
Cells regulating blood stem cell maintenance are diverse and conserved between species
Deep molecular analysis of the bone marrow microenvironment reveals that the cells regulating blood stem cell maintenance are more diverse than expected and have features likely to be conserved between species......»»
Sugar metabolism is surprisingly conventional in cancer
For over a century, cancer cell metabolism has been viewed as something of a paradox. New work from researchers at Washington University in St. Louis shows that it might not be such an anomaly after all. The study is published Aug. 15 in Molecular Ce.....»»
Newfound Molecular Switch Signals a Thumbs-up or Thumbs-down in the Mouse Brain
This molecule tells the brain whether to put a positive or negative spin on events. Mental disorders may result when the up/down labeling goes awry.....»»
Nanoscale fluid-phase changes revealed
Millions of barrels of oil are produced daily from shale reservoirs, yet a significant amount remains untouched, trapped in molecular-sized pores on a nanoscale. Current reservoir models can't predict oil behavior or recovery at this scale, so compan.....»»
Scientists provide new insights into flowering dates in Prunus species
Recently, scientists from the French National Institute for Agriculture provided new insights into the control of flowering dates in Prunus species, paving the way for development of molecular breeding strategies......»»
Chemists achieve "molecular editing" feat
Chemists from Scripps Research and the University of California, Los Angeles, have developed methods for the precise, flexible modification of a broad class of chemical compounds called bicyclic aza-arenes, which are commonly used to build drug molec.....»»
Scientists hid encryption key for Wizard of Oz text in plastic molecules
It's "a revolutionary scientific advance in molecular data storage and cryptography." Enlarge / Scientists from the University of Texas at Austin encrypted the key to decode text of the The Wizard of Oz in polymers. (credit: S.D. Dahlh.....»»