Monoclonal antibodies may neutralize many norovirus variants
Researchers have taken a big step toward developing targeted treatments and vaccines against a family of viruses that attacks the gastrointestinal tract......»»
Researchers show neutralizing antibodies correlate with COVID protection
Antibodies produced by vaccines and infections declined at roughly similar rates. Enlarge / Illustration of antibodies (red and blue) responding to an infection with the new coronavirus SARS-CoV-2 (purple). (credit: Getty Images) From the sta.....»»
New genetic variants responsible for neurodevelopmental disorders
Researchers have revealed how variants of a gene responsible for packing and condensing genetic material present a novel cause for certain neurodevelopmental disorders......»»
Epigenetic changes drive the fate of a B cell
B cells are the immune cells responsible for creating antibodies, and most produce antibodies in response to a pathogen or a vaccine. A small subset of B cells instead spontaneously make antibodies that perform vital housekeeping functions. Understan.....»»
Sony’s PS5 DualSense controller finally gets some new colors
The PS5's Dualsense controller is finally getting some new, space-themed color variants......»»
In the blood: Which antibodies best neutralize the coronavirus in COVID-19 patients?
Blood tests to detect antibodies against SARS-CoV-2, the virus that causes COVID-19, are an important tool for diagnosing the disease, developing potential treatments, and checking vaccine efficacy. Although such tests are available, we have very lit.....»»
New vaccine blocks COVID-19 and variants, plus other coronaviruses
A potential new vaccine has proven effective in protecting monkeys and mice from a variety of coronavirus infections -- including SARS-CoV-2 as well as the original SARS-CoV-1 and related bat coronaviruses that could potentially cause the next pandem.....»»
New Studies Show Covid-19 Vaccines" Effectiveness Against Variants
CNN recently reported on "a batch" of new studies published Wednesday — with one quantifying how much immunity improves after the second dose, and others showing how well coronavirus vaccines work against new variants of the virus: The first n.....»»
Our immune systems blanket the SARS-CoV-2 spike protein with antibodies
A previously underappreciated part of the body's natural defense against SARS-CoV-2, called non-RBD-directed antibodies, actually plays a major role in combating the virus, according to a new study. That's good news for scientists designing the next.....»»
Crohn"s disease patients have specific IgG antibodies to human bacterial flagellins
Last year, researchers used a mouse model that included immune-reactive T cells from patients with Crohn's disease in a proof-of-principle demonstration that a flagellin-directed immunotherapy might provide similar benefits in patients. Now they have.....»»
Genome sequencing reveals how salmonella carves out a niche in pork production
Variants of concern (VOCs) and variants of interest (VOIs) have become familiar terms due to the current pandemic, but variants of familiar pathogens such as salmonella also present a threat to human and animal health......»»
Severe COVID-19 cases can be predicted by new test
Researchers describe a two-step prognostic test that can help predict a patient's response to infection with SARS-CoV-2. The test combines a disease risk factor score with a test for antibodies produced early in the infection. It could be administere.....»»
Prior SARS-CoV-2 infection boosts response to variants after first vaccine dose
A single dose of vaccine boosts protection against SARS-CoV-2 coronavirus variants, but only in those with previous COVID-19, a study has found......»»
Reaching "Herd Immunity" Is Unlikely in the US, Experts Now Believe
Widely circulating coronavirus variants and persistent hesitancy about vaccines will keep the goal out of reach. The virus is here to stay, but vaccinating the most vulnerable may be enough to restore normalcy. From a report: Early in the pandemic, w.....»»
Natural immunity to malaria provides clues to potential therapies
Researchers have identified how natural human antibodies can block malaria parasites from entering red blood cells, potentially indicating how new protective therapies could be developed against this globally significant disease. The research provide.....»»
Exposure to high heat neutralizes SARS-CoV-2 in less than one second, study finds
Researchers have designed an experimental system that shows exposure of SARS-CoV-2 to a very high temperature, even if applied for less than a second, can be sufficient to neutralize the virus so that it can no longer infect another human host......»»
How a SARS-CoV-2 variant sacrifices tight binding for antibody evasion
Researchers used computer modeling to reveal that one of the three mutations that make variant B.1.351 different from the original SARS-CoV-2 reduces the virus' binding to human cells -- but potentially allows it to escape some antibodies......»»
People who"ve had COVID get "enhanced" protection against variants from one vaccine dose - study
For people who have had one dose of a COVID-19 vaccine, it seems that the jab offers better protection against variants if they previously had the virus......»»
Nanobodies inhibit SARS-CoV-2 infection, including emergent variants
Australian researchers have identified neutralizing nanobodies that block the SARS-CoV-2 virus from entering cells in preclinical models......»»
SARS-CoV-2 variants from mink evade inhibition by antibodies
It has been known for about a year that minks can become infected with SARS-CoV-2. The virus had been transmitted from humans to farmed mink and mutated in infected animals. Mutations were acquired in the spike protein, which is crucial for the entry.....»»
Simulations reveal how dominant SARS-CoV-2 strain binds to host, succumbs to antibodies
Large-scale supercomputer simulations at the atomic level show that the dominant G form variant of the COVID-19-causing virus is more infectious partly because of its greater ability to readily bind to its target host receptor in the body, compared t.....»»