"Nanodecoy" therapy binds and neutralizes SARS-CoV-2 virus
Nanodecoys made from human lung spheroid cells (LSCs) can bind to and neutralize SARS-CoV-2, promoting viral clearance and reducing lung injury in a macaque model of COVID-19. By mimicking the receptor that the virus binds to rather than targeting th.....»»
Bird flu is causing thousands of seal deaths. Scientists aren"t sure how to slow it down
Avian influenza is killing tens of thousands of seals and sea lions in different corners of the world, disrupting ecosystems and flummoxing scientists who don't see a clear way to slow the devastating virus......»»
Lifesaving gene therapy for kids is world’s priciest drug at $4.25M
It's unclear if government and private insurance plans can cover the costs. Enlarge / A mother with her twin 6-year-old boys who have metachromatic leukodystrophy, a genetic disease that leaves them unable to move. Photo taken on.....»»
Advances and applications of nanoparticles in cancer therapy
The research team of Prof. Changyang Gong from the Department of Biotherapy, Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University has published a new review showing that rapid growth in nanoparticles as delive.....»»
Nanoparticles target multiple COVID variants through the twist in the spike protein
Teardrop-shaped particles designed to inactivate multiple strains of the SARS-CoV-2 virus could one day complement existing treatments for COVID-19, according to a new study led by researchers at the University of Michigan and Jiangnan University in.....»»
Research seeks to develop mRNA lipid nanoparticles for next-generation oral cancer tumor suppressor therapy
A study aiming to develop a lipid nanoparticles (LNP) platform for treating oral squamous cell carcinoma (OSCC) utilizing p53 mRNA was presented at the 102nd General Session of the IADR, which was held in conjunction with the 53rd Annual Meeting of t.....»»
Researchers use an edible blue-green algae to protect honey bees against viruses
Scientists at the United States Department of Agriculture (USDA)'s Agricultural Research Service (ARS) have developed an edible antiviral treatment that can be used to protect honey bees against deformed wing virus (DWV) and other viruses, according.....»»
Ebola: Scientists reveal a new way it replicates
Scientists in Canada and the U.S. have discovered a new way in which Ebola—an often deadly virus affecting people mostly in sub-Saharan Africa—reproduces in the body......»»
In vivo production of CAR-T cells using virus-mimetic fusogenic nanovesicles
Chimeric antigen receptors (CARs) are synthesized membrane proteins that enable lymphocytes to recognize and respond to the specific antigens of target cells. Despite the impressive efficacy of CAR-T cell therapy in treating B-cell lymphoma or leukem.....»»
Using adavosertib-encapsulated MOFs for p53-mutated gallbladder cancer treatment via synthetic lethality
Since the revelation of poly(ADP-ribose) polymerase (PARP) inhibitors and their remarkable results in the treatment of BRCA1/2 mutant cancers, synthetic lethality (SL) in antitumor therapy has attracted increasing attention. SL is a phenomenon in whi.....»»
Engineered MgO nanoparticles: A promising path to synergistic cartilage and bone therapy
In a recent study published in Science Advances, researchers from Nanjing Drum Tower Hospital and others have unveiled a promising approach for treating osteoarthritis (OA) using engineered magnesium oxide (MgO) nanoparticles......»»
New bioengineered protein design shows promise in fighting COVID-19
In the wake of the COVID-19 pandemic, scientists have been racing to develop effective treatments and preventatives against the virus. A recent scientific breakthrough has emerged from the work of researchers aiming to combat SARS-CoV-2, the virus re.....»»
Q&A: Bringing forest therapy indoors can improve your health
For centuries, people have found solace in walks through the forest and the practice of "forest bathing." Now, researchers at UBC are delving into the science behind this tradition to understand its benefits better and make them accessible to all......»»
Team achieves successful mass production of metalenses designed for application in the ultraviolet region
Ultraviolet rays find diverse applications in medical and health care, serving purposes such as disinfection, sterilization, and therapy. They are also used in the semiconductor industry for creating microcircuits and patterns......»»
Early experiments show Ebola-fighting potential of engineered bacteria
Since its 1976 emergence in Africa, the Ebola virus has proven an especially lethal contagion, killing roughly 50% of the people who contract it. The 2019 FDA approval of a vaccine, combined with the subsequent development of two antibody-based drugs.....»»
Researchers reveal how a virus hijacks insect sperm: May help control disease vectors and pests
A widespread bacteria called Wolbachia and a virus that it carries can cause sterility in male insects by hijacking their sperm, preventing them from fertilizing eggs of females that do not have the same combination of bacteria and virus......»»
First atom-level structure of packaged viral genome reveals new properties and dynamics
A computational model of the more than 26 million atoms in a DNA-packed viral capsid expands our understanding of virus structure and DNA dynamics, insights that could provide new research avenues and drug targets, University of Illinois Urbana-Champ.....»»
Lumpy skin disease is a threat to Australian cattle industries. We need to know how it could enter and spread
Australian authorities are on high alert amid the spread of lumpy skin disease in cattle and buffalo across South-East Asia. While Australia remains free of the disease, the virus is likely to breach our borders at some stage......»»
Lipid nanoparticles research closing in on genetic treatments for hereditary lung disease, vision loss
Researchers who work with tiny drug carriers known as lipid nanoparticles have developed a new type of material capable of reaching the lungs and the eyes, an important step toward genetic therapy for hereditary conditions like cystic fibrosis and in.....»»
Hydrogel spheres compose a microporous structure for localized mRNA delivery
In a significant leap forward in the realm of regenerative medicine, a team at the Terasaki Institute for Biomedical Innovation has introduced a pioneering approach to mRNA therapy using microspheres made of gelatin methacryloyl (GelMA)—a gelatin-b.....»»
Avian influenza virus is adapting to spread to marine mammals
The highly pathogenic avian influenza virus H5N1 has adapted to spread between birds and marine mammals, posing an immediate threat to wildlife conservation, according to a study from the University of California, Davis, and the National Institute of.....»»