Glycerol phosphate serves as a terminator of glycan elongation in cancer malignancy
Dystroglycans on epithelial cell surfaces interact with the extracellular matrix via long sugar chains (called matriglycans), and they are responsible for cell adhesion. Abnormalities in the formation of matriglycans can impair cell adhesion and caus.....»»
Machine learning helps predict drugs" favorite subcellular haunts
Most drugs are small molecules that bind firmly to a specific target—some molecule in human cells that is involved in a disease—in order to work. For example, a cancer drug's target might be a molecule that is abundant inside of cancer cells. The.....»»
Bing Chat’s ads are sending users to dangerous malware sites
The Bing Chat AI chatbot often serves up adverts to its users, but it turns out these ads can be hijacked by malicious websites containing dangerous malware......»»
Unraveling metabolic processes spanning from subcellular organelles to complex tissues
Metabolism serves as a direct reflection of biological functions and pathological conditions. Throughout the years, biologists and doctors have been delving into the intricate metabolic mechanisms underlying physiological processes and disease states.....»»
A new chemical tool for probing toxic formaldehyde"s dual nature
Compounds developed by University of Leicester Chemists aim to reveal the dual nature of formaldehyde, a chemical that is known to cause cancer but is also believed to play important roles in our biology......»»
Scientists reveal how phosphate escapes from actin filaments
Actin filaments are dynamic protein-fibers in the cell built from single actin proteins. Many cellular functions, including cell movement, are regulated by constant filament assembly and disassembly. The disassembly phase is initiated by the release.....»»
How CEO lies can boost stock ratings and fool even respected financial analysts
The multibillion-dollar collapse of FTX—the high-profile cryptocurrency exchange whose founder now awaits trial on fraud charges—serves as a stark reminder of the perils of deception in the financial world......»»
3D organoids unlock promising insights into lung cancer in dogs
Veterinary researchers have used organoids—three-dimensional organ-like structures grown from stem cells and tissue samples—to investigate the biological processes of lung cancer in dogs, a disease that is much rarer in our canine friends than it.....»»
Chromosomal instability in cancer cells causes DNA damage and promotes invasiveness: Study
Chromosomal instability is a phenomenon characterized by rapid changes in the number and structure of chromosomes during cell division. It is very common in solid tumors and it is linked to the aggressive spread of cancer, that is to say, metastasis......»»
Ford pauses work on $3.5 billion battery factory in Michigan
The site was going to make lithium iron phosphate cells for electric vehicles. Enlarge / Ted Miller, manager of Ford Battery Cell Research and Advanced Engineering, holds a lithium iron phosphate (LFP) battery during a presentati.....»»
Researchers challenge long-standing theory guiding nanoparticle treatment of tumors
Researchers at the University of Toronto have developed a new theory to explain how nanoparticles enter and exit the tumors they are meant to treat, potentially rewriting an understanding of cancer nanomedicine that has guided research for nearly fou.....»»
Research team develops new way to target cancer cells
Researchers from the University of Arizona Cancer Center have identified a new method of activating specific molecules to target cancer cells while leaving healthy cells unharmed......»»
From forming embryo to cancer metastasis: The significance of collective cell movement
Against all expectations, the most common tissue in our bodies behaves differently at different length scales. That's what physicist Luca Giomi discovered in his research into the flow of cells. "Our findings are even more interesting than we hoped f.....»»
Disrupting a core metabolic process in T cells may improve their therapeutic efficacy
In exploring an aspect of how killer T cells generate the raw materials required for their proliferation, a Ludwig Cancer Research study has uncovered an unexpected link between the immune cells' metabolism, regulation of gene expression, persistence.....»»
How bats evolved to avoid cancer
A new paper titled "Long-read sequencing reveals rapid evolution of immunity and cancer-related genes in bats" in Genome Biology and Evolution shows that rapid evolution in bats may account for the animals' extraordinary ability to both host and surv.....»»
Drug delivery platform leverages air-filled protein nanostructures and uses sound for targeting
Chemotherapy as a treatment for cancer is one of the major medical success stories of the 20th century, but it's far from perfect. Anyone who has been through chemotherapy or who has had a friend or loved one go through it will be familiar with its m.....»»
Mature sperm lack intact mitochondrial DNA, study finds
New research provides insight about the bedrock scientific principle that mitochondrial DNA—the distinct genetic code embedded in the organelle that serves as the powerplant of every cell in the body—is exclusively passed down by the mother......»»
Saturday Citations: Wear a helmet around supermassive black holes. Also, cute koalas and quantum therapy for cancer
This week, we looked at the swirling chaos around supermassive black holes, anthropogenic climate effects over the Atlantic ocean and the threats to koalas......»»
Saturday Citations: Wear a helmet around supermassive black holes. Also, cute koala bears and quantum therapy for cancer
This week, we looked at the swirling chaos around supermassive black holes, anthropogenic climate effects over the Atlantic ocean and the threats to koala bears......»»
New nanotech weapon takes aim at hard-to-treat breast cancer
Breast cancer in its various forms affects more than 250,000 Americans a year. One particularly aggressive and hard-to-treat type is triple-negative breast cancer (TNBC), which lacks specific receptors targeted by existing treatments. The rapid growt.....»»
New research signals a quantum leap for brain tumor treatment
Researchers have discovered a new way to target and kill cancer cells in hard-to-treat brain tumors using electrically charged molecules to trigger self-destruction, which could be developed into a spray treatment used during surgery......»»