How the pathogen Mycobacterium tuberculosis secretes and traffics its only known exotoxin
Six years ago, Michael Niederweis, Ph.D., described the first known toxin of the deadly pathogen Mycobacterium tuberculosis (Mtb), an exotoxin that had gone undetected for 132 years......»»
Study highlights "unbridled globetrotting" of the strangles pathogen in horses
In the largest ever study of its kind into an equine pathogen, scientists in 18 countries used the latest DNA sequencing techniques to track the bacteria responsible for a disease called 'strangles' in horses around the world......»»
Model may help Chincoteague ponies avoid deadly infection
Researchers from North Carolina State University have created a model that can identify potential hot spots for the pathogen Pythium insidiosum in the Chincoteague National Wildlife Refuge, home to the wild Chincoteague ponies......»»
Tracing malaria"s ecology using blood samples from birds
Malaria is the deadliest pathogen in human history. Nearly half the people on Earth are at risk of contracting the disease from the parasites that cause it. But humans aren't the only ones who can get these parasites—different forms are found in ot.....»»
Ancient DNA reveals clues about how tuberculosis shaped the human immune system
A new study employing ancient human DNA reveals how tuberculosis has affected European populations over the past 2,000 years, specifically the impact that disease has had on the human genome. This work has implications for studying not only evolution.....»»
Backyard chickens risk pathogen spread
Keeping backyard chickens was already on the rise, and the hobby has become even more popular during the COVID-19 pandemic. Now, a University of Georgia researcher cautions that the practice has risks not just for chickens, but for wildlife and peopl.....»»
Skeletons reveal humans evolved to fight pathogens
As COVID-19 impacts lives around the world—a new skeleton study is reconstructing ancient pandemics to assess human's evolutionary ability to fight off leprosy, tuberculosis and treponematoses with help from declining rates of transmission when the.....»»
Study could explain tuberculosis bacteria paradox
Tuberculosis bacteria have evolved to remember stressful encounters and react quickly to future stress, according to a study by computational bioengineers and infectious disease experts......»»
A novel gene discovery associated with a development disorder of pituitary origin
The pituitary gland is a pea-sized endocrine gland composed of two structurally and functionally separate parts known as anterior and posterior lobes. The pituitary gland's anterior lobe secretes six hormones essential to growth, reproduction, and ot.....»»
Study could explain tuberculosis bacteria paradox
Tuberculosis bacteria have evolved to remember stressful encounters and react quickly to future stress, according to a study by computational bioengineers at Rice University and infectious disease experts at Rutgers New Jersey Medical School (NJMS)......»»
Tuberculosis: New biomarker indicates individual treatment duration
The treatment of tuberculosis (TB) is long and demanding. In particular, in cases of resistant tuberculosis, the WHO generally recommends a standard treatment duration of at least 18 months, as there are no reliable biomarkers for an early terminatio.....»»
TB study reveals potential targets to treat and control infection
Researchers may have found a new pathway to treat and control tuberculosis (TB), the disease caused by Mycobacterium tuberculosis (Mtb). Using single-cell RNA sequencing (scRNAseq), a next-generation sequencing technology, scientists were able to fur.....»»
Chimp deaths at Sierra Leone sanctuary linked to a bacterium
An international team of researchers has found what they believe to be the pathogen that has been killing chimpanzees at a Sierra Leone sanctuary for approximately 15 years. In their paper published in the journal Nature Communications, the group des.....»»
Pathogen Discovered That Kills Endangered Chimps: Is It a Threat to Humans?
An Ebola outbreak and a few false leads slowed a 15-year search for bacteria that attack the nerves and gut -- Read more on ScientificAmerican.com.....»»
A novel approach to determine how carcinogenic bacteria find their targets
The gram-negative bacteria Helicobacter pylori (H. pylori) colonize the stomachs of the majority of the world's population. Although most people may never experience major complications due to the pathogen, H. pylori infections increase the risk of c.....»»
Pathogen Discovered that Kills Endangered Chimps: Is It a Threat to Humans?
An Ebola outbreak and a few false leads slowed a 15-year search for bacteria that attack the nerves and gut -- Read more on ScientificAmerican.com.....»»
Pathogen Discovered That Kills Endangered Chimps; Is It a Threat to Humans?
An Ebola outbreak and a few false leads slowed a 15-year search for bacteria that attack the nerves and gut -- Read more on ScientificAmerican.com.....»»
Bats living in Cambodia in 2010 carried "nearly identical" pathogen to COVID-19 virus, scientists discover
Bats that lived in a Cambodian cave in 2010 carried a pathogen that is "nearly identical" to the virus that causes COVID-19, scientists have discovered......»»
Researchers find inhibitors effective against a coronavirus enzyme
While the first vaccines have been developed against the pathogen SARS-CoV-2, studies are still underway to identify effective drugs for treating coronavirus infections. Scientists in Gießen, Mainz, and Würzburg in Germany involved in a fundamental.....»»
How one pathogen evades the immune system
An LMU research team led by Nicolai Siegel has uncovered a mechanism that enables the parasite that causes sleeping sickness in humans to escape the attention of the immune system. The finding may also be relevant to other infectious diseases......»»
The odd structure of ORF8: Mapping the coronavirus protein linked to disease severity
A team of HIV researchers, cellular biologists, and biophysicists who banded together to support COVID-19 science determined the atomic structure of a coronavirus protein thought to help the pathogen evade and dampen response from human immune cells......»»