Shagene A synthesis perfected for leishmaniasis treatment
Just north of Antarctica and a little east of the southern tip of South America is the Scotia Sea. Besides glimpses of an occasional iceberg, these waters offer little to tourists......»»
First artificial synthesis of tanzawaic acid B may lead the way to new antibiotics
The discovery of antibiotics in 1928 was a major turning point in the history of medicine. For the first time since the dawn of human civilization, doctors had gained access to an extremely powerful and effective tool to fight against a wide variety.....»»
Researchers identify motor complex of cell division as a promising target for anti-cancer drug design
A biologist at the University of Hawai'i at Hilo, who is doing research into the mechanisms of cell division to find clues for cancer treatment, has just published his most recent findings in the journal Science Signaling......»»
Scientists discover new structures for unique hybrid materials by altering their chemical bonds
Putting a suite of new materials synthesis and characterization methods to the test, a team of scientists from the University of Iowa and the U.S. Department of Energy's (DOE) Brookhaven National Laboratory has developed 14 organic-inorganic hybrid m.....»»
Simultaneous synthesis and fixing of covalent organic frameworks
Covalent organic frameworks (COFs) are versatile materials composed of interconnected organic molecules held together by covalent bonds. These frameworks can be constructed in two-dimensional or three-dimensional (3D) forms which possess a unique com.....»»
New treatment to tackle infections resistant to antibiotics in chickens
An innovative treatment paves the way for reducing antimicrobial resistance in the treatment of a deadly infection in chickens, according to an international team of researchers led by the University of Surrey. The groundbreaking study investigated t.....»»
Dual wavelengths of light shown to be effective against antibiotic-resistant bacterium
Scientists have combined two light wavelengths to deactivate a bacterium that is invulnerable to some of the world's most widely used antibiotics, giving hope that the regime could be adapted as a potential disinfectant treatment......»»
Aggregation-induced catalysis: Asymmetric catalysis with chiral aggregates
Asymmetric synthesis and catalysis have been actively pursued in chemical and materials sciences for some time. Increasing numbers of drugs and pesticides contain chiral structural units in their structures since drug actions require conformational m.....»»
Eli Lilly drug shown to slow Alzheimer’s progression
Dementia experts hail "watershed moment" after trial results for donanemab antibody treatment. Enlarge / Alzheimer’s patient brain scans, provided by Eli Lilly. The US company has reported full findings of its phase 3 clinical.....»»
Scientists presents a one-step laser synthesis method for fabricating wideband microwave absorption metamaterial
Scientists from Chinese Academy of Sciences Ningbo Institute of Materials Technology and Engineering, National Physical Laboratory (U.K.), The University of Manchester (U.K.) and National University of Singapore have developed a new approach, publish.....»»
Click chemistry as a connection tool: Grand opportunities and challenges
Click chemistry could help to synthesize a variety of molecules quickly and reliably by piecing together small units. In particular, it emphasizes the development of new combinatorial chemistry methods based on the synthesis of carbon-heteroatomic bo.....»»
New target for antibiotics promises treatment for multi-drug resistant superbugs
The World Health Organization lists bacteria that are resistant to antibiotics as one of the top 10 global health threats. Therefore, researchers are looking for new antibiotics to counter this resistance. Adéla Melcrová, biophysicist at the Univer.....»»
Doctors on Bikes Prevented a Humanitarian Catastrophe in Ukraine
When Russia invaded, Ukraine’s HIV/Aids sufferers faced losing access to lifesaving treatment. Volunteers took enormous risks to keep the supplies moving......»»
We drive a gilded lily: The 2024 Mercedes-AMG EQE SUV
The AMG treatment is overkill for this electric vehicle. Enlarge / A new grille and wheels are the key giveaway that this is an AMG EQE SUV. (credit: Jonathan Gitlin) Mercedes-Benz provided a flight from DC to San Diego.....»»
Study presents new database linking RNA editing and blood cell differentiation
The process of converting DNA to proteins through an RNA is far from straightforward. Of the several types of RNA involved in the process of protein synthesis, a few may be edited mid-way. In mammals, RNA editing mostly involves converting adenosine.....»»
DNA-repair protein complex is a shapeshifter, reconfiguring itself to meet the demands of each task
Transcription factor IIH, or TFIIH, pronounced "TF two H," is a veritable workhorse among the protein complexes that control human cell activity. It plays critical roles both in transcription—the highly regulated enzymatic synthesis of RNA from a D.....»»
SuFEx as a new generation of click chemistry: Synthesis and development of linkers
Organosulfur(VI) fluoride compounds display excellent chemical stability, and yet can efficiently realize diverse linkages via the activation of specific conditions. Based on its unique nature, Sharpless, Dong and coworkers introduced SuFEx as a new.....»»
Microbial predators cause seasonal fluctuations in wastewater treatment, study shows
A community of microbial predators influences the composition of the bacterial community in wastewater. This explains seasonal variations in the microbial community that affect the efficiency of water treatment. This is the result of a study conducte.....»»
Sustainability: New catalyst makes chemical processes more efficient and less harmful to the environment
A new discovery by the Politecnico di Milano opens up new perspectives in the field of sustainable chemical synthesis, promoting innovative solutions that allow chemicals to be created in a more efficient and environmentally friendly way. The researc.....»»
Beamline innovation could enhance the potential of cancer treatment with proton therapy
Physicists have devised a way to achieve higher doses and shorter treatment times for cancer patients undergoing radiotherapy with protons, circumventing the problems of internal organ motions. They achieve this using a modification in the beamline,.....»»
Study offers strategy for green synthesis of 15N-amino acids
15N isotope-labeled amino acids (15N-amino acids) provide a safe and effective tracer tool for studying the synthesis of natural products, protein metabolism, and disease diagnosis and treatment in living organisms. In addition, it is an important sy.....»»