Using starch as a novel drug transporter
A special type of starch could soon be used as an excipient in medicine to improve the treatment of patients. A research team from Martin Luther University Halle-Wittenberg (MLU) has discovered that it makes a suitable drug release system and has adv.....»»
Global collaboration discovers drug target to combat chronic lung infection
Scientists have discovered a target for the development of a drug to combat a bacterium that can cause chronic lung infection in hospitalized patients, immunocompromised individuals and people with cystic fibrosis......»»
New molecular device unlocks potential for targeted drug delivery and self-healing materials
In a new breakthrough that could revolutionize medical and material engineering, scientists have developed a first-of-its-kind molecular device that controls the release of multiple small molecules using force......»»
Drug delivery innovation: Multifunctional system based on switchable peptide-stabilized emulsions
A new study led by Prof. Meital Reches of the Hebrew University with Mr. Daniel Boas, a Ph.D. student in her group and team of collaborators, has pioneered a new drug delivery system centered on switchable peptide-stabilized emulsions......»»
New statistical-modeling workflow may help advance drug discovery and synthetic chemistry
A new automated workflow developed by scientists at Lawrence Berkeley National Laboratory (Berkeley Lab) has the potential to allow researchers to analyze the products of their reaction experiments in real time, a key capability needed for future aut.....»»
$158,000 ALS drug pulled from market after failing in large clinical trial
The drug is now unavailable to new patients; its maker to lay off 70% of employees. Enlarge (credit: Amlyx) Amylyx, the maker of a new drug to treat ALS, is pulling that drug from the market and laying off 70 percent of.....»»
He Got a Pig Kidney Transplant. Now Doctors Need to Keep It Working
Researchers think a combination of genetic edits and an experimental immunosuppressive drug could make the first pig kidney transplant a long-term success......»»
New method reveals secrets of protein interactions with potential for drug discovery
Scientists from the University of Oulu (Finland) and Texas A&M University (U.S.), have developed a new method to study how proteins interact with small ligand molecules, paving the way, for example, for faster and more efficient drug discovery......»»
New antibiotic class effective against multidrug-resistant bacteria discovered
Scientists at Uppsala University have discovered a new class of antibiotics with potent activity against multi-drug resistant bacteria, and have shown that it cures bloodstream infections in mice. The new antibiotic class is described in an article i.....»»
New synthesis platform allows for rapid cancer drug synthesis and testing
Imperial College London researchers have developed a new platform for the synthesis, analysis and testing of new compounds which may one day treat cancer. The findings are published in the journal Angewandte Chemie International Edition......»»
New single-cell analysis tech incorporates advanced fiber optics directly into microfluidic chips
Droplet microfluidics has revolutionized single-cell analysis, crucial for genomics, drug discovery, and diagnostics, by partitioning samples into nanoliter droplets for detailed cellular analysis. Yet, its broader adoption is hindered by the complex.....»»
Researchers look to rice for "clean label" ingredients
Naturally occurring polyphenols and proteins from pigmented waxy rice may help starch ingredients improve texture without any chemical modification—a change some consumers may welcome, said Ya-Jane Wang, professor of carbohydrate chemistry......»»
China has a big problem with super gonorrhea, study finds
Drug-resistant gonorrhea is a growing problem—one that doesn't heed borders. Enlarge / A billboard from the AIDS Healthcare Foundation is seen on Sunset Boulevard in Hollywood, California, on May 29, 2018, warning of a drug-res.....»»
Researchers uncover key biomolecule involved in whooping cough infection
Researchers have identified a new complex-carbohydrate biomolecule, or glycan, that plays a key role in the nasal colonization of the Bordetella bacteria responsible for whooping cough. The discovery could make it possible to create a new drug or vac.....»»
Two keys needed to crack three locks for better engineered blood vessels
Blood vessels engineered from stem cells could help solve several research and clinical problems, from potentially providing a more comprehensive platform to screen if drug candidates can cross from the blood stream into the brain to developing lab-g.....»»
High speed protein movies to aid drug design
Researchers from the University of Southampton have developed technology to help scientists observe proteins in motion. Understanding how proteins move will allow novel drugs to be designed......»»
Scientists elucidate the role of GlyT1 in anti-schizophrenia drugs
Schizophrenia is a highly disabling mental disorder, and numerous studies have shown that the hypofunction of the N-methyl-d-aspartate (NMDA) receptor is one of its pathogenic mechanisms. Glycine transporter 1 (GlyT1), a glycine transporter protein,.....»»
Lifesaving gene therapy for kids is world’s priciest drug at $4.25M
It's unclear if government and private insurance plans can cover the costs. Enlarge / A mother with her twin 6-year-old boys who have metachromatic leukodystrophy, a genetic disease that leaves them unable to move. Photo taken on.....»»
FDA approves first drug to treat yeast ear infections in dogs
The U.S. Food and Drug Administration has approved the first drug to treat yeast ear infections in dogs......»»
Space company develops centrifuge to test impact of gravity on crystalline-structured drug molecules
Kanjakha Pal and Adrian Radocea, a pair of engineers at Varda Space Industries, a company working to develop space-based drug facilities, has developed a centrifuge-based device to test the impact of gravity on crystalline-structured drug molecules a.....»»
Alzheimer"s drug fermented with help from AI and bacteria moves closer to reality
Galantamine is a common medication used by people with Alzheimer's disease and other forms of dementia around the world to treat their symptoms. Unfortunately, synthesizing the active compounds in a lab at the scale needed isn't commercially viable......»»