Unveiling the mysteries of cell division in embryos with timelapse photography
The beginning of life is shrouded in mystery. While the intricate dynamics of mitosis are well-studied in the so-called somatic cells—the cells that have a specialized function, like skin and muscle cells—they remain elusive in the first cells of.....»»
CRISPR-based system labels extracellular vesicles with "barcodes" to better understand cell-to-cell communication
Cell-to-cell communication through nanosized particles, working as messengers and carriers, can now be analyzed in a whole new way, thanks to a new method involving CRISPR gene-editing technology......»»
By exerting "crowd control" over mouse cells, scientists make progress towards engineering tissues
Genes aren't the sole driver instructing cells to build multicellular structures, tissues, and organs. In a paper published in Nature Communications, USC Stem Cell scientist Leonardo Morsut and Caltech computational biologist Matt Thomson characteriz.....»»
Researchers characterize regulating mechanism of orderly zygotic genome activation in early embryos
Early development of an embryo is solely supported by maternally deposited RNAs and proteins until its own genome is activated through a process called zygotic genome activation (ZGA). Recent work by Chinese scientists has revealed a novel molecular.....»»
A single cell"s siesta: How non-moving single-celled organisms manage to avoid bright light
Too much of a good thing is no good at all. Living organisms enjoy sunlight—in fact, they need it to stay alive—but they tend to avoid light that is too bright. Animals go to their shelter, humans have a siesta, even plants have mechanisms to avo.....»»
Viscosity of materials key to cell differentiation: New insights could improve design of biomaterials
An IBEC-led study has revealed how mesenchymal stem cells respond to the viscosity of their environment, a key aspect in their differentiation process......»»
How marine worms regenerate lost body parts: Return of cells to stem cell-like state could be key
Many living organisms are able to regenerate damaged or lost tissue, but why some are particularly good at this and others are not is not fully understood. Molecular biologists Alexander Stockinger, Leonie Adelmann and Florian Raible from the Max Per.....»»
Selenoproteins open new strategies for treating certain cancers in children
Selenoproteins are crucial for several biological functions, including the breakdown of harmful substances, immune system support, and regulating metabolic processes. However, in specific contexts, these proteins can be misused and shield cancer cell.....»»
Study uncovers role of tissue viscoelasticity in cell response
To the casual eye, a memory foam mattress would appear to have no relationship to the behavior of cells and tissues. But an innovative study carried out at the Centro de Investigaciones Cardiovasculares (CNIC) in Madrid shows that viscoelasticity—t.....»»
The First Crispr Treatment Is Making Its Way to Patients
It’s been a year since the gene-editing treatment Casgevy was approved for sickle cell disease and a related blood disorder. It’s finally being infused into patients......»»
Telescope for NASA"s Roman mission complete, delivered to Goddard
NASA's Nancy Grace Roman Space Telescope is one giant step closer to unlocking the mysteries of the universe. The mission has now received its final major delivery: the Optical Telescope Assembly, which includes a 7.9-foot (2.4-meter) primary mirror,.....»»
Picky proteins: Understanding yeast adaptor protein selectivity
The cellular membrane controls the passage of substances in and out of the cell. Some larger cargo, such as membrane proteins, nutrients, and pathogens, enter the cell via a process known as clathrin-mediated endocytosis......»»
A new mission to Pluto could answer the questions raised by New Horizons
Pluto may have been downgraded from full-planet status, but that doesn't mean it doesn't hold a special place in scientist's hearts. There are practical and sentimental reasons for that—Pluto has tantalizing mysteries to unlock that New Horizons, t.....»»
Squishy microgels in granular biomaterials confine and direct cell behavior
A simple biomaterial-based strategy that can influence the behavior of cells could pave the way for more effective medical treatments such as wound healing, cancer therapy and even organ regeneration, according to a research team at Penn State......»»
Deals: M4 MacBook Pro hits all-time low at $125 off, GPS+Cell Apple Watch Series 10 $50 off, Alpine Loops, more
Joining all-time lows on the 42mm and 46mm Apple Watch Series 10 starting from $349, today Amazon has decided to carry the deep discounts over to the GPS+Cell models, including both the aluminum and higher-end titanium variants starting at $449 (the.....»»
Using CRISPR to decipher whether gene variants lead to cancer
In recent years, scientists have created a range of new methods based on CRISPR-Cas technology for precisely editing the genetic material of living organisms. One application is in cell therapy: A patient's immune cells can be specifically reprogramm.....»»
Unveiling the secrets of aging: Scientists discover dual role of immunoglobulins
A team of scientists from the Chinese Academy of Sciences (CAS) and BGI Research has uncovered the intricate mechanisms by which immunoglobulins influence the aging process, a finding that might reshape our understanding of aging......»»
Mitochondrial study offers new insights into how our cells process RNA for energy production
Researchers at the Department of Cell and Molecular Biology, Karolinska Institutet have made a major discovery in how human cells produce energy. Their study, published in The EMBO Journal, reveals the detailed mechanisms of how mitochondria process.....»»
MultiVersus is underperforming, but Warner Bros. is still focused on IP
Warner Bros. Discovery is tripling down on its IP for its gaming division despite MultiVersus underperforming to the tune of $100 million......»»
Researchers uncover focal adhesions as subcellular signaling hubs in PI3K-AKT pathway
The phosphatidylinositol 3-kinase (PI3K)-AKT signaling pathway is one of the most critical and extensively investigated signaling pathways. It is the central regulator of various cellular processes including cell growth, proliferation, metabolism, an.....»»
Beta cells: New insights into the structure, interactions and neuronal networking of primary cilia
Dysfunctions of the tiny cell processes (primary cilia) of the pancreatic beta cells could be a cause of type 2 diabetes. Little is known about the structure and function of these cilia. An international research team led by DZD researchers from the.....»»