Proteins let cells remember how well their last division went
Scientists find a "mitotic stopwatch" that lets individual cells remember something. Enlarge (credit: Martin Barraud) When we talk about memories in biology, we tend to focus on the brain and the storage of information i.....»»
Study uncovers the secret of long-lived stem cells
Nothing lives forever, but compared to other cells in the body, hematopoietic stem cells (HSCs) are remarkably long-lived. HSCs are blood-forming cells—they give rise to rapidly dividing progenitor cells, which in turn generate hundreds of billions.....»»
Researchers suggest that mechanical pressure triggers a key event in HIV infection
It has been more than 40 years since the beginning of the HIV/AIDS epidemic and scientists still don't fully understand how HIV enters and replicates in human cells, which has hindered the development of treatments......»»
CFO: AutoNation Finance should break even by 2025
AutoNation CFO Thomas Szlosek said that AutoNation Finance is making steady progress as the division continues shift to company customers......»»
AutoNation Finance should break even by 2025: CFO
AutoNation CFO Thomas Szlosek said that AutoNation Finance is making steady progress as the division continues shift to company customers......»»
Scientists" research on RNA editing illuminates possible lifesaving treatments for genetic diseases
A team at Montana State University published research this month that shows how RNA, the close chemical cousin to DNA, can be edited using CRISPRs. The work reveals a new process in human cells that has potential for treating a wide variety of geneti.....»»
Microgravity-grown crystals reveal new insights into protein structures
Biochemists have long been working around a blind spot when it comes to proteins. They know that hydrogen constitutes nearly half of the atoms in proteins, but how they contribute to protein function in these complex structures has been less clear. H.....»»
Cartilage healing discovery in animal models could lead to new human therapies
Researchers hope their discovery about the healing properties of fetal cartilage cells in mice will lay the groundwork for new treatments for human growth disorders and degenerative diseases......»»
Researchers decipher how an enzyme modifies the genetic material in the cell nucleus
Inside the cell nucleus, the DNA molecule is found in a densely packed DNA-protein complex known as chromatin. Here the DNA is wrapped around a core of histone proteins and densely packed to form nucleosomes. The structure of the nucleosomes determin.....»»
A systematic review of three key sugar metabolism proteins: HXK, SnRK1 and TOR
Sugar signaling is one of the most important regulatory signals for plant growth and development, and its metabolic network contains many regulatory factors. Sugar signaling molecules regulate cellular activities and organismal development by interac.....»»
A shortcut for drug discovery: Novel method predicts on a large scale how small molecules interact with proteins
For most human proteins, there are no small molecules known to bind them chemically (so-called "ligands"). Ligands frequently represent important starting points for drug development but this knowledge gap critically hampers the development of novel.....»»
Study reveals protein"s key role in helping cilium transmit signals to the rest of the cell
The essential role played by a protein in the functioning of cells is revealed in new work from the laboratory of Université de Montréal medical professor Frédéric Charron, holder of the Canada Research Chair in Developmental Neurobiology......»»
Scientists regenerate neural pathways in mice with cells from rats
Two independent research teams have successfully regenerated mouse brain circuits in mice using neurons grown from rat stem cells. Both studies, published April 25 in the journal Cell, offer valuable insights into how brain tissue forms and present n.....»»
IRIS beamline at BESSY II gets a new nanospectroscopy end station
The IRIS infrared beamline at the BESSY II storage ring now offers a fourth option for characterizing materials, cells and even molecules on different length scales. The team has extended the IRIS beamline with an end station for nanospectroscopy and.....»»
Study suggests that cells possess a hidden communication system
Cells constantly navigate a dynamic environment, facing ever-changing conditions and challenges. But how do cells swiftly adapt to these environmental fluctuations?.....»»
A shade closer to more efficient organic photovoltaics
Transparent solar cells will transform the look of infrastructure by enabling many more surfaces to become solar panels. Now, materials called non-fullerene acceptors that can intrinsically generate charges when exposed to sunlight could make semitra.....»»
Unveiling the mysteries of cell division in embryos with timelapse photography
The beginning of life is shrouded in mystery. While the intricate dynamics of mitosis are well-studied in the so-called somatic cells—the cells that have a specialized function, like skin and muscle cells—they remain elusive in the first cells of.....»»
Biomolecular condensates: Study reveals poor predictive power of established liquid-liquid phase separation assays
Cells buzz with millions of different biomolecules that diffuse chaotically through their substructures, yet they manage to ensure exquisite functional and spatial specificity......»»
Scientists study lipids cell by cell, making new cancer research possible
Imagine being able to look inside a single cancer cell and see how it communicates with its neighbors. Scientists are celebrating a new technique that lets them study the fatty contents of cancer cells, one by one......»»
Researchers create artificial cells that act like living cells
In a new study published in Nature Chemistry, UNC-Chapel Hill researcher Ronit Freeman and her colleagues describe the steps they took to manipulate DNA and proteins—essential building blocks of life—to create cells that look and act like cells f.....»»
Supercomputer simulation reveals new mechanism for membrane fusion
An intricate simulation performed by UT Southwestern Medical Center researchers using one of the world's most powerful supercomputers sheds new light on how proteins called SNAREs cause biological membranes to fuse......»»