Using starch as a novel drug transporter
A special type of starch could soon be used as an excipient in medicine to improve the treatment of patients. A research team from Martin Luther University Halle-Wittenberg (MLU) has discovered that it makes a suitable drug release system and has adv.....»»
Why Colombia sees legalizing drugs as the way forward—here"s what"s being proposed
Another drug war has begun in Latin America. The newly elected president of Ecuador, Daniel Noboa, has declared a state of emergency and the military is being used to tackle violence and drug trafficking in a country that is part of the transnational.....»»
How a 27-year-old busted the myth of Bitcoin’s anonymity
Once, drug dealers and money launderers saw cryptocurrency as perfectly untraceable. Enlarge (credit: Sam Rodriguez) JUST OVER A DECADE AGO, Bitcoin appeared to many of its adherents to be the crypto-anarchist holy grail.....»»
The pros and cons of oxygen mediating the performance of nickel catalysts in dry reforming of methane
Catalysis is one of the key technologies in the chemical industry and has a wide-reaching impact on various aspects of our daily lives, including plastics manufacturing, drug synthesis, and production of both fertilizers and fuels. It is estimated th.....»»
Chemists find potential new drug for photodynamic cancer therapy
A modern alternative to chemotherapy and radiotherapy is photodynamic therapy. It is used to treat cancer, skin diseases, and infectious diseases. The essence of the method is that light-sensitive substances are introduced into the blood, which accum.....»»
They Had PTSD. A Psychedelic Called Ibogaine Helped Them Get Better
Ibogaine, a plant-based psychoactive drug, drastically reduced symptoms of depression and PTSD in veterans with traumatic brain injuries......»»
Shape-shifting protein study could advance new drug development
Proteins do the heavy lifting of performing biochemical functions in our bodies by binding to metabolites or other proteins to complete tasks. To do this successfully, protein molecules often shape-shift to allow specific binding interactions that ar.....»»
Analysis of two decades" worth of antibiotic resistance shows antibiotic use is not the only driver of superbugs
For the first time, researchers have analyzed the impact of antibiotic use on the rise of treatment-resistant bacteria over the last 20 years in the UK and Norway. They show that while the increase in drug use has amplified the spread of superbugs, i.....»»
Researchers report successful synthesis of specific chiral molecules using rearrangements of simple hydrocarbons
In nature, organic molecules are either left- or right-handed, but synthesizing molecules with a specific "handedness" in a lab is hard to do. Make a drug or enzyme with the wrong "handedness," and it just won't work. Now chemists at the University o.....»»
Canada vows to defend its drug supply against Florida importation plan
Canada adds that importing its drugs will not solve America's drug pricing problems. Enlarge / A Royal Canadian Mounted Police officer stands guard outside the Senate of Canada prior to the Speech from the Throne on September 23,.....»»
Chromium found in lead-tainted fruit pouches may explain contamination
Lead chromate, an artificial coloring, has been used in other spices to conceal poor quality. Enlarge / The three recalled pouches linked to lead poisonings. (credit: FDA) The Food and Drug Administration has discovered.....»»
Crop spray could lead to mass resistance in new-generation antifungal treatments
An agricultural fungicide approved in the U.S. and currently under consideration by authorities worldwide could have a devastating effect on a new drug for one of world's deadliest infectious diseases, show University of Manchester scientists......»»
Researchers discover important membrane transport mechanism in pathogenic bacteria
Some bacterial membrane transporters work almost like freight elevators to transport substances through the cell membrane into the interior of the cell. The transporter itself spans the bacterial membrane. Like a forklift, a soluble protein outside t.....»»
Ancient Roman wine production may hold clues for battling climate change
It is no secret that the Romans were heavy wine drinkers. Estimates put the average Roman male's consumption at a liter or more of diluted wine per day. The drink was also a symbol of civilized behavior, and widely used as a drug, medicine and ritual.....»»
Big Pharma to raise US list prices of 500 drugs in January: Report
The hikes come as drug makers face new federal rules to try to drag down prices. Enlarge (credit: Getty | Bill Diodato) January is usually a big month for hiking the list prices of drugs in the US—and it looks like 202.....»»
Novel approach uses ionic liquids for diverse aptamer applications
Aptamers, nucleic acids capable of selectively binding to viruses, proteins, ions, small molecules, and various other targets, are garnering attention in drug development as potential antibody substitutes for their thermal and chemical stability as w.....»»
Oral peptides: A new era in drug development
For decades, a substantial number of proteins, vital for treating various diseases, have remained elusive to oral drug therapy. Traditional small molecules often struggle to bind to proteins with flat surfaces or require specificity for particular pr.....»»
GPCR structure: Research reveals molecular origins of function for a key drug target
Through an international collaboration, scientists at St. Jude Children's Research Hospital have leveraged data science, pharmacology and structural information to conduct an atomic-level investigation into how each amino acid in the receptor that bi.....»»
AI generates proteins with exceptional binding strengths
A new study in Nature reports an AI-driven advance in biotechnology with implications for drug development, disease detection, and environmental monitoring. Scientists at the Institute for Protein Design at the University of Washington School of Medi.....»»
New chemical method advances toward targeted RNA medicine
Targeted drugs aim to pinpoint the exact location in the body where diseased tissue is located and where the medicine is required. The manifold benefits of administering a targeted drug include heightened efficacy, as the drug is meticulously designe.....»»
Advances in nanoscale carrier-based approaches to enhance efficacy of podophyllotoxin
Podophyllotoxin (PPT), an aryltetralin-type lignan isolated from Podophyllum species, exhibits a wide range of biologic and pharmacologic activities, and mainly serves as an antiviral agent or antitumor drug in clinical applications......»»