Lipid nanoparticle mRNA therapy improves survival in mouse models of maple syrup urine disease
Researchers from the University of Pennsylvania, Perelman School of Medicine, Gene Therapy Program, and Moderna, have shown that repeated administration of lipid nanoparticle-encapsulated mRNA therapy significantly extended survival and reduced serum.....»»

Newly discovered degradation process for mRNA could lead to clinical treatments
Researchers at the University of Würzburg have discovered a process that breaks down mRNA molecules in the human body particularly efficiently. This could be useful, for example, in the treatment of cancer. The study is published in Molecular Cell......»»
iPhone 17 Air could be priced lower than the Pro models
Apple is rumored to launch the iPhone 17 Air in 2025, and now the latest reports suggests it could be cheaper than the Pro models. The post iPhone 17 Air could be priced lower than the Pro models appeared first on Phandroid. Come 2025, App.....»»
How companies can address bias and privacy challenges in AI models
In this Help Net Security interview, Emre Kazim, Co-CEO of Holistic AI, discusses the need for companies to integrate responsible AI practices into their business strategies from the start. He explores how addressing issues like bias, privacy, and tr.....»»
ChatGPT o1 vs. o1-mini vs. 4o: Which should you use?
There are more than a half-dozen versions of OpenAI's various large language and reasoning models. Here's what you need to know about each to get the most out of the popular chatbot......»»
WSJ: Foldable iPhone on track for 2026; iPhone 17 Air to be cheaper than pro models
According to a new report from The Wall Street Journal this morning, Apple is working on two new foldable devices for 2026 and beyond. The report also provides some details on the rumored ultra-slim iPhone 17 model. more….....»»
Apple is fixing the laughably bad Magic Mouse charging port
The Magic Mouse is infamous for its terrible underside charging port position and poor ergonomics. Apple's next design overhaul could finally atone for the sin......»»
Report: Apple designing all new Magic Mouse, fixing charge port placement
According to the latest edition of Mark Gurman’s Power On newsletter, Apple is working on a fully redesigned , focusing on key criticisms of the existing product. more….....»»
New Magic Mouse said to fix everything that"s been wrong with it for 15 years
Apple may be working on a replacement to its venerable Magic Mouse for 2026, and the new design is said to finally kill off a major sticking point for some users.Since 2015, you've charged the Magic Mouse through a port on its baseFor most of 2023 an.....»»
Apple may discontinue current iPhone SE & iPhone 14 models in EU
If you are in the EU and were thinking of buying an iPhone SE or iPhone 14 from Apple, you might want to hurry.The iPhone SE, and remaining iPhone 14 models, may be discontinued soon.A new rumor suggests that Apple may discontinue selling the current.....»»
Huge and rare Mekong catfish spotted in Cambodia, raising conservation hopes
Six critically endangered Mekong giant catfish—one of the largest and rarest freshwater fish in the world—were caught and released recently in Cambodia, reviving hopes for the survival of the species......»»
24-inch iMac for just $799 with delivery for the holidays
Blowout prices are in effect on Apple iMacs, with discounts of up to $1,000 off and free delivery in time for Hanukkah and Christmas.Save up to $1,000 on iMacs with discount code.Save up to $1,000 on the iMac 24-inch models listed below when you appl.....»»
Deals: M4/Pro/Max MacBook Pro up to $300 off, PlugBug Find My charger new low, HomeKit lamp 30% off, more
We are indeed still tracking Wi-Fi + Cell M2 iPad Air models at $150 off alongside the $169 price drop on AirPods Max that is now available to everyone, but there are more inbound today. Firstly, as shipping windows close ahead of the holidays, today.....»»
Prices for Intel’s Arc B580 are already shooting through the roof
Intel's Arc B580 is officially out, but most models are already sold out online and scalpers are already stepping in to raise the price......»»
FuzzyAI: Open-source tool for automated LLM fuzzing
FuzzyAI is an open-source framework that helps organizations identify and address AI model vulnerabilities in cloud-hosted and in-house AI models, like guardrail bypassing and harmful output generation. FuzzyAI offers organizations a systematic appro.....»»
Are LLMs capable of non-verbal reasoning?
Processing in the "latent space" could help AI with tricky logical questions. Large language models have found great success so far by using their transformer architecture to e.....»»
More precise snowmelt forecasts thanks to high-resolution satellite data
SLF researchers have used satellite data to optimize their models, which they use to predict how much snow there is and when and where it will melt. This progress is important in order to be able to warn of floods and inundations in good time......»»
Today"s best Apple Watch sales deliver last-minute holiday deals from $189
Amazon and Best Buy are enticing shoppers to pick up last-minute holiday gifts with fresh discounts on Apple Watch models, including the Series 10 and Ultra 2.The black Apple Watch Ultra 2 has dropped in price today.New for Thursday is a steeper pric.....»»
Weight loss drugs may also treat addiction, Alzheimer’s, and heart disease
Pharmaceutical companies are already cashing in on their other health benefits. One of Dr. Mo Sarhan’s patients was experiencing intense cravings for opioids and alcohol when th.....»»
How "thirsty" trees may make forests more vulnerable to climate change
A new study suggests that increased maple populations may leave forests in western North Carolina more vulnerable to extreme weather conditions like flooding and drought......»»
Citrix acquires deviceTRUST and Strong Network
With the widespread adoption of hybrid work models, where teams operate across geographical regions on managed and unmanaged devices, every connection and endpoint presents a potential security risk. Addressing this challenge, Citrix announced the st.....»»