Activating immune cells for cancer nano-immunotherapy
With nanotechnology we can understand, mimic, and modulate our immune system. For her Ph.D. research, Annelies Wauters studied how tiny nanocarriers can be used to control the immune system, and target and activate immune cells to fight cancer cells......»»
Dogma-challenging telomere findings may offer new insights for cancer treatments
A new study led by University of Pittsburgh and UPMC Hillman Cancer Center researchers shows that an enzyme called PARP1 is involved in repair of telomeres, the lengths of DNA that protect the tips of chromosomes, and that impairing this process can.....»»
Geologists, biologists unearth the atomic fingerprints of cancer
Scientists at the University of Colorado Boulder and Princeton University have, for the first time, employed a tool often used in geology to detect the atomic fingerprints of cancer......»»
Researchers develop a nanoparticle that can penetrate the blood-brain barrier
Researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine have developed a nanoparticle that can penetrate the blood-brain barrier. Their goal is to kill primary breast cancer tumors and brain metastase.....»»
Simulated chemistry: New AI platform designs tomorrow"s cancer drugs
Scientists at UC San Diego have developed a machine learning algorithm to simulate the time-consuming chemistry involved in the earliest phases of drug discovery, which could significantly streamline the process and open doors for never-before-seen t.....»»
Researchers develop new AI tool for fast and precise tissue analysis to support drug discovery and diagnostics
A team of scientists from A*STAR's Genome Institute of Singapore (GIS) and Bioinformatics Institute (BII) has developed a new AI software tool called "BANKSY" that automatically recognizes the cell types present in a tissue, such as muscle cells, ner.....»»
First steps toward a whole-body map of molecular responses to exercise
Research definitively confirms that muscle-moving, calorie-burning activity slows the advance of disease, improves cognitive function, boosts the immune system, and reduces rates of mortality from all causes......»»
New discovery of a mechanism that controls cell division
Researchers at Umeå University, Sweden, have discovered that how a special protein complex called the Mediator moves along genes in DNA may have an impact on how cells divide. The discovery may be important for future research into the treatment of.....»»
Researchers develop "founding document" on synthetic cell development
Cells are the fundamental units of life, forming the variety of all living things on Earth as individual cells and multicellular organisms. To better understand how cells perform the essential functions of life, scientists have begun developing synth.....»»
Nano-drugs hitching a ride on bacteria could help treat pancreatic cancer
Many pancreatic tumors are like malignant fortresses, surrounded by a dense matrix of collagen and other tissue that shields them from immune cells and immunotherapies that have been effective in treating other cancers. Employing bacteria to infiltra.....»»
Bioreactor processes and cryotechnologies improve active ingredient tests using human cell cultures
Many new drug candidates end up failing because they cause serious side effects in clinical trials even though lab tests involving cell cultures have been successful. This is a common occurrence if the cells used come from animal tissue, for example......»»
Understanding cellular transcription responses to oxygen deprivation
A multiprotein complex is essential for regulating cellular responses to oxygen deprivation, a key feature of cancer, according to a Northwestern Medicine study published in the Proceedings of the National Academy of Sciences......»»
Cell contraction drives the initial shaping of human embryos, study finds
Human embryo compaction, an essential step in the first days of an embryo's development, is driven by the contractility of its cells. This is the finding of a team of scientists from CNRS, Institut Curie, Inserm, AP-HP and the Collège de France. Pub.....»»
Study uncovers the secret of long-lived stem cells
Nothing lives forever, but compared to other cells in the body, hematopoietic stem cells (HSCs) are remarkably long-lived. HSCs are blood-forming cells—they give rise to rapidly dividing progenitor cells, which in turn generate hundreds of billions.....»»
Researchers suggest that mechanical pressure triggers a key event in HIV infection
It has been more than 40 years since the beginning of the HIV/AIDS epidemic and scientists still don't fully understand how HIV enters and replicates in human cells, which has hindered the development of treatments......»»
Plant science research paves the way for deeper understanding of how the plant immune system functions
Researchers in the laboratory of Tessa Burch-Smith, Ph.D. at the Danforth Plant Science Center and the University of Tennessee, Knoxville, are conducting pioneering work to discover how plants transmit information, important molecules, and viruses be.....»»
Study reveals cancer vulnerabilities in popular dog breeds
Medium-sized dogs have a higher risk of developing cancer than the very largest or smallest breeds, according to a UC Riverside study......»»
Scientists" research on RNA editing illuminates possible lifesaving treatments for genetic diseases
A team at Montana State University published research this month that shows how RNA, the close chemical cousin to DNA, can be edited using CRISPRs. The work reveals a new process in human cells that has potential for treating a wide variety of geneti.....»»
Cartilage healing discovery in animal models could lead to new human therapies
Researchers hope their discovery about the healing properties of fetal cartilage cells in mice will lay the groundwork for new treatments for human growth disorders and degenerative diseases......»»
Fruit fly helps unlock clues about how organs, tissue and cancer grow
The fruit fly, Drosophila, has been used by scientists for more than 100 years to unravel key features of life on Earth, such as how animals respond to the sun and how the bodies of animals are patterned from head to tail......»»
Study reveals protein"s key role in helping cilium transmit signals to the rest of the cell
The essential role played by a protein in the functioning of cells is revealed in new work from the laboratory of Université de Montréal medical professor Frédéric Charron, holder of the Canada Research Chair in Developmental Neurobiology......»»