Nucleoside analogs for messenger RNA metabolic labeling and sequencing
High-throughput RNA-sequencing (RNA-seq) is widely used to profile global cellular gene expression and gain insights into cellular biological processes; however, effectively tracking dynamic changes in cellular mRNA expression remains a challenge. Be.....»»
YouTube tells creators to start labeling ‘realistic’ AI content
YouTube is taking steps to try to help viewers better understand if what they’re watching has been created, whether completely or in part, by generative AI......»»
Sequencing the blue whale and Etruscan shrew genomes
The blue whale genome was published in the journal Molecular Biology and Evolution, and the Etruscan shrew genome was published in the journal Scientific Data......»»
IceCube identifies seven astrophysical tau neutrino candidates
The IceCube Neutrino Observatory, a cubic-kilometer-sized neutrino telescope at the South Pole, has observed a new kind of astrophysical messenger. In a new study recently accepted for publication as an Editors' Suggestion by the journal Physical Rev.....»»
Advancing plant biology with breakthroughs in single-cell RNA sequencing
Recent breakthroughs in single-cell RNA sequencing (scRNA), such as the recently developed "RevGel-seq" method, have revolutionized plant cell analysis. This technique, independent of special instruments, streamlines processes and resolves protoplast.....»»
DomAda-FruitDet: Domain-adaptive anchor-free fruit detection model for auto labeling
In the evolving landscape of the modern fruit industry, deep learning-based fruit detection applications have become integral, facilitating tasks such as fruit yield prediction and automated picking. Despite advancements, the labor-intensive process.....»»
How cells manage their mRNA stockpile and its output
In a typical cell, genes encoded in DNA are used to make messenger RNA (mRNA), which is used to make proteins, and this process of gene expression keeps the cell running. Gene expression is regulated in each cell such that specific genes are turned o.....»»
Global meta outage: What do we know, and what was the likely cause?
Yesterday’s global meta outage seemingly took out the company’s entire network, with users unable to access Facebook, Messenger, Instagram, Threads, and Quest headsets. The outage lasted between one and two hours for most users, and while ever.....»»
Enhancing sweet cherry breeding: Insights from genotyping-by-sequencing and genome-wide association studies
Sweet cherry (Prunus avium L.) is one of the most economically important perennial fruit species growing in temperate regions. However, partly due to climate change and biological pressures from pathogens, sweet cherry production in France has been d.....»»
Deciphering the fragrance code: High-quality sequencing and analysis of the "XiangQingCai" (XQC) genome
'Vanilla' (XQC, brassica variety chinensis), a Brassica rapa subspecies chinensis, is a vital vegetable crop in the Brassicaceae family, renowned for its intense volatile fragrance. Despite the significant progress that has been made in understanding.....»»
Meta service outage causing Facebook, Messenger, Instagram, and Threads to go down
Why is the image above blurred? Regain clarity with CleanMyPhone by MacPaw — the new AI-powered cleaning app that quickly identifies and removes blurred images, screenshots, and other clutter from your device. Download it now with a free trial......»»
Scientists get dung beetles to collect DNA samples for biodiversity studies
Researchers are sequencing the DNA of wildlife using dung beetle stomach contents. Enlarge / The Manu area of Peru contains a number of ecological zones. (credit: Corey Spruit / Wikimedia Commons) Peru’s Manu Biosphere.....»»
Molecular mechanism of transmembrane bilirubin transport by human ABCC2 transporter revealed
The metabolic process of bilirubin has been a focus of medical research since the abnormal accumulation of bilirubin has been found to be associated with a variety of diseases. Bilirubin is a substance produced by the breakdown of aging or damaged re.....»»
Researcher proposes paradigm shift in enzyme biochemistry
Although you may never have heard of the cytochrome P450 superfamily of enzymes, these proteins play diverse and critical roles in humans through the metabolic processing of drugs, pesticides, fatty acids, fat-soluble vitamins, and chemical carcinoge.....»»
RNA-sequencing analysis reveals key genes behind eggplant peel variation
Anthocyanins give fruits and vegetables their red, purple, and blue colors, offering health benefits. Their biosynthesis involves specific enzymes and is regulated by the MBW complex of transcription factors. Research has linked color variations in p.....»»
Chemical labeling method provides new approach for recording cellular activities
In living cells, a vast number of transient events occur simultaneously, each of them important for a given cell in carrying out its function. The faithful recording of these transient activities is a prerequisite for a molecular understanding of lif.....»»
New method for marking neurotransmitter receptors in living animal brains
Researchers have developed a new method of labeling naïve neurotransmitter receptor proteins in living animal brains......»»
Nature"s checkup: Surveying biodiversity with environmental DNA sequencing
A thousand kilometers south of Tokyo, far into the largest ocean on Earth, lies a chain of small, volcanic islands—the Ogasawara Islands. Nature has been able to develop on its own terms here, far from both humans and the warm Kuroshio current, whi.....»»
Stabilizing mRNA vaccines for delivery to cells
Vaccines and therapies based on messenger RNA could be more readily delivered due to a non-toxic polymer that protects RNA and controls its release inside cells......»»
Genome sequencing unveils mutational impacts of radiation on mammalian cells
The recent release of the wastewater from Japan's Fukushima nuclear disaster stirred apprehension regarding the health implications of radiation exposure. Classified as a Group 1 carcinogen, ionizing radiation has long been associated with various ca.....»»
Tiny crustaceans discovered preying on live jellyfish during harsh Arctic night
In the dark and cold of the months-long polar night, food resources are limited. Some groups of marine organisms in the polar regions overcome this challenge by going into a metabolic resting state in winter, surviving on reserves accumulated during.....»»