Scientists report that buffer and pH strongly affect the phase separation of SARS-CoV-2 N protein
In a new paper published in Molecular Biology of the Cell, the Allain lab (IBC) reported that the phase separation of the SARS-CoV-2 N protein strongly depends on the chosen buffer and pH. For example, the protonation of a single histidine side chain.....»»
Researchers discover two vesicle fusion mechanisms while studying vesicle movement in living cells
Cells intake substances from the outside world by encapsulating them in vesicles called endosomes, which are subsequently transported throughout the cell. During the transport process, vesicles fuse with other intracellular organelles. However, obser.....»»
You Asked: HDMI 2.1 and Blu-ray, TV life spans, and 2023 TV price drops
How long should a QLED TV last? Will 2023 TV prices go down even further? And whatever happened to dual-cell TV tech?.....»»
Researchers envision sci-fi worlds involving changes to atmospheric water cycle
Human activity is changing the way water flows between the Earth and atmosphere in complex ways and with likely long-lasting consequences that are hard to picture......»»
Unleash the beast: High Performance Cycle’s electric mountain bike
A lot of distinct components and a hefty frame smooth out some nasty terrain. Enlarge (credit: John TImmer) I found myself in the air long enough to give some thought to how I could land while remaining atop the bicycle.....»»
How plants heal wounds: Mechanical forces guide direction of cell division
Plants are made up of very rigid cells. Much like bricks in a wall, this feature gives them the structural support to maintain their shape and to stand upright against gravity. However, just like any living organism, plants can be injured, for instan.....»»
Scientists propose AI framework for mass-manufacturing of stem cells for regenerative medicine
Some stem cells have a natural ability to divide into more cells and develop into various specialized blood, bone or muscle cells. These pluripotent stem cells offer great promise for new cell treatments and regenerative medicine, researchers say......»»
Apple restarts the developer beta cycle once again
Following the public release of its operating systems in early March, Apple has started the beta cycle from square one with new builds of iOS, iPadOS, tvOS, watchOS, and macOS Sonoma for developers to try out.iOS 17Developers participating in Apple's.....»»
EV battery cell production begins at GM"s Ultium plant in Tennessee
The first battery cells were shipped March 21 from the Ultium Cells plant in Spring Hill, Tenn......»»
Wound treatment hydrogel infused with amino acid kills bacteria naturally and promotes cell growth
Hydrogels are popular for use in skin ailments and tissue engineering. These polymer-based biocompatible materials are useful for their abilities to retain water, deliver drugs into wounds, and biodegrade. However, they are complicated to manufacture.....»»
New single-cell analysis tech incorporates advanced fiber optics directly into microfluidic chips
Droplet microfluidics has revolutionized single-cell analysis, crucial for genomics, drug discovery, and diagnostics, by partitioning samples into nanoliter droplets for detailed cellular analysis. Yet, its broader adoption is hindered by the complex.....»»
Scientists discover a key quality-control mechanism in DNA replication
When cells in the human body divide, they must first make accurate copies of their DNA. The DNA replication exercise is one of the most important processes in all living organisms and is fraught with risks of mutation, which can lead to cell death or.....»»
Researchers discover new microRNA-regulated pathway to boost iPS cell-derived platelet production
A team of researchers led by Professor Koji Eto (Department of Clinical Application) recently discovered the importance of a microRNA-based regulatory mechanism for enhancing the quality and quantity of platelets generated by iPS cell-derived megakar.....»»
In Canada"s Quebec, residents miffed over mining boom
Canada's Quebec province is rich with minerals needed for everything from electric cars to cell phones, but residents living atop the potential windfall are worried their backyards will be dug up—and they won't get a dime......»»
Memories of mitosis: Molecular mechanism that detects defects during cell division could aid cancer treatment
Every day, our cells are hard at work multiplying. Cell division is a precise process, but sometimes this process is impaired and diseases like cancer occur. Mitosis is one of the most important phases in the cell cycle. During this phase, a cell's D.....»»
Antifungal activity of a maleimide derivative: Disruption of cell membranes and interference with iron ion homoeostasis
A small molecule library consisting of 40 compounds, specifically N-substituted maleimide and its derivatives, were initially screened in a study published in the journal Mycology, which was led by Prof. Ying Li (Xuzhou Medical University), Prof. Zuo.....»»
How much difference can one degree of warming make?
A vicious cycle of warming temperatures and reduced snowpack in northern forests is more severe than climate models have shown and could lead to increased fire risk and permanent damage to ecosystems......»»
Biologists determine bacteria sense damage to relatives
Carnegie Mellon University biologists have discovered that Vibrio cholerae, the bacteria behind the cholera disease, can sense when its relatives die. Bacterial cell death is often accompanied by lysis, where the cell explodes, releasing internal cel.....»»
GPT-4 for identifying cell types in single cells matches and sometimes outperforms expert methods
GPT-4 can accurately interpret types of cells important for the analysis of single-cell RNA sequencing—a sequencing process fundamental to interpreting cell types—with high consistency to that of time-consuming manual annotation by human experts.....»»
DNA nanotube rings: Research team develops important building block for artificial cells
During cell division, a ring forms around the cell equator, which contracts to divide the cell into two daughter cells. Together with researchers from Heidelberg, Dresden, Tübingen and Harvard, Professor Jan Kierfeld and Lukas Weise from the Departm.....»»