Fighting viruses with interchangeable defense genes
Bacteria rapidly modify mobile parts of their genome to develop resistance to viruses......»»
Cell-free DNA identifies early signs of relapse in pediatric medulloblastoma
Findings show that cell-free DNA in cerebrospinal fluid can be used to detect measurable residual disease and identify patients at risk of relapse......»»
Lower airways are distinct in cystic fibrosis even at younger ages
In the largest study of its kind, researchers found that the lower airways in children with cystic fibrosis (CF) have a higher burden of infection, more inflammation and lower diversity of microorganisms, compared to children with other illnesses who.....»»
Modeling cellular migration
A new model sheds light on the function of a protein that is a major player in cancer growth, and their results could one day help researchers determine better ways to stop the spread of cancer......»»
It"s not all-right: Problems when your body doesn"t recognize your own left-handed RNA
By generating a specific mutation in lab mice, researchers determined that a protein domain in an enzyme called adenosine deaminase 1 p150 is necessary for binding and editing certain RNA molecules. Mutant mice showed inhibited growth after birth, as.....»»
New PCR assays offer hope in the fight against the environmental spread of antimicrobial resistance
Researchers have successfully trialed two new qPCR assays to help detect the presence of transmissible AMR using water and wastewater samples. The scientists present a DNA-based testing method that provides a surrogate for monitoring AMR, which will.....»»
Researchers target tumors with intracellular precision
A non-toxic, bacteria-based system can detect when it is inside a cancer cell and then release its payload of therapeutic drugs directly into the cell. The work could lead to effective, targeted therapies for currently untreatable cancers, such as li.....»»
How staphylococci protect themselves against antibiotics
The skin bacterium Staphylococcus aureus often develops antibiotic resistance. It can then cause infections that are difficult to treat. Researchers have now uncovered an ingenious way in which a certain strain of Staphylococcus aureus protects itsel.....»»
New, promising opportunities for treating skin fibrosis
Collagen, the main component of the skin's extracellular matrix, can cause a pathological condition if it is in excess. Applying an electric field to the skin affects collagen pathways, temporarily reducing collagen production and increasing its degr.....»»
TEDDY study compares characteristics of children diagnosed with type 1 diabetes before and after age 6
New findings add to a growing body of evidence indicating that type 1 diabetes is not a single disease. The presentation and, perhaps, cause of autoimmune diabetes differs among genetically high-risk children, the University of South Florida Health-l.....»»
Protein involved in heart development boosts stem cell strategy for heart repair, scientists show
With age, the human heart gradually loses its ability to repair itself following injury. Damage wrought by injuries such as cardiac ischemia and heart attack, which are associated with decreased oxygen levels in the heart, can cause the heart to func.....»»
Under arrest: Using nanofibers to stop brain tumor cells from spreading
Researchers have used high-density nanofibers that mimic the microenvironment of the brain to capture tumor cells, opening doors to novel therapeutic solutions for aggressive brain cancer......»»
Prozac pegged as potential treatment for leading cause of blindness
An antidepressant best known as Prozac could offer the first treatment for the leading cause of blindness among people over 50, new research suggests......»»
Skin-inspired sensors show how our body moves
Scientists have created wearable, stitchable, and sensitive sensors from flexible polymers and bundles of carbon fibre. Like our skin, these sensors respond to pressure and can measure body position and movement. They could be used to measure disease.....»»
Lab-grown ‘mini brains’ hint at potential treatment options for motor neurone disease and frontotemporal dementia
Researchers have developed 'mini brains' that allow them to study a fatal and untreatable neurological disorder causing paralysis and dementia -- and for the first time have been able to grow these for almost a year......»»
Fingerprinting proteins with force
What if we could identify proteins as easily as we can sequence DNA and RNA? Perhaps soon we will, thanks to new DNA Nanoswitch Calipers. DNA Calipers create a unique 'fingerprint' for peptides (the building blocks of proteins) by repeatedly applying.....»»
Targeted drug shows activity against brain metastases in kidney cancer
A targeted drug has shown promising activity against brain metastases resulting from kidney cancer, achieving a 50 percent response rate, and supporting further studies of the drug in this patient group whose poor prognosis has created a significant.....»»
Back pain common among astronauts offers treatment insights for the earth-bound
As more people travel into space, experts expect more physicians will see patients with space travel-related pain......»»
Research breakthrough could mean better treatment for patients with most deadly form of brain tumor
Scientists studying the most common and aggressive type of brain tumour in adults have discovered a new way of analysing diseased and healthy cells from the same patient......»»
Pilot study explores neural mechanisms of balance dysfunction after traumatic brain injury
Researchers examine graph-theoretical properties of brain networks in traumatic brain injury and controls and their association with balance impairment and structural damage......»»