New DNA sequencing technique preserves cells" locations within tissues
Within complex tissues such as cancer tumors, individual cells can vary widely from each other. Internally, cancer cells can develop unique DNA mutations and genomic changes, potentially leading to drug resistance, metastasis, or relapse. Externally,.....»»
Silencing in action: How cells "repress" genomic remnants of ancient viruses
Researchers have identified key cellular control sites that regulate gene expression and prevent the activation of "cryptic" genomic regions, including ancient viral sequences......»»
DNA origami and fluorescent probes can precisely release molecular cargo
In the world of nanotechnology, the development of dynamic systems that respond to molecular signals is becoming increasingly important. The DNA origami technique, whereby DNA is programmed so as to produce functional nanostructures, plays a key role.....»»
Scientists Will Engineer the Ocean to Absorb More Carbon Dioxide
A research consortium plans to revive geoengineering trials of the controversial iron fertilization technique to pull carbon dioxide from the air, despite public backlash.....»»
What Is Sickle Cell Disease?
You have around 35 trillion red blood cells moving around your body at all times. Typically they are rounded and flexible. What happens when they aren’t?.....»»
A 30-year-old man built muscle and burned fat in 4 months with a time-saving workout technique
A 30-year-old man built muscle and burned fat in 4 months with a time-saving workout technique.....»»
Computational tool can pinpoint causal relationships from complex biological data
Researchers have developed a tool that provides new insights into cause-and-effect relationships between cells and how these change over time......»»
Do bacteria age?
Any organism that lives, grows and reproduces must also age. People often think of aging in the physical sense—gray hair, slowed movements and wrinkles—but aging fundamentally occurs on a molecular level, inside of cells......»»
Scientists decipher the energy patterns in our cells
Our cells harness energy for essential functions such as division, wound healing, and our immune response to diseases including cancer. But until now, the mechanics of how that energy affects cell behavior—and how this relates to health outcomes—.....»»
Study sheds light on trade-off between noise and power in nanoscale heat engines
Thanks to nanoscale devices as small as human cells, researchers can create groundbreaking material properties, leading to smaller, faster, and more energy-efficient electronics. However, to fully unlock the potential of nanotechnology, addressing no.....»»
Optogenetic control reveals collective cell behavior
New research led by the Institute for Bioengineering of Catalonia (IBEC) has studied the migratory movement of groups of cells using light control. The results show that there is no leader cell that directs the collective movement, as previously thou.....»»
Researchers develop new method for delivering RNA and drugs into cells
Researchers at the University of Toronto and its hospital partners have developed a method for co-delivering therapeutic RNA and potent drugs directly into cells, potentially leading to a more effective treatment of diseases......»»
Trimetallic-based nanocarriers method shows promise for visualized idiopathic pulmonary fibrosis therapy
A research group from Ningbo Institute of Materials Technology and Engineering (NIMTE) of the Chinese Academy of Sciences (CAS) developed a novel method for idiopathic pulmonary fibrosis (IPF) therapy by transplanting mesenchymal stem cells (MSCs), w.....»»
Modified nano-sized cell particles found to boost cancer immunotherapy, reduce side effects
Immunotherapy is a type of cancer treatment that uses the body's own immune system to help fight cancer. This is by stimulating the immune response to recognize and attack cancer cells more effectively. The treatment involves using substances that bo.....»»
Technique to study how proteins bind to DNA is easily misused: Researchers offer a solution
Researchers at University of California San Diego have published new guidelines that could help scientists significantly improve their results when quantifying the interactions between DNA and proteins. Understanding these interactions is critical to.....»»
Ethics of biobanking for conservation: Researchers adjust ethical assessment tool for the use of genome research banks
In the face of the global biodiversity crisis, more and more biobanks are being set up to safeguard and potentially restore genetic diversity. Preserved tissue or cells allow scientists and conservationists to overcome spatial and even temporal fragm.....»»
Custom microfluidic chip design reshapes framework of spatial transcriptomics technology
Spatial transcriptomics has emerged as a powerful tool for in situ analysis of gene expression within tissues. However, current technologies still face several challenges, including high costs, limited field of view, and low throughput, significantly.....»»
How bacteria actively use passive physics to make biofilms
When we think about bacteria, we may imagine single cells swimming in solution. However, similarly to humans, bacterial cells often socialize, using surfaces to coalesce into complex heterogeneous communities called biofilms. Within a group, bacteria.....»»
Scientists develop super golden lettuce that"s richer in vitamin A
A research group has developed an innovative method for the biofortification of leaves and other green plant tissues, increasing their content of healthy substances such as beta-carotene, the main precursor of vitamin A in the human diet......»»
New technique boosts mutation rates in fruit flies for genetics research
A new technique, TF-High-Evolutionary (TF-HighEvo), allows large-scale assessment of de-novo mutations in multicellular organisms. Developed in collaboration with researchers from the European Molecular Biology Laboratory (EMBL) and the Friedrich Mie.....»»
Researchers aim to control gene expression by studying the memories of cells
Communication between cells is now believed to activate a memory mechanism that sustains gene expression, a finding based on the work of Dr. Gregory Reeves......»»