Converting P450 peroxygenase into peroxidase via mechanism-guided protein engineering
Enzyme catalysis is a promising green solution for producing pharmaceuticals, fine chemicals, and biofuels. However, exploring their catalytic promiscuity to expand and enhance the capabilities of enzymes remains challenging......»»
Researchers identify novel endocytic recycling mechanism with "kiss-and-run" membrane fusion
Endocytosis and recycling control the uptake and retrieval of various materials in eukaryotic cells. Mammalian cells have developed several recycling routes, including the relatively extensively studied "fast" and "slow" tubulovesicular recycling pat.....»»
How a bacterial pathogen that causes dysentery manipulates molecular activity to assure its survival
Virginia Tech researchers have learned how bacteria manipulate molecules to infect the host organism. Daniel Capelluto and his research team have discovered the mechanism by which the bacterial pathogen Shigella flexneri, the causative agent of dysen.....»»
Double-edged STING: A new pathway involved in aging
A protein called STING, previously shown to control a pathway that contributes to antiviral signaling, also plays an important role in cellular stress clearance and cell survival, according to a new paper published in Molecular Cell......»»
Plant pathogen battle: A tomato protein"s dual role in defense and susceptibility
Tomatoes, a staple crop worldwide, are increasingly threatened by biotic stressors such as viruses, fungi, and bacteria, with the effects worsening under climate change. These challenges lead to reduced yields and compromised nutritional quality, hig.....»»
New mechanism uncovered for the reduction of emu wings
.Researchers have uncovered a novel mechanism underlying the skeletal reduction and asymmetry of emu wings. Their research reveals that the absence of distal muscle formation results in a lack of mechanostress during development, leading to the obser.....»»
Template synthesis creates multilayered perovskites with unique ferroelectric behavior
A group of Nagoya University researchers in Japan has synthesized 4- and 5-layered versions of the important electrical material perovskite. Analyzing the mechanism of ferroelectricity in the material, they found it has a unique function: the materia.....»»
Harmless strain of E. coli bacteria may be able to prevent urinary tract infections
Researchers from the Texas A&M College of Veterinary Medicine and Biomedical Sciences (VMBS) and the College of Engineering are collaborating on a project that uses harmless strains of E. coli bacteria to disrupt the bacteria responsible for urinary.....»»
Greener pastures: Better ammonia production for a more sustainable future
Energy demands are at an all-time high, as is the need to be environmentally conscious. That's why chemical engineering professors Drs. Joseph Kwon and Mark Barteau have developed a strategy to predict the performance of new catalysts for greener amm.....»»
An unexpected protein connection in maize growth and defense could enhance crop resilience
Maize (corn) is one of the most important staple crops in the world and has been extensively studied. Yet, many aspects of the genetic mechanisms regulating its growth and development remain unexplored......»»
Team discovers naturally occurring DNA-protein hybrids
Thanks to a serendipitous discovery and a lot of painstaking work, scientists can now build biohybrid molecules that combine the homing powers of DNA with the broad functional repertoire of proteins—without having to synthesize them one by one, res.....»»
Scientists discover nonstomatal control of water loss in critical crops
Scientists have discovered that certain plants can survive stressful, dry conditions by controlling water loss through their leaves without relying on their usual mechanism—tiny pores known as stomata......»»
Scientists discover how TGF-Beta sends its message even while tethered to the cell membrane
For years, scientists have thought that TGF-Beta, a signaling protein that holds sway over an astonishing array of cellular processes from embryonic development to cancer, could only do its work once it escaped a lasso-like "straitjacket.".....»»
Trimetallic-based nanocarriers method shows promise for visualized idiopathic pulmonary fibrosis therapy
A research group from Ningbo Institute of Materials Technology and Engineering (NIMTE) of the Chinese Academy of Sciences (CAS) developed a novel method for idiopathic pulmonary fibrosis (IPF) therapy by transplanting mesenchymal stem cells (MSCs), w.....»»
Edible insects show promise as sustainable nutritional source
As the global population grows and traditional livestock production increasingly strains environmental resources, there is a rising interest in alternative protein sources. Edible insects, particularly grasshoppers, are abundant in regions like Camer.....»»
Want to walk in space? It might cost you more than money
A tech billionaire has become the first layperson to perform a space walk. Hundreds of miles above Earth, Jared Isaacman took part in an intricate performance of science and engineering that often comes with some serious health risks, even for profes.....»»
Aging, overworked and underfunded: NASA faces a dire future, according to experts
Aging infrastructure, short-term thinking, and ambitions that far outstrip its funding are just a few of the problems threatening the future of America's vaunted civil space agency, according to the National Academies of Sciences, Engineering, and Me.....»»
Studies on pigeon-guided missiles, swimming abilities of dead fish among Ig Nobles winners
A study that explores the feasibility of using pigeons to guide missiles and one that looks at the swimming abilities of dead fish were among the winners Thursday of this year's Ig Nobels, the prize for comical scientific achievement......»»
Dual-feedback mechanism can enhance anti-oxidation coatings in fiber composites
Fiber-reinforced ceramic matrix composites (CMCs) have been the primary choice for radome materials in hypersonic vehicles due to their high toughness, strength, and other advantageous properties. However, oxidation by oxygen in the atmospheric envir.....»»
Floquet engineering tunes ultracold molecule interactions and produces two-axis twisting dynamics
The interactions between quantum spins underlie some of the universe's most interesting phenomena, such as superconductors and magnets. However, physicists have difficulty engineering controllable systems in the lab that replicate these interactions......»»
Researchers aim to control gene expression by studying the memories of cells
Communication between cells is now believed to activate a memory mechanism that sustains gene expression, a finding based on the work of Dr. Gregory Reeves......»»