A new culprit in antibacterial resistance: Cysteine persulfide
Scientists have developed a new, highly sensitive analytical method that can detect degraded beta-lactam antibacterial agents used in the treatment of bacterial infections. With this method, researchers found that reactive sulfur species produced by.....»»
What makes a pathogen antibiotic-resistant?
Antimicrobial resistance is a story of constantly moving parts and players. With every new or tweaked antibiotic or antimicrobial drug, the targeted pathogens begin the evolutionary dance of acquiring resistance, prompting researchers to constantly d.....»»
Researchers focus on finding flaws in superbugs" armor
Recent years have seen the rise of bacterial pathogens that have developed resistance to antibiotics. One such superbug, carbapenem-resistant Acinetobacter baumannii (CRAB), kills hundreds of critically ill patients in the U.S. each year, usually in.....»»
Emerging Salmonella variety in dairy cows found to worsen antimicrobial resistance
A study of more than 5,000 Salmonella bacteria isolated over 15 years from dairy cattle samples in the Northeast reveals a significant increase in resistance to the antimicrobial medications ampicillin, florfenicol and ceftiofur......»»
Team finds novel vehicle for antibiotic resistance
Antibiotic resistance is a significant and growing medical problem worldwide. Researchers at the Marine Biological Laboratory (MBL) and collaborators have found a novel genetic arrangement that may help a common bacterium in the human gut, Bacteroide.....»»
Scientists discover 18 new species of gut microbes in search for origins of antibiotic resistance
In a paper published February 28 in Proceedings of the National Academy of Sciences (PNAS), a research team describes the discovery of 18 never-before-seen species of bacteria of the Enterococcus type that contain hundreds of new genes—findings tha.....»»
Unlocking the secrets of geraniol: A key to enhanced disease resistance in tea plants
Geraniol contributes to the floral scent of tea (Camellia sinensis) and is abundant in tea plants, yet its biosynthesis and role in stress responses remain unclear......»»
Scientists discover why ripe fruit is more susceptible to necrotrophic pathogens than unripe fruit
In a recent study published in Molecular Plant, researchers have elucidated the mechanism underlying the increased susceptibility to necrotrophs during fruit ripening and have developed a rapid strategy to improve tomato fruit resistance to necrotrop.....»»
Research confirms exogenous methyl jasmonate can enhance tomato resistance
Tomato (Solanum lycopersicum L.) is the most widely cultivated and consumed horticultural crop. At present, saline-alkali is an important abiotic stress source that affects tomato production. Exogenous methyl jasmonate (MeJA) can enhance the resistan.....»»
Unlocking the potential of protease inhibitors for enhanced pest resistance in tea plants
Protease inhibitors are a promising strategy for enhancing herbivore resistance in plants, which is crucial for addressing the significant yield losses in crops such as tea plants due to insect herbivores. Serine protease inhibitors (SERPIN) are one.....»»
The effects of primer pairs, PCR conditions, and peptide nucleic acid clamps on plant root fungal diversity assessment
Fungi are frequently found both around and within plant tissues (especially in roots) and are involved in both plant nutrient acquisition and resistance to pathogens. Thus, characterizing the diversity and composition of plant-associated fungal commu.....»»
Scientists develop rapid gene-screening platform to boost disease resistance in crops
Scientists at CSIRO, Australia's national science agency, have achieved a breakthrough in molecular plant pathology, marking a technological leap forward for breeding durable disease-resistant crops......»»
Study finds a smoking gun for the spread and evolution of antibiotic resistance
Biomedical engineers at Duke University have uncovered a key link between the spread of antibiotic resistance genes and the evolution of resistance to new drugs in certain pathogens......»»
Pharmacists propose ways to increase the activity of levofloxacin and overcome bacterial resistance
The antibacterial drug levofloxacin is used to treat pneumonia, sinusitis, genitourinary infections, and other diseases. It is included in the WHO Model List of Essential Medicines. In terms of its chemical structure, it is a third-generation fluoroq.....»»
New research helps create new antibiotic that evades bacterial resistance
Scientists at the University of Illinois Chicago and Harvard University have developed an antibiotic that could give medicine a new weapon to fight drug-resistant bacteria and the diseases they cause......»»
Fungicide resistance: A threat to the health of humans, animals and plants
Fungi can cause disease in humans, animals and plants. Every year, 1.5 million people die from fungal infections, and fungal attacks in food crops threaten food production. To protect ourselves, we have developed chemical agents—in the form of medi.....»»
Nanofiber-coated cotton bandages fight infection and speed healing
An interdisciplinary team of Cornell researchers has identified an innovative way to harness the antioxidant and antibacterial properties of the botanical compound lawsone to make nanofiber-coated cotton bandages that fight infection and help wounds.....»»
New research highlights implications of antibiotic use in human and veterinary medicine
A series of five research publications on Antimicrobial Resistance (AMR) by APC Microbiome Ireland yields new data regarding the implications of antibiotic use in early life and the effects of antibiotics in standard dry cow therapy......»»
Study finds corn genome can gang up on multiple pathogens at once
In a changing climate, corn growers must be ready for anything, including new and shifting disease dynamics. Because it's impossible to predict which damaging disease will pop up in a given year, corn with resistance to multiple diseases would be a.....»»
Researcher examines proactive change-oriented behaviors by public service providers
Although change-oriented behaviors are critical to high-quality public service delivery, encouraging employees to embrace and pursue change in the public sector is difficult. Even with sufficient job autonomy—the principal antidote to resistance to.....»»
Uncovering genetic metabolite markers associated with anthracnose resistance to blueberry fruit rot
Anthracnose fruit rot (AFR), caused by the fungal pathogen Colletotrichum fioriniae, is the most destructive and widespread fruit disease of blueberry, impacting fruit quality and yield. The reliance on fungicides prompts the need for sustainable sol.....»»