A fine-tuned gene editor that minimizes adverse consequences
The molecular tool CRISPR-Cas9 can be used to treat inherited blood disorders, but this may cause unintended genetic alterations. A team led by MDC researchers Klaus Rajewsky and Van Trung Chu has now presented an approach in Science Advances that mi.....»»
How a protein keeps gene clusters quiet in the cell nucleolus
In a discovery that sheds light on the complex mechanisms of gene regulation, scientists at EPFL have uncovered a critical role for the protein ZNF274 in keeping certain gene clusters turned off by anchoring them to the cell nucleolus. The study is p.....»»
How iron and metabolic constraints can aid gene discovery for photosynthesis and biofuel production
The single-cell green alga Chromochloris zofingiensis is an emerging model organism for photosynthesis and metabolism research. Previous research has shown that with the addition of glucose, Chromochloris zofingiensis shuts off photosynthesis, rerout.....»»
Why do people breach their bail? Research shows it"s not because they"re committing more crimes
In Australia and most countries, everyone is innocent until proven guilty. Because of this, keeping someone in detention before trial comes with serious legal, practical and human-rights consequences, not just for the person accused but also for thei.....»»
Cloud cover and urban structures drastically reduce sunlight in cities
Sunlight plays a crucial role in public health, affecting vitamin D synthesis and psychological well-being. Inadequate exposure to sunlight is associated with various adverse health outcomes, such as cardiovascular diseases, metabolic syndrome, depre.....»»
Naked mole-rat found to have lost infection-resistant proteins
Scientists have found that the naked mole-rat—an underground rodent that lives up to 40 years—has lost a number of CD1 functional genes. The CD1 gene family in mammals is responsible for protein synthesis that protects the body against infectious.....»»
How a butterfly invasion minimizes genetic diversity
Until a few years ago, the butterfly known as the southern small white could barely be found north of the Alps. That was before a Europe-wide invasion that brought a huge increase in the insect's distribution—at the same time as a rapid decrease in.....»»
Echoes of Wisdom actually started out as a dungeon editor
The Legend of Zelda: Echoes of Wisdom is centered around a brand new feature called echoes, which began as a dungeon editor concept......»»
Tech analysts say that major Switch 2 leak is ‘genuine’
Nintendo The big questions surrounding leaks are always about where they came from and whether they’re real. The in video games concerns the , and according to trusted tech experts, they’re close to real. Digital Foundry editor Richard Le.....»»
Compact "gene scissors" enable effective genome editing, may offer future treatment of high cholesterol gene defect
CRISPR-Cas is used broadly in research and medicine to edit, insert, delete or regulate genes in organisms. TnpB is an ancestor of this well-known "gene scissors" but is much smaller and thus easier to transport into cells......»»
Can AI help save our planet?
Last year was the hottest on record. Around the world, we are witnessing more extreme events—from massive forest fires to floods to "hot tub'" ocean temperatures—with devastating consequences for human life and our planet's biodiversity......»»
NASA has a fine plan for deorbiting the ISS—unless Russia gets in the way
"If the deorbit vehicle is ready, do we go ahead and bring it home?" Enlarge / This photo of the International Space Station was captured by a crew member on a Soyuz spacecraft. (credit: NASA/Roscosmos) A little more tha.....»»
Study shows cholesterol enhances exosome-mediated RNA drug delivery
RNA interference (RNAi) technology has gradually become a cutting-edge technology for treating diseases such as genetic disorders and cancer due to its huge potential in gene expression regulation. However, the efficient delivery and safety of short.....»»
Team develops gene editing strategy for macroalgae Neopyropia
Neopyropia is an important economic macroalga and is one of the main macroalgae cultivation species in China, Japan, South Korea and other countries. As a critical juncture in the evolution of photosynthetic organisms, red algae to which Neopyropia b.....»»
Russia warns West and Ukraine of "disastrous consequences" if Kyiv moves against Belarus
Russia warns West and Ukraine of "disastrous consequences" if Kyiv moves against Belarus.....»»
iPhone 17 Air specs might barely be an upgrade over the iPhone 16, but that’s fine by me
iPhone 17 Air specs might barely be an upgrade over the iPhone 16, but that’s fine by me.....»»
Your Samsung phone could lose wireless charging if the company doesn’t pay up
A court has ruled that Samsung has infringed on wireless charging patents and will have to pay a fine if they want to keep using it. The post Your Samsung phone could lose wireless charging if the company doesn’t pay up appeared first on Phandroid......»»
Tropical cyclone intensity exacerbated by increasing depth of ocean mixed layer, finds study
Tropical cyclones can have severe consequences for both the marine and terrestrial environments, as well as the organisms and communities who inhabit them. In the oceans, there can be alterations in sea surface temperature that disrupt biological pro.....»»
Gene-based model predicts when Japan"s cherry buds awake from dormancy
Japan in spring is famous for its cherry blossoms, or sakura, which begin flowering in the southern region of Kyushu and blaze upwards to the remote north of Hokkaido. The most abundant cherry tree cultivar, Somei Yoshino, is the iconic symbol of spr.....»»
Robert Pattinson gets the crappiest immortality in trailer for Mickey 17
"Let's blow up these second-hand baloney boys." Robert Pattinson's character didn't read his contract's fine print in Mickey 17, director Bong Joon-ho's latest film. It's been five long years since director Bong Joon-ho's film Paras.....»»
Side effects of wide-scale forestation could reduce water availability by 15% in vulnerable regions
The side effects of large-scale forestation initiatives could have serious consequences for water availability, a pioneering study has found......»»