A fine-tuned gene editor that minimizes adverse consequences
The molecular tool CRISPR-Cas9 can be used to treat inherited blood disorders, but this may cause unintended genetic alterations. A team led by MDC researchers Klaus Rajewsky and Van Trung Chu has now presented an approach in Science Advances that mi.....»»
Key gene discovered for regulating rice grain length
Recently, a research team led by Professor Wu Yuejin from the Hefei Institutes of Physical Science of the Chinese Academy of Sciences, discovered a key gene that can influence rice grain length by regulating cell proliferation, the RGL2 gene. This pr.....»»
Advanced model predicts gene architecture via nucleosome position
DNA—the molecule that carries the genetic information of all living organisms—is packaged within cells in a complex manner that allows it to function efficiently. Nucleosomes facilitate DNA compaction and also play a crucial role in regulating ge.....»»
The unintended consequences of brick-and-mortar"s decline
Lately, many big retail brands have been closing physical locations, in what has become known as the "retail apocalypse." Whether the stated reason is declining revenue, or concerns related to "shrinkage" and employee safety in some cities, the impac.....»»
Nanopore technique shows transport mechanism of chaperone proteins at the single-molecule level
Proteins control most of the body's functions, and their malfunction can have severe consequences, such as neurodegenerative diseases or cancer. Therefore, cells have mechanisms in place to control protein quality......»»
X fails to avoid Australia child safety fine by arguing Twitter doesn’t exist
Elon Musk merging Twitter into X didn't absolve X from child safety fine. Elon Musk's X (formerly Twitter) remains on the hook for an approximately $400,000 fine after failing to.....»»
Sarah Paulson on why "Hold Your Breath" is "not your average horror movie"
Sarah Paulson is no stranger to horror. Here, she goes into detail with Mashable Entertainment Editor, Kristy Puchko, about why 'Hold Your Breath' hits different......»»
The 6 best earbuds to buy in 2024, just in time for Prime Big Deal Days
We've selected the best earbuds at every price point, all tested and approved by Mashable audio experts. Plus, stay tuned for Prime Big Deal Days discounts on earbuds. Best earbuds for 2024.....»»
Plants have a backup plan to pass down accurate chromosome copies
Tending a garden is hard work. Imagine it from the plants' perspective. Each relies on fine-tuned genetic processes to pass down accurate copies of chromosomes to future generations. These processes sometimes involve billions of moving parts. Even th.....»»
LEGO-inspired RNA sensors enable customizable gene control
A research team has developed an RNA-based sensor platform that can regulate gene expression in bacteria. Their findings were recently featured in the journal Advanced Science......»»
New method quantifies single-cell data"s risk of private information leakage
Access to publicly available human single-cell gene expression datasets, or scRNA-seq datasets, has significantly enhanced researchers' understanding of both complex biological systems and the etymology of various diseases. However, the increase in a.....»»
T-Mobile pays $16 million fine for three years’ worth of data breaches
Breaches in three consecutive years lead to $16M fine and new security protocols. T-Mobile has agreed to pay a $15.75 million fine and improve its security in a settlement over a.....»»
T-Mobile pays $16 million fine for three years’ worth of data breaches
Breaches in three consecutive years lead to $16M fine and new security protocols. Enlarge (credit: Getty Images | SOPA Images ) T-Mobile has agreed to pay a $15.75 million fine and improve its security in a settlement ov.....»»
Research provides new insights into role of mechanical forces in gene expression
The genome inside each of our cells is modeled by tension and torsion—due in part to the activity of proteins that compact, loop, wrap and untwist DNA—but scientists know little about how those forces affect the transcription of genes......»»
GM"s Cruise agrees to pay $1.5 million U.S. fine as part of consent order with NHTSA over crash disclosures
General Motors self-driving subsidiary Cruise and federal safety regulators have agreed to a consent order that will remain in place at least two years, federal officials said Sept. 30......»»
How a protein keeps gene clusters quiet in the cell nucleolus
In a discovery that sheds light on the complex mechanisms of gene regulation, scientists at EPFL have uncovered a critical role for the protein ZNF274 in keeping certain gene clusters turned off by anchoring them to the cell nucleolus. The study is p.....»»
How iron and metabolic constraints can aid gene discovery for photosynthesis and biofuel production
The single-cell green alga Chromochloris zofingiensis is an emerging model organism for photosynthesis and metabolism research. Previous research has shown that with the addition of glucose, Chromochloris zofingiensis shuts off photosynthesis, rerout.....»»
Why do people breach their bail? Research shows it"s not because they"re committing more crimes
In Australia and most countries, everyone is innocent until proven guilty. Because of this, keeping someone in detention before trial comes with serious legal, practical and human-rights consequences, not just for the person accused but also for thei.....»»
Cloud cover and urban structures drastically reduce sunlight in cities
Sunlight plays a crucial role in public health, affecting vitamin D synthesis and psychological well-being. Inadequate exposure to sunlight is associated with various adverse health outcomes, such as cardiovascular diseases, metabolic syndrome, depre.....»»
Naked mole-rat found to have lost infection-resistant proteins
Scientists have found that the naked mole-rat—an underground rodent that lives up to 40 years—has lost a number of CD1 functional genes. The CD1 gene family in mammals is responsible for protein synthesis that protects the body against infectious.....»»
How a butterfly invasion minimizes genetic diversity
Until a few years ago, the butterfly known as the southern small white could barely be found north of the Alps. That was before a Europe-wide invasion that brought a huge increase in the insect's distribution—at the same time as a rapid decrease in.....»»