Blood vessels are guides for stimulating implants
A wireless neurostimulator a little bigger than a grain of rice can be put in place alongside blood vessels to treat neurological diseases and chronic pain......»»
Structure of a bacterial "drug pump" reveals new way to counter hospital-borne infection
By revealing the structure of a protein used by bacteria to pump out antibiotics, a research team designed an early-stage therapeutic that sabotages the pump and restores the effectiveness of antibiotics......»»
Researchers identify new targets for immunotherapy in colon cancer
Scientists identify a pathway of immune cell inhibition that may provide the basis for novel approaches to immunotherapy of colon cancer. Their results also highlight important roles of the intestinal microbiota in the development of the disease......»»
Men with high blood pressure have a biased recognition of other people’s anger
Men with high blood pressure have a biased recognition of other people's anger, as shown in a new study......»»
Apples and other fruits can host drug-resistant, pathogenic yeasts on surfaces, study finds
Fungicides used to prolong shelf life of fruits may select for pathogenic yeasts and boost transmission. Those pathogens include Candida auris, a drug-resistant pathogenic yeast found in stored apples in a recent study......»»
Convalescent plasma can be effective early COVID-19 therapy, study finds
Research shows that high-titer (antibody-rich) COVID convalescent plasma -- when administered to COVID-19 outpatients within nine days after testing positive -- reduced the need for hospitalization for more than half of a study's predominantly unvacc.....»»
Surprising way to make walking easier
New findings describe a novel way to reduce the energy people spend to walk, as much as by half, which could have applications for therapy received by patients with impaired walking abilities......»»
Global disparities persist in opioid painkiller access
Global opioid sales increased by an estimated 4% annually from 2015 to 2019, but massive disparities in access to essential pain relief medications persist between countries, a new study finds......»»
Classification of 16 adult sleep patterns based on large-scale sleep analysis
A research group found that the human sleep patterns could be classified into 16 types by combining ACCEL, their original machine learning algorithm for sleep-wake classification, the dimension reduction method and the clustering method. The accelera.....»»
Heart complications after a stroke increase the risk of future cardiovascular events
A large, observational study found that heart complications within one month after an ischemic stroke (blocked blood flow to the brain) are very common. This 'stroke-heart syndrome' may put stroke survivors at higher risk for death, heart attack or a.....»»
A scaffold with a twist: Cryo-EM reveals the building blocks of poxvirus
Researchers have revealed how poxviruses build their scaffold - a temporary protein coat that forms and disappears as the virus matures......»»
Design of protein binders from target structure alone
Scientists have now created a powerful new method for generating protein drugs. Using computers, they designed molecules that can target important proteins in the body, such as the insulin receptor, as well as vulnerable proteins on the surface of vi.....»»
"Off label" use of imaging databases could lead to bias in AI algorithms
Significant advances in artificial intelligence (AI) over the past decade have relied upon extensive training of algorithms using massive, open-source databases. But when such datasets are used 'off label' and applied in unintended ways, the results.....»»
AI provides accurate breast density classification
An artificial intelligence (AI) tool can accurately and consistently classify breast density on mammograms, according to a new study......»»
Labeling key to success of software company innovations
Companies in the software industry, where novel ideas are prized, use linguistic tactics to develop new labels for their innovations to stay ahead of competitors......»»
Simulated human eye movement aims to train metaverse platforms
Computer engineers have developed virtual eyes that simulate how humans look at the world accurately enough for companies to train virtual reality and augmented reality programs. Called EyeSyn for short, the program will help developers create applic.....»»
BioCro software for growing virtual crops improved
A team has revamped the popular crop growth simulation software BioCro, making it a more user-friendly and efficient way to predict crop yield. The updated version, BioCro II, allows modelers to use the technology much more easily and includes faster.....»»
Rebooting evolution
The building blocks of life-saving therapeutics could be developed in days instead of years thanks to new software that simulates evolution. Proseeker is the name of a new computational tool that mimics the processes of natural selection, producing p.....»»
CROPSR: A new tool to accelerate genetic discoveries
Scientists have developed CROPSR, the first open-source software tool for genome-wide design and evaluation of guide RNA (gRNA) sequences for CRISPR/Cas9 experiments. This tool significantly shortens the time required to design a CRISPR experiment an.....»»
DNA design brings predictability to polymer gels
Simulations have led to the fabrication of a polymer-DNA gel that could be used in tissue regeneration and robotics......»»