New DNA sequencing technique preserves cells" locations within tissues
Within complex tissues such as cancer tumors, individual cells can vary widely from each other. Internally, cancer cells can develop unique DNA mutations and genomic changes, potentially leading to drug resistance, metastasis, or relapse. Externally,.....»»
Scientists identify structural basis of stitched-together protein complexes that recycle most proteins in cells
Scientists at Sanford Burnham Prebys have developed a clearer picture of how crucial machinery in the human cell's recycling process for obsolete and misshapen proteins—known as proteasomes—are formed......»»
Building better bone grafts: Nanofibrous scaffolds to activate two main collagen receptors in bone cells
Each year, about 2.2 million bone-grafting procedures are performed worldwide, the gold standard of care being autografting, which uses the patient's own bone for tooth implantation and to repair and reconstruct parts of the mouth, face and skull......»»
Scientists develop method to control timing of synthetic DNA droplet division
Many cellular functions in the human body are controlled by biological droplets called liquid-liquid phase separation (LLPS) droplets. These droplets, made of soft biological materials, exist inside living cells but are not enclosed by membranes like.....»»
Biologists sequence proteins by pulling them through nanopores
A team of chemical biologists at the University of Washington, working with colleagues at Oxford Nanopore Technologies, has developed a protein sequencing process that involves pulling proteins through nanopores in a lipid membrane. Their paper is pu.....»»
Semimetal-induced covalency achieves high-efficiency electrocatalysis for platinum intermetallic compounds
Compared with other types of batteries, proton exchange membrane fuel cells have the advantages of high discharge power and no pollution, which is also an important carrier for hydrogen energy conversion and utilization. Platinum intermetallic compou.....»»
NASA pilots use specialty suits to validate data
Welcome to NASA's Plankton, Aerosol, Cloud, ocean Ecosystem Postlaunch Airborne eXperiment (PACE-PAX). We've been talking about this validation campaign and now are finally here. "Here" being one of three main locations where PACE-PAX validation effo.....»»
New insights into hot carrier solar cells: Study explores hot electron tunneling and collection to enhance efficiency
Hot carrier solar cells, a concept introduced several decades ago, have long been seen as a potential breakthrough in solar energy technology. These cells could surpass the Shockley–Queisser efficiency limit, which is a theoretical maximum efficien.....»»
Mechanism behind autophagy trigger unveiled
An international research team led by Osaka University has identified a new mechanism crucial for the initiation of autophagy, a self-degradation process cells use to eliminate unneeded or damaged components. In recent years, autophagy has also been.....»»
Yeast chit-chat: How microorganisms communicate food shortages
To grow and survive, tiny organisms such as yeast must sometimes adapt their nutrient sources in response to changes in the environment. FMI researchers have now found that yeast cells communicate with each other to use less favorable nutrients if th.....»»
Compact "gene scissors" enable effective genome editing, may offer future treatment of high cholesterol gene defect
CRISPR-Cas is used broadly in research and medicine to edit, insert, delete or regulate genes in organisms. TnpB is an ancestor of this well-known "gene scissors" but is much smaller and thus easier to transport into cells......»»
Giant panda skin cells transformed into stem cells to help ensure their survival
A team of biologists in China has reprogrammed skin cells from giant pandas into induced pluripotent stem cells (iPSCs), opening the door to creating primordial germ cells that could serve as precursors to sperm and egg cells......»»
New method developed to relocate misplaced proteins in cells
Cells are highly controlled spaces that rely on every protein being in the right place. Many diseases, including cancers and neurodegenerative disorders, are associated with misplaced proteins. In some cancers, for instance, a protein that normally s.....»»
Saturday Citations: Football metaphors in physics; vets treat adorable baby rhino"s broken leg
This week, researchers reported an effective way to protect working dogs from heat stress: training them to dunk their heads in cool water. A new computational technique provided a breakthrough in understanding the so-called "pseudogap" in quantum ph.....»»
New data science tool greatly speeds up molecular analysis of our environment
A research team led by scientists at the University of California, Riverside, has developed a computational workflow for analyzing large data sets in the field of metabolomics, the study of small molecules found within cells, biofluids, tissues, and.....»»
A 41-year-old transformed his body with 2 diet changes and 1 simple workout technique
A 41-year-old transformed his body with 2 diet changes and 1 simple workout technique.....»»
Researchers identify novel endocytic recycling mechanism with "kiss-and-run" membrane fusion
Endocytosis and recycling control the uptake and retrieval of various materials in eukaryotic cells. Mammalian cells have developed several recycling routes, including the relatively extensively studied "fast" and "slow" tubulovesicular recycling pat.....»»
Cooler heads prevail: New research reveals best way to prevent dogs from overheating
As temperatures continue to soar across the country, a simple yet innovative technique could be the key to keeping dogs safe from heat-related illnesses......»»
First-of-its kind tool allows scientists to manipulate cells without touching them
When studying the spread of cancer or the behavior of a virus like the one that causes COVID-19, the irony is that working with these harmful pathogens requires gentleness. Especially in the case of COVID, the particles do not survive well when makin.....»»
Researchers improve tunability in optical differentiation
A new technique may make it easier for researchers to create real-time images of microscopic samples by considering the waves that propagate through sample surfaces as light interacts with them......»»
Redwood Materials signs deal to recycle BMW’s EV batteries in the US
The automaker will use recycled materials from Redwood in its American-made EVs. Enlarge / BMW is moving to cylindrical cells for its sixth-generation EV powertrain, which debuts in the Neue Klasse. And now it has a recycling par.....»»