Biosynthesis pathway of a new DNA nucleobase elucidated
DNA is composed of nucleobases represented by the letters A, T, G and C. They form the basis of the genetic code and are present in all living beings. But in a bacteriophage, another base, represented by the letter Z, exists. This exception, the only.....»»
Scientists reveal novel double-roaming mechanism in chemical reaction
Roaming, a novel mechanism in reaction dynamics, describes an unusual pathway that is quite different from the conventional minimum-energy path. It is facilitated by the initial frustrated dissociation to form radical products, and then the meanderin.....»»
Out of thick air: Transforming carbon dioxide into light-emitting carbon
A team of researchers at the University of Ottawa has found a way to use visible light to transform carbon dioxide gas, or CO2, into solid carbon forms that emit light. This development creates a new, low-energy CO2 reduction pathway to solid carbon.....»»
‘It’s almost like placing an IV’: Brain monitoring electrode receives FDA 510(k) clearance
An FDA pathway that’s greased the gears for COVID-19 vaccines and drugs has paved the way for something else: a new take on electroencephalography (EEG), the established brain-monitoring technique in which metallic electrodes are placed on the scal.....»»
Genome mining leads to a new type of peptide prenylation
Researchers from NUS used a genome mining approach to identify a new cyclic peptide (tolypamide) derived from a cyanobacterium. The biosynthesis of tolypamide features a new type of enzyme that is able to prenylate a range of substrates and has poten.....»»
Mitochondrial enzyme found to block cell death pathway points to new cancer treatment strategy
Researchers have discovered a new role for the DHODH enzyme in blocking a form of cell death called ferroptosis. Preclinical findings suggest that targeting DHODH could restore cell death and inhibit tumor growth......»»
Researchers discover regulatory pathway that blocks immune response against cancer
Researchers show that TIM-3 inhibits the STING signaling pathway in dendritic cells, thereby blocking their ability to elicit an immune response......»»
Genetics: Biosynthesis pathway of a new DNA nucleobase elucidated
DNA is composed of nucleobases represented by the letters A, T, G and C. They form the basis of the genetic code and are present in all living beings. But in a bacteriophage, another base, represented by the letter Z, exists. This exception, the only.....»»
Winning gene combination takes all
Researchers have traced the remaining last steps of the biological pathway that gives oats resistance to the deadly crop disease take-all......»»
Dalian coherent light source reveals oxygen production from three-body photodissociation of water
The provenance of oxygen on Earth and other solar planetary bodies is a fundamental research issue. It is widely accepted that the prebiotic pathway of oxygen production in the Earth's primitive atmosphere was via vacuum ultraviolet (VUV) photodissoc.....»»
Scientists provide new insights into the citric acid cycle
Researchers led by Professors Ivan Berg (University of Münster) and Wolfgang Eisenreich (TUM) report new insights into the citric acid cycle: Certain bacteria can use this central metabolic pathway "backward," but to do so, they must have very high.....»»
Researchers streamline molecular assembly line to design, test drug compounds
Researchers from North Carolina State University have found a way to fine-tune the molecular assembly line that creates antibiotics via engineered biosynthesis. The work could allow scientists to improve existing antibiotics as well as design new dru.....»»
Lighting the way to folding next-level origami
Origami may sound more like art than science, but a complex folding pathway that proteins use to determine their shape has been harnessed by molecular biologists, enabling them to build some of the most complex synthetic protein nanostructures to dat.....»»
Microbial production of a natural red colorant carminic acid
A research group at KAIST has engineered a bacterium capable of producing a natural red colorant, carminic acid, which is widely used for food and cosmetics. The research team reported the complete biosynthesis of carminic acid from glucose in engine.....»»
Scientists identify molecular pathway that helps moving cells avoid aimless wandering
Working with fruit flies, scientists at Johns Hopkins Medicine say they have identified a new molecular pathway that helps steer moving cells in specific directions. The set of interconnected proteins and enzymes in the pathway act as steering and ru.....»»
"Animal-stress" signal improves plant drought resilience
A team of Australian and German researchers has discovered a novel pathway that plants can use to save water and improve their drought tolerance......»»
Microbial consumption of mineral nitrogen promotes HONO emissions in agricultural soils
A new study indicates that microbial nitrate reduction is an important nitrous acid (HONO) production pathway in aerobic soils. This suggests that the terrestrial ecosystems favoring it could be hotspots for HONO emissions, thereby influencing atmosp.....»»
New antibiotic clears multi-drug resistant gonorrhea in mice in single dose
A new antibiotic compound clears infection of multi-drug resistant gonorrhea in mice in a single oral dose, according to a new study. The compound targets a molecular pathway found in bacteria but not humans and could lead to new treatments for gonor.....»»
Marketplace literacy as a pathway to a better world: Evidence from field experiments
If you are a consumer and/or entrepreneur who can make decisions based on cost, competition, supply and demand, you probably possess an element of marketplace literacy......»»
New CRISPR screening technique leads to discovery of pathway that may be linked to cancer initiation
A new genome-wide CRISPR screening technique conducted by researchers at Vanderbilt University is offering new insights about how tumors in 80 to 90% of all cancers grow......»»
Two European companies are mapping a future service for direct air capture to sequestration of CO2
The Swiss-based, venture capital-backed, direct air capture technology developer Climeworks is partnering with a joint venture between the government of Norway and massive European energy companies to map the pathway for a business that could provide.....»»