A stealthy way to combat tumors
Researchers uncovered a new way to indirectly activate T cells that can target tumors, by recruiting a population of helper immune cells called dendritic cells......»»
Delta-like SARS-CoV-2 variants are most likely to increase pandemic severity
Mathematical model indicates SARS-CoV-2 variants that combine enhanced transmissibility with the ability to escape immunity cause more infections than variants with either trait alone. Understanding which type of variants are most likely to increase.....»»
New link between diet, intestinal stem cells and disease discovered
Obesity, diabetes and gastrointestinal cancer are frequently linked to an unhealthy diet. However, the molecular mechanisms responsible for this are not fully understood. Researchers have gained some new insights that help to better understand this c.....»»
Unborn babies could contract COVID-19, says study, but it would be uncommon
An unborn baby could become infected with COVID-19 if their gut is exposed to the SARS-CoV-2 virus, finds a new study......»»
Plant-derived antiviral is effective in blocking highly infectious SARS-CoV-2 Delta variant, say scientists
A plant-based antiviral has been found to be just as effective at treating all variants of the virus SARS-CoV-2, even the highly infectious Delta variant......»»
Repurposed ALS drug shows promise in mouse model of rare childhood genetic disorder
Riluzole, a drug approved to treat amyotrophic lateral sclerosis (ALS), a disease affecting nerve cells controlling movement, could slow the gradual loss of a particular brain cell that occurs in Niemann-Pick disease type C1 (NPC1), a rare genetic di.....»»
Breaking down cancer’s defenses
Researchers have developed a new probiotic bacteria designed to break down solid cancer cell walls and make other therapies more effective......»»
Urbanization not always bad for food and land use diversity
Widely accepted myths that urbanization negatively impacts food and land use biodiversity are incorrect, according to a team of researchers who developed a framework for evaluating this intersection......»»
Phages kill dystentery-causing bacteria and reduce virulence in surviving bacteria
Phages are viruses that infect bacteria and can also be used to treat human infections. However, as with antibiotics, bacteria can readily evolve resistance to phage attack, highlighting a key limitation to the use of phages as therapeutics. Now, res.....»»
Suffering from psoriasis? Blame this trio of proteins
About 7.5 million Americans suffer from psoriasis, an autoimmune disease that shows up as patches of red, inflamed skin and painful, scaly rashes. Although there are effective treatments for psoriasis, not everyone responds to these therapies -- and.....»»
Cystic fibrosis faithfully modeled in a human Lung Airway Chip
Despite advances in patient screenings and breakthrough therapies that allow CF patients now to live into their mid- to late 30s or 40s, sometimes even longer, all patients are plagued by bacteria settling in their mucus, which causes inflammation in.....»»
Human Proteoform Project to map proteins in human body
Now that the Human Genome Project has officially wrapped, an international team of researchers will map the entire collection of proteins in the human body. The large undertaking will characterize known proteoforms (specific protein molecules) as wel.....»»
Master developmental genes play role in adulthood
Among their many extraordinary feats, some planarian flatworms reproduce by tearing off pieces of themselves to regenerate new worms. Now, researchers have discovered that this process is controlled by Hox genes, a family of genes known to orchestrat.....»»
Nascent polypeptides stabilize ribosomes for uninterrupted translation
Protein production (translation) is a complex process involving machinery called ribosomes. How do cells counter ribosomal destabilization leading to premature termination of translation? Scientists have uncovered a novel role of nascent protein chai.....»»
Researchers discover new insights about tau proteins in people living with ALS
Investigators found elevated levels of tau and a phosphorylated form of the tau protein in brain tissue from deceased people who had amyotrophic lateral sclerosis (ALS) and carried a mutation in the C9orf72 gene. The team also identified new genetic.....»»
Researchers train computers to predict the next designer drugs
Researchers have trained computers to predict the next designer drugs before they are even on the market, technology that could save lives. Identifying these so-called 'legal highs' within seized pills or powders can take months, during which time th.....»»
Common blood pressure drug does not slow down the progression of more advanced Alzheimer’s, study finds
New research has shown the drug losartan, normally used to treat high blood pressure (hypertension), is not effective in slowing down the progression of Alzheimer's disease (AD) in people with mild-to-moderate disease after 12 months of treatment. Ho.....»»
Researchers tarmouse’s own cells, rather than using antibiotics, to treat pneumonia
Researchers have discovered a therapy that targets host cells rather than bacterial cells in treating bacterial pneumonia in rodents. The method involves white blood cells of the immune system called macrophages that eat bacteria, and a group of comp.....»»
Keeping chocolate milk smooth, stable without carrageenan
Fat-free chocolate milk processed for the first time with high-pressure jet technology exhibits enhanced viscosity, stabilizing cocoa particles in the fluid and eliminating the need for adding a controversial emulsifier. That's the conclusion of a te.....»»
COVID patients on SSRI antidepressants are less likely to die, study finds
A large analysis of health records from 87 health care centers across the United States found that people taking a class of antidepressants called selective serotonin reuptake inhibitors (SSRIs), particularly fluoxetine, were significantly less likel.....»»