Microreactor for synthesis with Grignard reagents
In 1912, Victor Grignard was awarded the Nobel Prize in Chemistry for his discovery of what came to be known as Grignard reagents. Since then, these compounds have come to play a key role in the chemical and pharmaceutical industries. Now, in a devel.....»»
Scientists discover new structures for unique hybrid materials by altering their chemical bonds
Putting a suite of new materials synthesis and characterization methods to the test, a team of scientists from the University of Iowa and the U.S. Department of Energy's (DOE) Brookhaven National Laboratory has developed 14 organic-inorganic hybrid m.....»»
Simultaneous synthesis and fixing of covalent organic frameworks
Covalent organic frameworks (COFs) are versatile materials composed of interconnected organic molecules held together by covalent bonds. These frameworks can be constructed in two-dimensional or three-dimensional (3D) forms which possess a unique com.....»»
Aggregation-induced catalysis: Asymmetric catalysis with chiral aggregates
Asymmetric synthesis and catalysis have been actively pursued in chemical and materials sciences for some time. Increasing numbers of drugs and pesticides contain chiral structural units in their structures since drug actions require conformational m.....»»
Scientists presents a one-step laser synthesis method for fabricating wideband microwave absorption metamaterial
Scientists from Chinese Academy of Sciences Ningbo Institute of Materials Technology and Engineering, National Physical Laboratory (U.K.), The University of Manchester (U.K.) and National University of Singapore have developed a new approach, publish.....»»
Click chemistry as a connection tool: Grand opportunities and challenges
Click chemistry could help to synthesize a variety of molecules quickly and reliably by piecing together small units. In particular, it emphasizes the development of new combinatorial chemistry methods based on the synthesis of carbon-heteroatomic bo.....»»
Study presents new database linking RNA editing and blood cell differentiation
The process of converting DNA to proteins through an RNA is far from straightforward. Of the several types of RNA involved in the process of protein synthesis, a few may be edited mid-way. In mammals, RNA editing mostly involves converting adenosine.....»»
DNA-repair protein complex is a shapeshifter, reconfiguring itself to meet the demands of each task
Transcription factor IIH, or TFIIH, pronounced "TF two H," is a veritable workhorse among the protein complexes that control human cell activity. It plays critical roles both in transcription—the highly regulated enzymatic synthesis of RNA from a D.....»»
SuFEx as a new generation of click chemistry: Synthesis and development of linkers
Organosulfur(VI) fluoride compounds display excellent chemical stability, and yet can efficiently realize diverse linkages via the activation of specific conditions. Based on its unique nature, Sharpless, Dong and coworkers introduced SuFEx as a new.....»»
Sustainability: New catalyst makes chemical processes more efficient and less harmful to the environment
A new discovery by the Politecnico di Milano opens up new perspectives in the field of sustainable chemical synthesis, promoting innovative solutions that allow chemicals to be created in a more efficient and environmentally friendly way. The researc.....»»
Study offers strategy for green synthesis of 15N-amino acids
15N isotope-labeled amino acids (15N-amino acids) provide a safe and effective tracer tool for studying the synthesis of natural products, protein metabolism, and disease diagnosis and treatment in living organisms. In addition, it is an important sy.....»»
A divergent strategy enables molecular diversity: Synthesis of nine complex natural compounds
A research group led by chemist Thomas Magauer has accomplished a divergent strategy to synthesize nine complex natural compounds. The developed method requires significantly less time and results in a variety of compounds with different structures a.....»»
Towards synthesis of phenanthridine-based pharmaceutical compounds
Phenanthridines are heterocyclic compounds consisting of two six-membered benzene rings fused to a six-membered ring containing nitrogen. They are found in many naturally occurring organic compounds known for their anticancer and antitumor properties.....»»
Protective molecules facilitate molybdate anion binding to create novel silver nanoclusters
Silver nanocluster synthesis, or the binding of a silver atom to negatively charged anions, is often plagued by stability, sizing uniformity and surface composition issues. Protective molecules that bind the surface of silver nanoclusters, called lig.....»»
Discovery of a new mechanism that may promote healthy aging of our cells
All biological processes in our cells are constantly monitored to prevent the accumulation of defective proteins. In the worst case, such protein clumps can trigger diseases. The synthesis of new proteins is particularly susceptible to errors. Errono.....»»
Neanderthal adhesives were made through a complex synthesis process
Birch bark was heated in underground chambers to create a tougher adhesive. Enlarge (credit: Halamka / GETTY IMAGES) As Homo sapiens, we often consider ourselves to be the most intelligent hominins. But that doesn’t me.....»»
Researchers invent low-temperature synthesis method for high-quality tellurium nanomesh for next-generation electronics
A collaborative team led by researchers from City University of Hong Kong (CityU) recently invented an innovative method for synthesizing high-quality, semiconducting nanomesh at a lower temperature and production cost than conventional methods. The.....»»
Light and nickel found to simplify cross-coupling reactions
Cross-coupling reactions—chemical transformations in which two fragments are joined together—are a valuable tool in the synthesis of organic molecules. Applications range from drug development and synthesis of naturally occurring molecules to mat.....»»
Researchers report light-controlled transport of biomolecules across the cell membrane
Crossing the membrane is a major challenge on the journey through the cell. Large biomolecules usually benefit from different transport strategies to overcome the lipid bilayer, so the design and synthesis of new carriers is key for the delivery of h.....»»
Paul McCartney: “Final” Beatles song out this year, thanks to AI
Machine learning tech pioneered for "Get Back" will bring Lennon song to life. Here's how. Enlarge / A portrait of The Beatles in 1966, as imagined by AI image synthesis. (credit: Stable Diffusion) On Tuesday, BBC Radio.....»»
Paul McCartney: AI has enabled a “final” Beatles song
AI voice-separation tech pioneered for "Get Back" will bring Lennon demo to life. Enlarge / A portrait of The Beatles in 1966, as imagined by AI image synthesis. (credit: Stable Diffusion) On Tuesday, BBC Radio 4's Today.....»»