Supercomputer simulations reveal how protein crowding in cells impacts interactions
Supercomputer simulations by RIKEN researchers have revealed how drug binding to a protein target changes as the surrounding environment becomes more cluttered with other proteins. These simulations could help improve drug development since they shed.....»»
Study reveals flaw in long-accepted approximation used in water simulations
Computational scientists at the Department of Energy's Oak Ridge National Laboratory have published a study in the Journal of Chemical Theory and Computation that questions a long-accepted factor in simulating the molecular dynamics of water: the 2-f.....»»
Proton-lithium interactions model lays the foundation for unlocking the secrets of stellar reactions
The reactions between protons and lithium isotopes, especially lithium-6, are pivotal for several domains ranging from nuclear energy applications to astrophysics. The detailed understanding of these interactions aids in improving models for neutron.....»»
Researchers reveal how molecular roadblocks slow the breakdown of cellulose for biofuels
Cellulose, which helps give plant cell walls their rigid structure, holds promise as a renewable raw material for biofuels—if researchers can accelerate the production process. Compared to the breakdown of other biofuel materials like corn, breakin.....»»
The quantum theory of gravitation, effective field theories and strings: Past and present
Gravity is one of four fundamental interactions. The most precise description of this force is still provided by Einstein's General Theory of Relativity, published in 1915, an entirely classical theory. This description sets gravity apart from the ot.....»»
Geologists reveal mysterious and diverse volcanism in lunar Apollo Basin, Chang"e-6 landing site
The far side of the moon is a mysterious place that is never visible from the Earth. The most remarkable feature of the moon is its asymmetry between the lunar near side and far side in composition, crust thickness, and mare volcanism. Scientists hav.....»»
Discovery of structural specialization in myriapod ovaries
Elaborate observations reveal the structural specialization within an epithelial layer covering oocytes in the Japanese pill-millipede, Hyleoglomeris japonica, considered absent in Myriapoda. Comparing this result with previous descriptions suggested.....»»
Loss of large herbivores affects interactions between plants and their natural enemies, study shows
Insects and microorganisms that feed on plants, cut up leaves, modify leaf tissue or produce leaf spots and other kinds of damage, are usually known as pests and considered harmful, yet interactions between plants and their natural enemies are import.....»»
Study reveals differences in DNA folding between neurons and other brain cells, links them to cell functions
Researchers from Skoltech and their colleagues have investigated nerve cell regulation. Mounting knowledge of regulation mechanisms could enable a better understanding of how the healthy brain operates and what goes wrong in developmental and oncolog.....»»
Study sheds light on cancer cell "tug-of-war"
Understanding how cancerous cells spread from a primary tumor is important for any number of reasons, including determining the aggressiveness of the disease itself. The movement of cells into the extracellular matrix (ECM) of neighboring tissue is a.....»»
Decoding development: mRNA"s role in embryo formation
A new study at Hebrew University reveals insights into mRNA regulation during embryonic development. The study sheds light on the intricate process of mRNA regulation during embryonic development, providing novel insights into how pluripotent cells a.....»»
Materials scientists reveal pathway for designing optical materials with specialized properties
While we usually think of disorder as a bad thing, a team of materials science researchers led by Rohan Mishra, from Washington University in St. Louis, and Jayakanth Ravichandran, from the University of Southern California, have revealed that—when.....»»
Free-forming organelles help plants adapt to climate change
Plants' ability to sense light and temperature, and their ability to adapt to climate change, hinges on free-forming structures in their cells whose function was, until now, a mystery......»»
Seeing is believing: Observation of migrasomes
Migrasomes, novel organelles first reported by Professor Li Yu' s team in 2015, are vesicular structures with diameters ranging from 0.5 to 3 micrometers that form on the retraction fibers at the rear of migrating cells. These structures contain vari.....»»
Designing a novel substrate for myogenic differentiation from induced pluripotent stem cells
Since their discovery, researchers have repeatedly demonstrated the potential medical applications of differentiated cells and tissues generated from induced pluripotent stem (iPS) cells. However, a significant hurdle to real-world medical applicatio.....»»
Laboratory and natural strains of intestinal bacterium turn out to have similar mutational profiles
Understanding mutational processes in a cell offers clues to the evolution of a genome. Most actively, mutation processes are studied in human cancer cells, while other genomes are often neglected......»»
Sony Confirms Product Launch for May 15
The new Xperia launch draws near. The post Sony Confirms Product Launch for May 15 appeared first on Phandroid. Following a number of leaks which reveal some design and hardware aspects of its upcoming Xperia phones, Sony has finally confi.....»»
Rich molecular language guides tiny liquid droplet formation in cells
Peering into a biological cell reveals a bustling microscopic world. The workhorses within this realm are specialized structures called organelles that perform vital cellular functions. Curiously, some organelles defy accepted convention: Instead of.....»»
iPhone 17 Pro rumored to get 12GB of RAM
A new rumor suggests the iPhone 17 Pro, due in 2025, will increase to 12GB of RAM and have a more narrow Dynamic Island cutout.The Dynamic Island cutout could get smaller in future modelsApple won't reveal the iPhone 16 lineup until September 2024, b.....»»
New black hole visualization takes viewers beyond the brink
Ever wonder what happens when you fall into a black hole? Now, thanks to a new, immersive visualization produced on a NASA supercomputer, viewers can plunge into the event horizon, a black hole's point of no return......»»
Scientists use high pressure NMR spectroscopy to study structure of dynamic proteins
A pressure of 3,000 bar is applied to the cold shock protein B of Bacillus subtilis in a small tube in the NMR spectroscopy laboratory at the University of Konstanz. This is roughly three times the water pressure at the deepest point of the ocean. Th.....»»