Key protein linked to appetite and obesity in mice
Researchers from the Okinawa Institute of Science and Technology Graduate University (OIST) have identified a protein that plays a key role in how the brain regulates appetite and metabolism. Loss of the protein, XRN1, from the forebrain, resulted in.....»»
DeepMind adds a diffusion engine to latest protein-folding software
Major under-the-hood changes let AlphaFold handle protein-DNA complexes and more. Enlarge / Prediction of the structure of a coronavirus Spike protein from a virus that causes the common cold. (credit: Google DeepMind) M.....»»
MATE transporter facilitates bitter saponin transport from cytoplasm to vacuole
Domestic soybeans serve as an important source of healthy edible plant oil and high-quality plant protein in our food culture. In addition to the well-known components of oil (approximately 20%), protein (approximately 40%), and carbohydrates (approx.....»»
A "conservation conundrum"—when rat control to conserve one species threatens another
When pest rats and mice decimate populations of native species, pest control is a no-brainer. But what if baiting rats protects threatened songbirds, while poisoning critically endangered owls?.....»»
Rising knife crime in London is linked to austerity cuts to youth services—here"s the evidence
New data released by the Office of National Statistics (ONS) shows knife and gun crime in London rose sharply in the 12 months before December 2023......»»
Nintendo vs. Garry’s Mod: Dissecting the ‘Fake’ Domain Behind All the Chaos
Facepunch Studios has confirmed that years of Nintendo-related uploads are being deleted from Steam Workshop in response to takedown notices linked to Garry's Mod. What began as rumors of a Nintendo DMCA takedown campaign, suddenly shifted towards a.....»»
How to get the best results from endoscopic sleeve gastroplasty?
The problem of obesity for many people is not only difficult because of body image problems. It is also sometimes dangerous to health and even life. For this reason, more and more people are deciding to undertake a difficult, but necessary to improve.....»»
Scientists use high pressure NMR spectroscopy to study structure of dynamic proteins
A pressure of 3,000 bar is applied to the cold shock protein B of Bacillus subtilis in a small tube in the NMR spectroscopy laboratory at the University of Konstanz. This is roughly three times the water pressure at the deepest point of the ocean. Th.....»»
Synthetic chemistry approach yields new compounds with potential biomedical applications
Researchers at Rice University have successfully synthesized a group of natural compounds known as fusicoccanes. The molecules found in various living organisms exhibit diverse biological activities, including the ability to modulate protein-protein.....»»
New discovery of a mechanism that controls cell division
Researchers at Umeå University, Sweden, have discovered that how a special protein complex called the Mediator moves along genes in DNA may have an impact on how cells divide. The discovery may be important for future research into the treatment of.....»»
Mice navigating a virtual reality environment reveal that walls, not floors, define space
New research published in Current Biology sheds light on how animals create and maintain internal spatial maps based on their surroundings......»»
Long snouts protect foxes when they dive headfirst into snow, study finds
When hunting for mice in winter, red and Arctic fox are known to plunge headfirst at speeds of 2–4 meters per second, but their sharp noses reduce the impact force in snow and protect them from injury, according to a new Cornell University study......»»
Microgravity-grown crystals reveal new insights into protein structures
Biochemists have long been working around a blind spot when it comes to proteins. They know that hydrogen constitutes nearly half of the atoms in proteins, but how they contribute to protein function in these complex structures has been less clear. H.....»»
Researchers develop tiny droplets that harness laser light to detect disease markers
A team of researchers led by Nanyang Technological University, Singapore (NTU Singapore) has created tiny droplets that, when activated by laser light, can detect viral protein biomarkers indicating the presence of certain diseases......»»
Cartilage healing discovery in animal models could lead to new human therapies
Researchers hope their discovery about the healing properties of fetal cartilage cells in mice will lay the groundwork for new treatments for human growth disorders and degenerative diseases......»»
Bacteria "nanowires" could help develop green electronics
Engineered protein filaments originally produced by bacteria have been modified by scientists to conduct electricity. In a study published recently in the journal Small, researchers revealed that protein nanowires—which were modified by adding a si.....»»
Researchers decipher how an enzyme modifies the genetic material in the cell nucleus
Inside the cell nucleus, the DNA molecule is found in a densely packed DNA-protein complex known as chromatin. Here the DNA is wrapped around a core of histone proteins and densely packed to form nucleosomes. The structure of the nucleosomes determin.....»»
Study reveals protein"s key role in helping cilium transmit signals to the rest of the cell
The essential role played by a protein in the functioning of cells is revealed in new work from the laboratory of Université de Montréal medical professor Frédéric Charron, holder of the Canada Research Chair in Developmental Neurobiology......»»
Scientists regenerate neural pathways in mice with cells from rats
Two independent research teams have successfully regenerated mouse brain circuits in mice using neurons grown from rat stem cells. Both studies, published April 25 in the journal Cell, offer valuable insights into how brain tissue forms and present n.....»»
Scientists replace fishmeal in aquaculture with microbial protein derived from soybean processing wastewater
Scientists from Nanyang Technological University, Singapore (NTU Singapore) and Temasek Polytechnic have successfully replaced half of the fishmeal protein in the diets of farmed Asian seabass with a "single cell protein" cultivated from microbes in.....»»
Congo demands that Apple prove iPhone doesn"t use conflict materials
The Democratic Republic of Congo has told Apple it believes the iPhone maker's supply chain is using materials linked to militia groups.Apple has been asked to verify that it doesn't use "conflict minerals" in the iPhoneApple and at least most Big Te.....»»