RNA modification: Mechanisms and therapeutic targets
RNA modifications are dynamic and reversible chemical modifications on substrate RNA that regulate mRNA stability, translation, and localization. This review is designed by Dr. Junhong Han and written by his postdoctoral researcher Dr. Lei Qiu and P.....»»
Study reveals key molecular mechanisms involved in development of tomato plant
In an article published in the journal Development, researchers at the University of São Paulo's Luiz de Queiroz College of Agriculture (ESALQ-USP) in Brazil describe mechanisms relating to the development of the tomato plant (Solanum lycopersicum).....»»
Climate change likely to drive more floods in some parts of the US, fewer in others
By breaking down flooding analysis into its main physical mechanisms, researchers at Princeton have projected that climate change will markedly impact river basin flooding across the United States during the 21st century......»»
Accessing the bronze tomato"s enhanced antioxidant and health properties through metabolic engineering
The Bronze tomato, a product of metabolic engineering, produces high levels of polyphenol due to the over-expression of genes such as VvStSy, AmDel/Rosea1, and AtMYB12. This modification, part of broader efforts to enhance plant nutritional value thr.....»»
Protein structures signal fresh targets for anticancer drugs
Cell replication in our bodies is triggered by a cascade of molecular signals transmitted between proteins. Compounds that block these signals when they run amok show potential as cancer drugs......»»
Fisker targets 50 franchised dealers in U.S., Canada
The EV maker is targeting 50 franchised dealerships in the U.S. and Canada to replace its direct-sales model......»»
Research finds climate-dependent dispersal limitation plays an important role in mountain soil microbiome
Microbial communities are highly diverse, yet the mechanisms underlying microbial community assembly are not well understood. In 1967, Daniel Janzen hypothesized that low climatic variability along elevational gradients results in greater constraints.....»»
Novel approach uses ionic liquids for diverse aptamer applications
Aptamers, nucleic acids capable of selectively binding to viruses, proteins, ions, small molecules, and various other targets, are garnering attention in drug development as potential antibody substitutes for their thermal and chemical stability as w.....»»
Novel switch turns genes on/off on cue, a promising step toward safer gene therapy
Just like a doctor adjusts the dose of a medication to the patient's needs, the expression of therapeutic genes, those modified in a person to treat or cure a disease via gene therapy, also needs to be maintained within a therapeutic window. Staying.....»»
Uncovering how tiny plastics threaten our soil and health
In a study published online in Eco-Environment & Health, researchers from Zhejiang Shuren University and China Agricultural University have delved into the interaction of tiny plastics and soil, aiming to provide insights into the mechanisms and impl.....»»
New crystalline sponge method proposed for undergraduate courses
The crystal sponge technology is a revolutionary technique, which enables the direct and precise determination of the molecular structure of liquid and gas targets. The technique uses a special network complex to selectively absorb liquid or gas targ.....»»
Breakthrough in nitrile activation is promising pathway for anticancer precursor synthesis
A research team, affiliated with UNIST has unveiled a novel method to produce a selective anticancer precursor substance that targets and eliminates cancer cells. This groundbreaking method, previously existing only in theory, has now been experiment.....»»
Novel path of intercellular signal sharing discovered in zebrafish experiments
Researchers at the University of Exeter, U.K., have discovered intricate mechanisms of ligand–receptor complex transport via specialized protrusions transporting signaling components between cells, challenging the conventional understanding of cell.....»»
Researchers identify key mechanisms, novel materials for biologically inspired information processing
Every search engine query, every AI-generated text and developments such as autonomous driving: In the age of artificial intelligence (AI) and big data, computers and data centers consume a lot of energy. By contrast, the human brain is far more ener.....»»
Viruses as important factors driving the diel dynamics of marine bacterioplankton
The diel cycle is one of the most common periodic patterns in marine ecosystems. Previously, the diel rhythm changes of marine bacterioplankton have often been attributed to factors like bacterial light-dependent physiological mechanisms or their int.....»»
Researchers develop self-assembling, self-illuminating therapeutic proteins
When it comes to delivering drugs to the body, a major challenge is ensuring that they remain in the area they're treating and continuing to deliver their payload accurately. While major strides have been made in delivering drugs, monitoring them is.....»»
Protein allows poison dart frogs to accumulate toxins safely, shows study
Scientists have identified the protein that helps poison dart frogs safely accumulate their namesake toxins, according to a study published today in eLife. The findings solve a long-standing scientific mystery and may suggest potential therapeutic st.....»»
Canada ZEV sales mandate, including incentives to build infrastructure, released
The targets begin for the 2026 model year, with a requirement that at least 20 percent of new light-duty vehicles offered for sale in that year be ZEVs. They tick upward from there, culminating with 100 percent of sales being of the zero-emissions va.....»»
Plant metabolism proves more complicated than previously understood
Plants have evolved fiendishly complicated metabolic networks. For years, scientists focused on how plants make secondary metabolites, the compounds that plants produce to enhance their defense and survival mechanisms......»»
Photodynamic action weakens resistance to antibiotics in bacteria that attack airways
The development of antibiotics to combat multidrug-resistant bacteria, especially those that infect the airways, has been increasingly tricky, and some scientists have opted to try to weaken the bacteria so that the available therapeutic substances a.....»»
If a tree burns in Canada"s unmanaged forest, does anyone count the carbon?
Earlier this fall, a commentary in the journal Communications Earth & Environment argued for a change to the implementation of the Paris Agreement's reporting mechanisms. The authors called for all countries to report carbon emissions and removals ta.....»»