Genetics: Biosynthesis pathway of a new DNA nucleobase elucidated
DNA is composed of nucleobases represented by the letters A, T, G and C. They form the basis of the genetic code and are present in all living beings. But in a bacteriophage, another base, represented by the letter Z, exists. This exception, the only.....»»
Repeated sexual failures cause social stress in fruit flies
Repeated failures to reproduce make fruit flies stressed and frustrated, which in turn makes them less resilient to other types of stress, Julia Ryvkin at Bar-Ilan University and colleagues report in PLOS Genetics......»»
Chromatin modifier-centered pathway points to higher crop yield
A team led by Prof. Song Xianjun from the Institute of Botany of the Chinese Academy of Sciences, while researching a ternary protein complex in rice nuclei that affects grain size, has shown that the transcription factor bZIP23—a protein that regu.....»»
Axiom and SpaceX are disrupting Europe’s traditional pathway to space
The program sees more countries get access to space, but the details are murky. Enlarge / A Falcon 9 rocket launches the Axiom-2 mission on May 21, 2023. (credit: SpaceX) The European Space Agency’s (ESA) has a deal wi.....»»
Breakthrough in nitrile activation is promising pathway for anticancer precursor synthesis
A research team, affiliated with UNIST has unveiled a novel method to produce a selective anticancer precursor substance that targets and eliminates cancer cells. This groundbreaking method, previously existing only in theory, has now been experiment.....»»
Artificial design and biosynthesis of a single-domain catenated dihydrofolate reductase
This study was led by Prof. Wen-Bin Zhang (College of Chemistry and Molecular Engineering, Peking University & Beijing Academy of Artificial Intelligence) and Dr. Jing Fang (College of Chemistry and Molecular Engineering, Peking University). A single.....»»
Novel molecular ionization dissociation pathway induced by Interatomic Coulombic Decay
A research group led by Prof. Ma Xinwen at the Institute of Modern Physics (IMP) of the Chinese Academy of Sciences (CAS) has observed a novel molecular ionization dissociation pathway triggered by Interatomic Coulombic Decay (ICD). The study, publis.....»»
Genetics of host plants determine what microorganisms they attract, finds study
Plants often develop communities with microorganisms in their roots, which influences plant health and development. Although the recruitment of these microbes is dictated by several factors, it is unclear whether the genetic variation in the host pla.....»»
Researchers, Coast Salish people analyze 160-year-old Indigenous dog pelt
Researchers from the Smithsonian's National Museum of Natural History led a new analysis that sheds light on the ancestry and genetics of woolly dogs, a now extinct breed of dog that was a fixture of Indigenous Coast Salish communities in the Pacific.....»»
Fifth national climate assessment emphasizes mitigation
The latest National Climate Assessment highlights historic emissions reductions and outlines new guidance for achieving a net-zero emissions pathway......»»
New understanding of ancient genetic parasite may spur medical breakthroughs
A multidisciplinary study published in Nature has elucidated the structure of the machinery responsible for writing much of our "dark genome"—the 98% of our DNA that has largely unknown biological function. These results may spur entirely novel tre.....»»
Scientists identify biosynthetic pathway of chemotherapeutic derived from yew trees
Researchers from the Max Planck Institute of Molecular Plant Physiology have unraveled the biosynthetic pathway of paclitaxel in yew plants, a chemotherapeutic for cancer treatment. This discovery might facilitate the production of this very complex.....»»
Study presents new pathway for electrochemically controlling ion selectivity
A new study by researchers at the University of Illinois Urbana-Champaign advances fundamental knowledge about the role of solvation in ion binding and presents a new pathway for electrochemically controlling ion selectivity. The study was published.....»»
Environmental stress rather than genetics influenced height differences in early Neolithic people: Study
The difference in height between female and male individuals in northern Europe during the Early Neolithic (8,000–6,000 years before present, bp) may have been influenced by cultural factors, a paper published in Nature Human Behaviour suggests. Th.....»»
Researchers elucidate how IGF2"s secretory pathway mediates muscle stem cell differentiation
A research team led by the Hong Kong University of Science and Technology (HKUST) recently revealed how TMED10, a type of transmembrane protein, regulates muscle stem cell differentiation through mediating the secretion of insulin-like growth factor.....»»
Molecular fossils study sheds light on feeding strategy shift in ancient life
Paleontologists are getting a glimpse at life over a billion years in the past based on chemical traces in ancient rocks and the genetics of living animals. Research published in Nature Communications combines geology and genetics, showing how change.....»»
MicroRNA holds clues to why some mammals are cancer-prone
Researchers at the College of Veterinary Medicine (CVM) have identified an important pathway that reveals why some mammals, like humans, dogs, and cats, regularly develop mammary cancer while others, such as horses, pigs, and cows, rarely do......»»
5,200 years of migrations from Mexico to California may be the origin of a mystery language
Research led by Nathan Nakatsuka of the Department of Genetics at Harvard Medical School, Boston, has found evidence supporting migrations into California from Mexico and the presence of Mexican-related ancestry in Central and Southern California sta.....»»
Scientists discover a new stress response pathway for repairing RNA-protein crosslinks caused by toxic aldehydes
The research team of Professor Petra Beli and their collaborators have discovered that aldehydes, a type of toxic chemical produced by the body after drinking alcohol, damage cells by creating chemical crosslinks between RNA and proteins, thereby int.....»»
Yeast engineering leads to new frontiers in jasmonate biosynthesis
A research team led by Prof. Luo Xiaozhou from the Shenzhen Institute of Advanced Technology (SIAT) of the Chinese Academy of Sciences (CAS) and Prof. Jay D. Keasling from the University of California, Berkeley, has developed an engineered yeast to p.....»»
Decoding the genetics of ascorbic acid: A deep dive into strawberry"s Vitamin C content and its environmental factors
Vitamin C, also known as ascorbic acid (AsA), is a prevalent antioxidant found in various organisms, notably plants and animals. Functionally, AsA plays a variety of roles, from enzyme cofactor to safeguarding against oxidative damage during photosyn.....»»