Potent trivalent inhibitors of thrombin from anticoagulation peptides in insect saliva
Thrombosis, the clogging of blood vessels, is a major cause of heart attacks and embolism. Scientists have now engineered the first inhibitors of thrombin, a protease promoting thrombosis, that is three-fold efficient. In a study published in the jou.....»»
Scientists find new ways to convert inhibitors into degraders, paving the way for future drug discoveries
Researchers have discovered ways to convert inhibitor-style targeted cancer drugs into small molecules known as degraders, which help destroy cancer-promoting proteins in cells......»»
Oxidant pollutant ozone removes mating barriers between fly species, study finds
Insect pheromones are odor molecules used for chemical communication within a species. Sex pheromones play a crucial role in the mating of many insects. Species-specific odors attract males and females of the same species. At the same time, they main.....»»
Climate change has positive and negative effects on invasive mountain pine beetles
Climate change is hampering mountain pine beetle reproduction but also appears to slightly benefit the invasive insect in other ways, new University of Alberta research shows......»»
How insect blood stops bleeding fast
Their blood equivalent, hemolymph, forms a viscoelastic fluid that covers wounds. Enlarge (credit: Weber) What if human blood turned into a sort of rubbery slime that can bounce back into a wound and stop it from bleedin.....»»
Two sex pheromone receptors for sexual communication found in the American cockroach
Sex pheromones are vital in facilitating the chemical communication that underpins insect courtship and mating behavior. Among female American cockroaches (Periplaneta americana), two key volatile sex pheromone components, periplanone-A (PA) and peri.....»»
Rusty-patched bumblebee"s struggle for survival found in its genes
A team of researchers has uncovered alarming trends in the first range-wide genetic study of an endangered bee species. The study, led by Colorado State University and published in the Journal of Insect Science, will inform conservation and recovery.....»»
Automated bioacoustics: Researchers are listening in on insects to better gauge environmental health
Recent research led by the University of Massachusetts Amherst evaluates how well machine learning can identify different insect species by their sound, from malaria-carrying mosquitoes and grain-hungry weevils to crop-pollinating bees and sap-suckin.....»»
New antibiotic class effective against multidrug-resistant bacteria discovered
Scientists at Uppsala University have discovered a new class of antibiotics with potent activity against multi-drug resistant bacteria, and have shown that it cures bloodstream infections in mice. The new antibiotic class is described in an article i.....»»
Atmospheric observations in China show rise in emissions of a potent greenhouse gas
To achieve the aspirational goal of the Paris Agreement on climate change—limiting the increase in global average surface temperature to 1.5 degrees Celsius above preindustrial levels—will require its 196 signatories to dramatically reduce their.....»»
How Spanish conquistadors, and a tiny cactus-dwelling insect, gave the world the color red
When you think about a red object, you might picture a red carpet, or the massive ruby in the Queen's crown. Indeed, Western monarchies and marketing from brands such as Christian Louboutin have cemented our association of the color red with power an.....»»
Dung dynasty: The plant boosting powers of beetle recyclers
Dung beetles, those unsung heroes of the insect world renowned for their prowess in breaking down cattle dung, have now been found to have a positive impact on plant growth......»»
Eyes open and toes out of water: How a giant water bug reached the island of Cyprus
The island of Cyprus, although considered a hotspot for biodiversity in the Mediterranean, is more famous for its beautiful sunny coasts than for its insect fauna. Nevertheless, some visitors of its highly populated beaches, with their observations a.....»»
Artificial intelligence brings a virtual fly to life
By infusing a virtual fruit fly with artificial intelligence, Janelia and Google DeepMind, scientists have created a computerized insect that can walk and fly just like the real thing......»»
Using adavosertib-encapsulated MOFs for p53-mutated gallbladder cancer treatment via synthetic lethality
Since the revelation of poly(ADP-ribose) polymerase (PARP) inhibitors and their remarkable results in the treatment of BRCA1/2 mutant cancers, synthetic lethality (SL) in antitumor therapy has attracted increasing attention. SL is a phenomenon in whi.....»»
US energy industry methane emissions are triple what government thinks, study finds
American oil and natural gas wells, pipelines and compressors are spewing three times the amount of the potent heat-trapping gas methane as the government thinks, causing $9.3 billion in yearly climate damage, a new comprehensive study calculates......»»
Shrimp waste revolution: Unlocking potent antioxidants for health and sustainability
Shrimp are renowned for their high nutritional value, offering a rich source of proteins, amino acids, omega-3 fatty acids, minerals, and vitamins, as well as chitin and carotenoids. The increasing consumption of shrimp has led to a significant rise.....»»
Future iPhones could take a picture when bent
Apple is researching ways to embed multiple cameras in the body of a "flexible" device like a folding iPhone or iPad, and allow the device to be bent to take a picture or change a setting of the embedded cameras.Apple's original patent shows a potent.....»»
Researchers reveal how a virus hijacks insect sperm: May help control disease vectors and pests
A widespread bacteria called Wolbachia and a virus that it carries can cause sterility in male insects by hijacking their sperm, preventing them from fertilizing eggs of females that do not have the same combination of bacteria and virus......»»
Study explains how a fungus can control the corn leafhopper, an extremely harmful pest
The corn leafhopper Dalbulus maidis has become a serious problem for farmers. This tiny insect is now widely distributed in the Americas, from the south of the United States to the north of Argentina. In Brazil, it uses only corn plants as hosts, and.....»»
Microbial viruses act as secret drivers of climate change, new study finds
In a new study, scientists have discovered that viruses that infect microbes contribute to climate change by playing a key role in cycling methane, a potent greenhouse gas, through the environment......»»