Metallic complexes made from cyclic molecules
In polymetallic complexes, two or more metal atoms combine with organic molecules into larger, complicated molecular structures. Such complexes are used in the development of e.g. new catalysts, molecular magnets and sensors. In the past, polymetalli.....»»
A molecular moon lander: Insight into molecular motion on surfaces at the nanoscale
For years, scientists have been intrigued by how molecules move across surfaces. The process is critical to numerous applications, including catalysis and the manufacturing of nanoscale devices......»»
Scientists find new ways to convert inhibitors into degraders, paving the way for future drug discoveries
Researchers have discovered ways to convert inhibitor-style targeted cancer drugs into small molecules known as degraders, which help destroy cancer-promoting proteins in cells......»»
Oxidant pollutant ozone removes mating barriers between fly species, study finds
Insect pheromones are odor molecules used for chemical communication within a species. Sex pheromones play a crucial role in the mating of many insects. Species-specific odors attract males and females of the same species. At the same time, they main.....»»
New molecular device unlocks potential for targeted drug delivery and self-healing materials
In a new breakthrough that could revolutionize medical and material engineering, scientists have developed a first-of-its-kind molecular device that controls the release of multiple small molecules using force......»»
A simple, inexpensive way to make carbon atoms bind together
The active ingredient in many drugs is what's known as a small molecule: bigger than water, much smaller than an antibody and mainly made of carbon. It's tough, however, to make these molecules if they require a quaternary carbon—a carbon atom bond.....»»
Click chemistry: Research team creates 150 new compounds
Cold Spring Harbor Laboratory (CSHL) chemists have created a new collection of molecular compounds and begun testing them as potential leads in the search for new drugs. Among these molecules, they found several that show promise for development as a.....»»
New research shows key molecules within nerve cells persist throughout life
After two decades in the United States, Martin Hetzer returned home to Austria in 2023 to become the 2nd President of the Institute of Science and Technology Austria (ISTA). A year into his new role, the molecular biologist remains engaged in the rea.....»»
New method reveals secrets of protein interactions with potential for drug discovery
Scientists from the University of Oulu (Finland) and Texas A&M University (U.S.), have developed a new method to study how proteins interact with small ligand molecules, paving the way, for example, for faster and more efficient drug discovery......»»
Attack and defense in the microverse: How small RNA molecules regulate viral infections of bacteria
Viruses need hosts. Whether it's measles, the flu or coronavirus, viral pathogens cannot multiply or infect other organisms without the assistance of their hosts' cellular infrastructure. However, humans are not the only ones affected by viruses: ani.....»»
Researchers reveal evolutionary path of important proteins
New research from the University of Wisconsin–Madison decodes the evolutionary pathway of regulatory proteins, the molecules that help control gene expression......»»
Researchers reveal structure and assembly mechanism of unique module in cellulosome
Cellulosomes are multi-enzyme complexes known for their efficient lignocellulose degradation, which is valuable in bioenergy technique development. The diverse composition and intricate assembly of cellulosomes give them exceptional substrate degrada.....»»
Researchers challenge the limits of molecular memory, opening the door to the development of molecular chips
Some molecules respond to external light pulses by changing their structure and holding certain states that can be switched from one to another. These are commonly referred to as photoswitches and usually have two possible states. Recently, however,.....»»
Researchers invent artificial intelligence model to design new superbug-fighting antibiotics
Researchers at McMaster University and Stanford University have invented a new generative artificial intelligence model that can design billions of new antibiotic molecules that are inexpensive and easy to build in the laboratory......»»
Research reveals new starting points for the rapid and targeted development of future drugs
Many important medicines, such as antibiotics and anticancer drugs, are derived from natural products of bacteria. The enzyme complexes that produce these active ingredients have a modular design that makes them ideal tools for synthetic biology. By.....»»
Molecular crystal motors move like microbes when exposed to light
At first glance, Rabih O. Al-Kaysi's molecular motors look like the microscopic worms you'd see in a drop of pond water. But these wriggling ribbons are not alive; they're devices made from crystallized molecules that perform coordinated movements wh.....»»
How DHX9 stress granules protect daughter cells from UV-induced RNA damage
During the process of cell division, new daughter cells inherit a mix of genetic material and other molecules from their mother cells. This inheritance includes both beneficial components, which can help them for a robust start in life, and potential.....»»
Photocatalytic synthesis of arylacetic acid via C=C double bond cleavage with carbon dioxide
Alkenes represent one of the most abundant classes of organic molecules, which are available in bulk quantities from petroleum and renewable resources, with various utilization in agrochemistry, pharmacy, and organic materials. Typically, the transfo.....»»
A universal insertion of various molecules into ionic crystals under high pressure
An international team has revealed a surprising universal propensity of forming stable hybrid compounds under high pressures......»»
Not just a lodger: Novel host-guest assembly provides enhanced reactivity
By design, synthetic molecules typically have specific jobs to prevent or accelerate reactions between other molecules. To help control more complicated reactions, researchers may harness spare space in one molecule to synthesize another chemical str.....»»
Conduction of catalytic properties from buried transitional metals to exposed inert main group metals
The electronic interaction between buried single transitional metal and adjacent aluminum atoms via metallic bonding can be well demonstrated......»»