Keeping Vilsmeier reagent in the flow: From toxin to medicine in one go
The Vilsmeier reagent is necessary for producing a large range of pharmaceuticals, but its unstable nature and toxic precursor phosgene are challenges for its use. A new process that efficiently produces phosgene, the Vilsmeier reagent and the desire.....»»
Researchers study the intricacies of homologous recombination and abnormal chromosome bridges
Keeping the genetic information stored in genomic DNA intact during the cell division cycle is crucial for almost all lifeforms. Extensive DNA damage invariably causes various adverse genomic rearrangements, which can lead to cell death in the best c.....»»
Study demonstrate improved root growth in radio-cesium contaminated soil
Researchers at the RIKEN Center for Sustainable Resource Science (CSRS) have identified a way for plants to gain resistance to cesium, a radioactive toxin that can be found in contaminated soil. After manipulating a specific biological signaling path.....»»
Researchers develop a nanoparticle that can penetrate the blood-brain barrier
Researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine have developed a nanoparticle that can penetrate the blood-brain barrier. Their goal is to kill primary breast cancer tumors and brain metastase.....»»
Animal behavior research better at keeping observer bias from sneaking in—but there"s still room to improve
Animal behavior research relies on careful observation of animals. Researchers might spend months in a jungle habitat watching tropical birds mate and raise their young. They might track the rates of physical contact in cattle herds of different dens.....»»
Upwork is an essential tool for scaling your small business, here’s why
As a small business owner, Upwork is an essential tool for scaling your operations and keeping up with the biggest competitors in the market......»»
Lahar detection system upgraded for Mount Rainier
In the shadow of Washington State's Mount Rainier, about 90,000 people live in the path of a potential large lahar—a destructive, fluid and fast-moving debris flow associated with volcanic slopes......»»
Centipedes used in traditional Chinese medicine offer leads for kidney treatment
A venomous, 8-inch centipede may be the stuff of nightmares, but it could save the life of those affected by kidney disease. Researchers report in the Journal of Natural Products that the many-legged critter—used in traditional Chinese medicine—c.....»»
Developing a tech platform for fast, robust series production of nanoparticles
Nucleic acid-based medications such as mRNA vaccines offer tremendous potential for medicine and are opening up new therapeutic approaches. These active ingredients must be enclosed inside nanoparticles to ensure that they get to where they are neede.....»»
Researchers unveil single-shot and complete polarization imaging system using metasurfaces
Think of all the information we get based on how an object interacts with wavelengths of light—aka color. Color can tell us if food is safe to eat or if a piece of metal is hot. Color is an important diagnostic tool in medicine, helping practitione.....»»
Understanding cellular transcription responses to oxygen deprivation
A multiprotein complex is essential for regulating cellular responses to oxygen deprivation, a key feature of cancer, according to a Northwestern Medicine study published in the Proceedings of the National Academy of Sciences......»»
Antimicrobial peptide from cows shows potential for treating hypervirulent bacteria
University of Central Florida College of Medicine researcher Renee Fleeman is on a mission to kill drug-resistant bacteria, and her latest study has identified a therapy that can penetrate the slime that such infections use to protect themselves from.....»»
Apple confirms bug that is keeping some iPhone alarms from sounding
If your iPhone hasn't been waking you up lately, you're not alone. Enlarge / An iPhone in Standby mode, charging wirelessly on a desk. (credit: Apple) If your iPhone's alarm hasn't woken you lately, it seems you're not.....»»
NASA lays out how SpaceX will refuel Starships in low-Earth orbit
"The fundamental flow mechanism is the pressure delta across the umbilical." Enlarge / Artist's illustration of two Starships docked belly-to-belly in orbit. (credit: SpaceX) Some time next year, NASA believes SpaceX wi.....»»
Too many vehicles, slow reactions and reckless merging: New math model explains how traffic and bacteria move
What do the flow of cars on a highway and the movement of bacteria towards a food source have in common? In both cases, annoying traffic jams can form. Especially for cars, we might want to understand how to avoid them, but perhaps we've never though.....»»
Standardized power management could extend EV battery range
The automotive industry is being pushed to establish a standard to manage the power flow to electronic control units that govern different parts of the vehicle depending on the context......»»
Human activities have an intense impact on Earth"s deep subsurface fluid flow
The impact of human activities—such as greenhouse gas emissions and deforestation—on Earth's surface have been well-studied. Now, hydrology researchers from the University of Arizona have investigated how humans impact Earth's deep subsurface, a.....»»
CRISPR is promising to tackle antimicrobial resistance, but bacteria can fight back
In his presentation "How to use CRISPR-Cas to combat AMR" at the ESCMID Global Congress, Assistant Prof. Ibrahim Bitar, Department of Microbiology, Faculty of Medicine and University Hospital in Plzen, Charles University in Prague, Plzen, Czech Repub.....»»
Lyme disease in dogs: What dog owners should know
As Lyme disease cases rise in the U.S., humans are not the only ones at risk. Veterinarians with the Virginia-Maryland College of Veterinary Medicine say dogs are increasingly vulnerable to this tick-borne illness......»»
Making sustainable biotechnology a reality: Joined forces aim to improve biocatalysts
Everything biobased: plastic, medicine, and fuel. It seems like a futuristic utopia. But for how long? A collaboration of researchers now proposes an idea to accelerate the development process. By combining machine learning and laboratory automation,.....»»
Wait lines may boost perceived popularity of restaurant brands
Restaurants can benefit from keeping their customers waiting, according to a new study from researchers in the Penn State School of Hospitality Management......»»