Uncovering how T-cells recognise the SARS-COV-2 virus spike protein
The immune system is vitally important for resolving COVID-19 when individuals are infected with the SARS-CoV-2 virus. Moreover, the vaccines that are being administered to millions of people across the globe are designed to 'pre-warn and arm' the im.....»»
Mining the microbiome: Uncovering new antibiotics inside the human gut
The average human gut contains roughly 100 trillion microbes, many of which are constantly competing for limited resources. "It's such a harsh environment," says César de la Fuente, Presidential Assistant Professor in Bioengineering and in Chemical.....»»
New method uses nanoparticles to reprogram exhausted immune cells
A novel study led by Prof. Mira Barda-Saad and her research team at the Goodman Faculty of Life Sciences at Bar-Ilan University has unveiled a novel method to rejuvenate natural killer (NK) cells in the fight against cancer. The study, published on t.....»»
Going slow is better for fast cycling: Study reveals unique replication fork behavior in pluripotent stem cells
Embryonic stem (ES) cells are pluripotent stem cells that can produce all cell types of an organism. ES cells proliferate rapidly and have been thought to experience high levels of intrinsic replication stress. However, a recent report published in E.....»»
Chloroplast genome study separates C. meiocarpa and C. oleifera to enhance tea-oil camellia breeding
A research team sequenced and analyzed the complete chloroplast genomes of C. oleifera and C. meiocarpa, uncovering significant differences that clarified their phylogenetic relationship. This study developed 17 chloroplast DNA primers for distinguis.....»»
Exploring Huntington"s disease: Researchers discover that protein aggregates poke holes in the nuclear membrane
Researchers at Utrecht University in the Netherlands have identified a new way in which the toxic protein aggregates associated with Huntington's disease may damage nerve cells and cause them to die......»»
New tool simplifies cell tracking data analysis
Studying cell migration is vital because it plays a crucial role in many biological processes, including immune response, wound healing, and cancer metastasis. Understanding how cells move and behave can lead to breakthroughs in treating diseases, de.....»»
Newly discovered protein stops DNA damage
Researchers from Western University have discovered a protein that has the never-before-seen ability to stop DNA damage in its tracks. The finding could provide the foundation for developing everything from vaccines against cancer, to crops that can.....»»
Dutch bluetongue cases accelerating: official
Cases of bluetongue, a viral disease affecting sheep and cows, have shot up in the Netherlands according to official figures published Thursday, as the virus spreads also in France and Germany......»»
Surprise finding in study of environmental bacteria could advance search for better antibiotics
In what they labeled a "surprising" finding, Johns Hopkins Medicine researchers studying bacteria from freshwater lakes and soil say they have determined a protein's essential role in maintaining the germ's shape. Because the integrity of a bacterial.....»»
Mpox outbreak is an international health emergency, WHO declares
The declaration is "the highest level of alarm under international health law." Enlarge / A negative stain electron micrograph of a mpox virus virion in human vesicular fluid. (credit: Getty | BSIP) The World Health Or.....»»
New cobalt complex triggers ferroptosis in cancer cells
In programmed cell death, certain signaling molecules initiate a kind of suicide program to cause cells to die in a controlled manner. This is an essential step to eliminate damaged cells or to control the number of cells in certain tissues, for exam.....»»
An affordable tracking microscope to democratize microorganism research
Studying the complex motility patterns of cells and microorganisms is key to understanding their behaviors and biomechanics. However, many conventional microscopes are constrained by fixed lenses and the lack of ability to track organisms over extend.....»»
Teams forge communication shortcuts across large organizations to keep information flowing
When it comes to successful organizations, communication is key. But what does successful communication look like? A new study from North Carolina State University examines communication dynamics within a successful organization, uncovering the cruci.....»»
Common equine painkiller disrupts assisted reproduction technique efficiency in mares
Researchers at the Texas A&M School of Veterinary Medicine & Biomedical Sciences (VMBS) have discovered that phenylbutazone, a non-steroidal anti-inflammatory drug (NSAID) commonly prescribed in horses, can affect the ability of a mare's egg cells—.....»»
AI, computation, and the folds of life: Supercomputers help train a software tool for the protein modeling community
Form follows function, and this is especially true for life's building blocks—proteins. The folds and shape of molecular proteins reveal their function in supporting life......»»
“Slapped cheek” virus is surging across Europe and US, CDC warns
It's often mild, but can be very dangerous in pregnancy and immunocompromised. Enlarge / A child with a "slapped cheek" rash (credit: CDC) A common seasonal respiratory virus that typically infects school-aged children i.....»»
Study finds protein reduces toxicity of graphene oxide for drug delivery
A new study has discovered ways to reduce the toxicity of graphene oxide (GO), an ultra-thin sheet of nanomaterial derived from graphite, laying the groundwork to use it as a drug delivery system......»»
Advance in stem cell therapy: New technique for manipulating stem cells opens door to novel treatments
A new technique developed by McGill researchers for mechanically manipulating stem cells could lead to new stem cell treatments, which have yet to fulfill their therapeutic potential......»»
AI-driven method enhances electron microscopy imaging capabilities of complex biological systems
Electron microscopy has enabled visualization of the intricate details inside cells. The advancement to 3D electron microscopy, known as volume EM (vEM), has further expanded this three-dimensional, nanoscale imaging capacity. However, trade-offs bet.....»»
Starvation and adhesion drive formation of keratinocyte patterns in skin, research reveals
Fingerprints are one of the best-recognized examples of pattern formation by epithelial cells. The primary cells in the epithelium are the keratinocytes, and they are known to form patterns at the microscopic and macroscopic levels. While factors aff.....»»