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Activation of prodrug using protein-encased gold catalyst

As part of their efforts to devise ways to minimize the side effects of drugs for treating cancer, four RIKEN chemists have found a biocompatible way to convert compounds with low biological activity into anticancer drugs at tumors1......»»

Category: topSource:  physorgMay 18th, 2021

Climate change may lead to shifts in vital Pacific Arctic fisheries

Marine fisheries are an essential source of protein for a large part of the world's population, as well as supporting around 390 million livelihoods and an industry worth approximately US$ 141 billion, according to the UN FAO. Yet, climate change pre.....»»

Category: topSource:  physorgRelated NewsAug 1st, 2024

Electrical impedance tomography plus extracellular voltage activation technique simplifies drug screening

When developing new drugs, understanding their effects on ion channels in the body, such as the human ether-a-go-go-related gene (hERG) ion channel found in neurons and heart muscle cells, is critical. Blocking hERG channels can disrupt a normal hear.....»»

Category: topSource:  physorgRelated NewsAug 1st, 2024

How to watch Men’s Golf in the Olympics: Full schedule

Le Golf National will be the host of the men’s golf tournament at the 2024 Olympics, which get underway today. Xander Schauffele takes aim at back-to-back gold medals after winning in Tokyo, and with compatriots Scottie Scheffler, Wyndham Clark.....»»

Category: topSource:  digitaltrendsRelated NewsAug 1st, 2024

ACE-ing protein detection in single cells

Since the 1950s, researchers have used a famous method invented by Wallace Coulter known as "flow cytometry" to characterize different types of immune cells in research studies and in blood samples from human individuals. This has enabled a much deep.....»»

Category: topSource:  physorgRelated NewsJul 30th, 2024

Precise genetics: New CRISPR method enables efficient DNA modification

With the revolutionary CRISPR/Cas technology, the DNA of living organisms can be precisely altered. Using a guide RNA that recognizes a specific DNA sequence, Cas9 protein is recruited to that sequence and cuts the DNA. This targeted cut allows the D.....»»

Category: topSource:  physorgRelated NewsJul 30th, 2024

Parasite engineered to deliver therapy proteins to nerve cells

An international team of neurobiologists has developed a way to use a parasite to deliver protein therapies through the blood–brain barrier to treat nerve cell disorders. In their study published in Nature Microbiology, the group engineered the par.....»»

Category: topSource:  informationweekRelated NewsJul 30th, 2024

Developing new methods for targeted protein degradation

Northwestern Medicine scientists have developed a new, more precise method to target proteins implicated in certain types of cancer, according to a study published in Nature Chemical Biology......»»

Category: topSource:  informationweekRelated NewsJul 30th, 2024

The New Gods of Weather Can Make Rain on Demand—or So They Want You to Believe

In a gold-trimmed command center on the outskirts of Abu Dhabi, scientists are seeking to wring moisture from desert skies. But will all their extravagant cloud-seeding tech—planes that sprinkle nanomaterials, lasers that scramble the atmosphere—.....»»

Category: gadgetSource:  wiredRelated NewsJul 30th, 2024

Mass breeding of desert locusts unlocks new food source

Mass breeding of desert locusts in a controlled environment could provide a sustainable source of protein for animals and humans as well as business opportunities in Sub-Saharan Africa, researchers say......»»

Category: topSource:  physorgRelated NewsJul 29th, 2024

Avast One Gold review: the easy-to-use antivirus software

I reviewed Avast One's free and paid antivirus software plans to find out how much more you get when you subscribe......»»

Category: topSource:  digitaltrendsRelated NewsJul 26th, 2024

How to watch Women’s Soccer in the Olympics

Reigning gold medalists Canada are back to defend their women’s Olympic soccer title in Paris, but they’ll face formidable challenges from the United States, Spain, France, Japan, Australia and others. The action gets started on Thursday,.....»»

Category: topSource:  digitaltrendsRelated NewsJul 25th, 2024

"Janus" dual-atom catalyst shows enhanced performance for electrocatalytic oxygen reduction and evolution

A research team led by Prof. Yan Wensheng from the University of Science and Technology of China (USTC) has created the innovative "Janus" dual-atom catalyst (FeCo-N3O3@C) with Fe and Co atoms coordinated synergistically through an N-O bridge, which.....»»

Category: topSource:  physorgRelated NewsJul 24th, 2024

Reducing carbon dioxide to acetate with a polyaniline catalyst coated in cobalt oxide nanoparticles

Acetic acid, also known as acetate, and other products that can be developed from acetic acid are used in a variety of industries, from food production to medicine to agriculture. Currently, acetate production uses a significant amount of energy and.....»»

Category: topSource:  physorgRelated NewsJul 24th, 2024

How to watch Men’s Soccer in the Olympics: All games and streams

Though the Opening Ceremony isn’t until Friday, men’s soccer at the 2024 Summer Olympics gets underway on Wednesday, with hosts France battling Spain, Argentina, United States and other countries for gold. If you live in the United States.....»»

Category: topSource:  digitaltrendsRelated NewsJul 24th, 2024

Nature-inspired novel catalyst paves the way for efficient hydrocarbon decomposition

A research team affiliated with UNIST has developed a novel catalyst that mimics the ability of a natural enzyme to break down harmful hydrocarbons, paving the way for a more environmentally friendly and energy-efficient approach to reducing pollutio.....»»

Category: topSource:  physorgRelated NewsJul 23rd, 2024

Nanoscopic imaging aids in understanding protein, tissue preservation in ancient bones

A pilot study from North Carolina State University shows that nanoscopic 3D imaging of ancient bone not only provides further insight into the changes soft tissues undergo during fossilization, it also has potential as a fast, practical way to determ.....»»

Category: topSource:  physorgRelated NewsJul 22nd, 2024

Gold co-catalyst improves photocatalytic degradation of micropollutants, finds study

To remove micropollutants such as pesticides and trace chemicals from the environment, you need something equally small and cunning. One potential method is photocatalysis, which uses semiconducting nanomaterials powered by sunlight to adsorb toxic c.....»»

Category: topSource:  physorgRelated NewsJul 19th, 2024

Study deciphers intricate 3D structure of DNA aptamer for disease theranostics

In a study published in PNAS, a research team has resolved the first high-resolution structure of the sgc8c DNA aptamer that targets protein tyrosine kinase 7 (PTK7), engineered two optimal sgc8c variants for disease theranostics efficiently, and rev.....»»

Category: topSource:  physorgRelated NewsJul 19th, 2024

Discovery of a tRNA modification enzyme that also acts on nucleosides

The genetic information on DNA is transcribed into messenger RNA (mRNA) and translated to the amino acid sequence by transfer RNA (tRNA) on the ribosome. Modified nucleosides within RNA are involved in maintaining and regulating the protein synthesis.....»»

Category: topSource:  physorgRelated NewsJul 18th, 2024

Modular design: New insights into protein factories in human mitochondria

The "power plants" of living cells, the mitochondria, probably evolved through endosymbiosis: A bacterium migrated into a primordial cell and eventually developed into an organelle that provides the cell with energy, among other things. Mitochondria.....»»

Category: topSource:  physorgRelated NewsJul 17th, 2024