Stiffness and viscosity of cells found to differ in cancer and other diseases
During illness, the stiffness or viscosity of cells can change. Tom Evers demonstrated this by measuring such properties of human immune cells for the first time. "The stiffness of certain cells could be a way to make a diagnosis," Evers said......»»
Not wrapping but folding: Bacteria also organize their DNA, but they do it a bit differently
Some bacteria, it turns out, have proteins much like ours that organize the DNA in their cells. They just do it a bit differently. This is revealed by new research from biochemists at the Leiden Institute of Chemistry and the Max Planck Institute for.....»»
Nanowires create elite warriors to enhance T cell therapy
Adoptive T-cell therapy has revolutionized medicine. A patient's T-cells—a type of white blood cell that is part of the body's immune system—are extracted and modified in a lab and then infused back into the body, to seek and destroy infection, o.....»»
Swimming microrobots deliver cancer-fighting drugs to metastatic lung tumors in mice
Engineers at the University of California San Diego have developed microscopic robots, known as microrobots, capable of swimming through the lungs to deliver cancer-fighting medication directly to metastatic tumors. This approach has shown promise in.....»»
"Synthetic" cell shown to follow chemical directions and change shape, a vital biological function
In a feat aimed at understanding how cells move and creating new ways to shuttle drugs through the body, scientists at Johns Hopkins Medicine say they have built a minimal synthetic cell that follows an external chemical cue and demonstrates a govern.....»»
Scientists propose novel AI approach for lipid nanoparticles screening in mRNA delivery
The targeted treatment of pan-cancer by messenger RNA (mRNA) vaccine is a hot topic in drug research. A key challenge in mRNA design is the construction of delivery systems called lipid nanoparticles (LNPs), which serve as carriers to deliver mRNA th.....»»
AI system learns to speak the language of cancer to enable improved diagnosis
A computer system which harnesses the power of AI to learn the language of cancer is capable of spotting the signs of the disease in biological samples with remarkable accuracy, its developers say......»»
UAW, Ultium Cells reach tentative agreement
The UAW and Ultium Cells have come to a tentative agreement on improvements in wages, health and safety measures after 18 months of negotiation. The agreement serves as a local supplement to the bigger master contract of the Detroit 3......»»
Lung organoids reveal how pathogens infect human lung tissue
How do pathogens invade the lungs? Using human lung microtissues, a team at the Biozentrum of the University of Basel has uncovered the strategy used by a dangerous pathogen. The bacterium targets specific lung cells and has developed a sophisticated.....»»
Spliceosomes: New technique tracks proteins involved in RNA splicing
Bodybuilders and cellular mechanisms agree generating protein is a heavy lift. To complete the task, cells rely on complexes called spliceosomes. These molecular machines snip extra bits out of our genes' RNA copies and piece together precise instruc.....»»
Improved prime editing system makes gene-sized edits in human cells at therapeutic levels
Scientists at the Broad Institute of MIT and Harvard have improved a gene-editing technology that is now capable of inserting or substituting entire genes in the genome in human cells efficiently enough to be potentially useful for therapeutic applic.....»»
Dead Cells designer’s new game, Tenjutsu, is a yakuza action roguelike
Devolver Digital will publish Tenjutsu, the next game from Dead Cells creator Sébastien Benard......»»
Unlocking banana disease resistance: Key enzymes identified for phytoalexin synthesis
Bananas are a vital crop globally, but their yields are threatened by various diseases, particularly banana fusarium wilt caused by Fusarium oxysporum. Traditional control methods, including chemical pesticides, pose environmental risks and are not a.....»»
A novel spray device helps researchers capture fast-moving cell processes
Cells are the basic units of life—but many of their fundamental processes happen so fast and at such small length scales that current scientific tools and methods can't keep up, preventing us from developing a deeper understanding......»»
Enzyme research reveals why some cancer drugs cause severe side effects
Some cancer drugs cause severe side effects because they are not working accurately enough. A team at the University of Würzburg led by biochemist Caroline Kisker has now discovered why......»»
How a protein component of nuclear pore complexes regulates development of blood cells, contributes to myeloid disorders
Nuclear pore complexes (NPCs) are channels composed of multiple proteins that ferry molecules in and out of the nucleus, regulating many critical cellular functions, such as gene expression, chromatin organization and RNA processes that influence cel.....»»
Molecules derived from sea sponge show promising effects in cancer, mitochondrial function
A groundbreaking study led by the USC Leonard Davis School of Gerontology in collaboration with Dominican University of California explores how small molecules derived from sea sponges affect energy production in mitochondria and details their remark.....»»
Study links nanoparticles to altered blood vessel formation in embryos
Human life begins with a single egg cell that grows into a human being with trillions of cells. To ensure that the highly complex development of tissues and organs is as protected as possible, the placental barrier keeps pathogens and foreign substan.....»»
Q&A: Studies reveal gut"s true stem cells, challenging previous assumptions
Two independent studies by Columbia scientists suggest that research into the gut's stem cells over the past 15 years has been marred by a case of mistaken identity: Scientists have been studying the wrong cell......»»
Ancient Egyptian skull shows evidence of cancer, surgical treatment
“An extraordinary new perspective in our understanding of the history of medicine.” Enlarge (credit: Tondini, Isidro, Camarós, 2024.) The 4,000-year-old skull and mandible of an Egyptian man show signs of cancerous.....»»
Key mechanism for maintaining proper telomere length identified
The length of telomeres that protect the ends of our chromosomes should be tightly regulated. Those that are too long predispose to cancer, and those that are too short lose their protective ability, resulting in telomere disorders with serious healt.....»»